Telmisartan Treatment Ameliorates Memory Deficits in Streptozotocin-Induced Diabetic Mice via Attenuating Cerebral Amyloidosis

Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain β-amyloid through PPARγ activation

(2013) Li-ping Liu et al.   ACTA PHARMACOLOGICA SINICA

Do angiotensin receptor blockers prevent Alzheimerʼs disease?

(2013) Ihab Hajjar et al.   CURRENT OPINION IN CARDIOLOGY

Do Angiotensin Receptor Blockers Protect Against Alzheimer’s Disease?

(2013) Hitomi Kurinami et al.   DRUGS & AGING

Ameliorative Effects of Telmisartan on the Inflammatory Response and Impaired Spatial Memory in a Rat Model of Alzheimer^|^#8217;s Disease Incorporating Additional Cerebrovascular Disease Factors

(2012) Taro Shindo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats

(2012) Renata Vargas et al.   BRAIN RESEARCH

PPARγ Agonist Pioglitazone Reverses Memory Impairment and Biochemical Changes in a Mouse Model of Type 2 Diabetes Mellitus

(2012) Li-Ying Jiang et al.   CNS Neuroscience & Therapeutics

Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations

(2012) Linda Chami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telmisartan protects against cognitive decline via up-regulation of brain-derived neurotrophic factor/tropomyosin-related kinase B in hippocampus of hypertensive rats

(2012) Takuya Kishi et al.   Journal of Cardiology

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease

(2012) Pablo Garrido-Gil et al.   Journal of Neuroinflammation

Attenuating effect of lisinopril and telmisartan in intracerebroventricular streptozotocin induced experimental dementia of Alzheimer’s disease type: possible involvement of PPAR-γ agonistic property

(2012) Birdavinder Singh et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Leukotriene D4 induces cognitive impairment through enhancement of CysLT1R-mediated amyloid-β generation in mice

(2012) Su-Su Tang et al.   NEUROPHARMACOLOGY

Experimental hypertension induced vascular dementia: Pharmacological, biochemical and behavioral recuperation by angiotensin receptor blocker and acetylcholinesterase inhibitor

(2012) Bhupesh Sharma et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Angiotensin II AT1 Receptor Blockers Ameliorate Inflammatory Stress: A Beneficial Effect for the Treatment of Brain Disorders

(2011) Juan M. Saavedra   CELLULAR AND MOLECULAR NEUROBIOLOGY

Diabetes-Induced Central Cholinergic Neuronal Loss and Cognitive Deficit Are Attenuated by Tacrine and a Chinese Herbal Prescription, Kangen-Karyu: Elucidation in Type 2 Diabetes db/db Mice

(2011) Qi Zhao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia

(2010) Yukiko Kasahara et al.   BRAIN RESEARCH

Increased expression of β amyloid precursor gene in the hippocampus of streptozotocin-induced diabetic mice with memory deficit and anxiety induction

(2010) Sung Wook Jung et al.   JOURNAL OF NEURAL TRANSMISSION

Diabetes Type II: A Risk Factor for Depression–Parkinson–Alzheimer?

(2010) Peter Riederer et al.   NEUROTOXICITY RESEARCH

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice

(2009) Corinne G. Jolivalt et al.   EXPERIMENTAL NEUROLOGY

Cognitive Deficit in Amyloid-β–Injected Mice Was Improved by Pretreatment With a Low Dose of Telmisartan Partly Because of Peroxisome Proliferator-Activated Receptor-γ Activation

(2009) Kana Tsukuda et al.   HYPERTENSION

Angiotensin II Type 1 Receptor Blocker Telmisartan Reduces Cerebral Infarct Volume and Peri-infarct Cytosolic Phospholipase A2 Level in Experimental Stroke

(2009) Tomonori Kobayashi et al.   JOURNAL OF NEUROTRAUMA

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

(2009) Tony Valente et al.   NEUROBIOLOGY OF DISEASE

Downregulation of LPR1 at the blood–brain barrier in streptozotocin-induced diabetic mice

(2009) Hao Hong et al.   NEUROPHARMACOLOGY

Upregulation of RAGE at the blood-brain barrier in streptozotocin-induced diabetic mice

(2009) Li Ping Liu et al.   SYNAPSE

Telmisartan prevented cognitive decline partly due to PPAR-γ activation

(2008) Masaki Mogi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina

(2008) T. Kurihara et al.   DIABETES

Increased amyloid β-peptide (1–40) level in brain of streptozotocin-induced diabetic rats

(2008) Y. Liu et al.   NEUROSCIENCE