Article
Environmental Sciences
Junjie Ao, Xiaona Huo, Jiangtao Zhang, Yuchan Mao, Guohua Li, Jiangfeng Ye, Yuhua Shi, Fan Jin, Shihua Bao, Jun Zhang
Summary: The study indicates that environmental exposure to bisphenol analogues is associated with an increased risk of unexplained recurrent miscarriage (URM), with a dose-response pattern observed for BPAF, BPAP, and BPB. Older women, aged 30 years or above, may be more vulnerable to the effects of these chemicals.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Niedson Correia de Lima Junior, Juliana Franco Camilo, Pamella Rodrigues do Carmo, Marcelle Novaes de Andrade, Bernardo Ferreira Braz, Ricardo Erthal Santelli, Lycia de Brito Gitirana, Andrea Claudia Freitas Ferreira, Denise Pires de Carvalho, Leandro Miranda-Alves, Glaecir Roseni Mundstock Dias
Summary: Subacute exposure to lead acetate disrupts thyroid gland function in both sexes, leading to changes in learning and memory abilities.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Junjie Ao, Yongjie Liu, Weifeng Tang, Jun Zhang
Summary: This study investigates the potential effects and mechanisms of bisphenol S (BPS) exposure on human colon mucosal epithelial cells. The results show that BPS exposure increases the production of pro-inflammatory cytokines, destroys the tight junctions of the cells, and affects neurotransmitters. These findings suggest that BPS exposure may disrupt the balance of the gut-brain axis, leading to inflammatory cytokine production and tight junction destruction.
Editorial Material
Biochemistry & Molecular Biology
Borja Quiroga
Summary: BPA, a common component of plastics worldwide, has been shown to act as an endocrine disruptor with some hormonal functions. High levels of BPA are related to cardiovascular events and carcinogenesis pathways, and CKD patients have higher serum concentrations of BPA due to impaired renal function. Efforts to reduce BPA levels in these patients include developing BPA-free dialysis filters and other techniques.
Article
Psychology, Biological
Miao Gong, Han Song, Yan Dong, Ziqing Huai, Yaling Fu, Panpan Yu, Boya Huang, Rui Yang, Yi Guo, Qian Meng, Yuan Gao, Li Song, Qingjun Guo, Qiang Gao, Xi Yin, Sheng Wang, Yun Shi, Haishui Shi
Summary: This study found that exposure to BPAF significantly affects emotional behaviors in adult and offspring mice in a sex-dependent manner. Adult male mice exposed to BPAF showed reduced anxiety and depression-like behaviors, while female mice showed increased anxiety and depression-like behaviors, as well as enhanced novel object recognition memory formation and impaired contextual fear conditioning memory formation. Maternal exposure to BPAF resulted in anxiety-like effects and anti-depression-like effects in male offspring mice during adulthood, while increasing anxiety and depression-like behaviors in female offspring mice during adulthood.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Biochemistry & Molecular Biology
Zhiying Liang, Yafen Guo, Duan Pi, Xiang Li, Bingying Li, Yongsi Huang, Xiaohong Song, Ramji Kumar Bhandari, Xuegeng Wang
Summary: Recent studies have shown that the concentration of bisphenol F (BPF) in water has dramatically increased, raising concerns about its adverse effects on aquatic organisms and humans. This study conducted acute toxic exposure and developmental exposure experiments using Chinese medaka, and found that BPF at a concentration of 2000 ng/L significantly affected the development of Chinese medaka and caused endocrine-related abnormalities in the transcriptional network of genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Rie Yanagisawa, Eiko Koike, Tin-Tin Win-Shwe, Hirohisa Takano
Summary: This study found that oral exposure to low-dose BPS may exacerbate allergic asthmatic responses by enhancing Th2-polarized responses and activating the MLN cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Environmental Sciences
Tijana Vasiljevic, Tom Harner
Summary: BPA and its analogues are widely used in plastic synthesis, potentially disrupting the hormonal structure of living organisms. Reports on BPA levels in air are limited, mainly due to anthropogenic activities. China reported the highest outdoor air levels of BPA near a low-tech e-waste recycling site, and indoor dust also revealed bisphenol analogues used in BPA-free products.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Endocrinology & Metabolism
Giada Frenzilli, Joan Martorell-Ribera, Margherita Bernardeschi, Vittoria Scarcelli, Elisabeth Jonsson, Nadia Diano, Martina Moggio, Patrizia Guidi, Joachim Sturve, Noomi Asker
Summary: The study shows that both bisphenol A and its alternative bisphenol S can cause endocrine disrupting and genotoxic effects in brown trout, indicating two different mechanisms of damage underlying the activities of bisphenol A and bisphenol S. Bisphenol A primarily increases micronuclei frequency in fish erythrocytes, while bisphenol S may cause damage through other mechanisms.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Nutrition & Dietetics
Muhammad Faisal Manzoor, Tayyaba Tariq, Birjees Fatima, Amna Sahar, Farwa Tariq, Seemal Munir, Sipper Khan, Muhammad Modassar Ali Nawaz Ranjha, Aysha Sameen, Xin-An Zeng, Salam A. Ibrahim
Summary: This review provides detailed information on the presence and concentrations of BPA in the environment and food sources, as well as its toxic and disruptive effects on health. Studies have confirmed the endocrine-disrupting, carcinogenic, and mutagenic effects of BPA. The review also discusses measures to address this toxic chemical.
FRONTIERS IN NUTRITION
(2022)
Article
Environmental Sciences
Julie Bang Hansen, Niels Bilenberg, Clara Amalie Gade Timmermann, Richard Christian Jensen, Hanne Frederiksen, Anna-Maria Andersson, Henriette Boye Kyhl, Tina Kold Jensen
Summary: This study aimed to assess the association between in utero exposure to BPA and symptoms of ADHD and ASD in 2 and 5-year old Danish children. The results showed that there were no associations between maternal BPA exposure and ASD at age 2 years or ADHD at age 5 years, but a potential link between BPA exposure and ASD symptoms in 5-year old children, especially girls, was found.
ENVIRONMENTAL HEALTH
(2021)
Article
Chemistry, Multidisciplinary
Eujung Kim, Minjung Song, Adam Gopal Ramu, Dongjin Choi
Summary: Bisphenol A (BPA), a common chemical used in plastic production, has emerged as a serious environmental concern due to its potential toxicity to plants. This study aimed to investigate the mechanism of BPA-induced root cells by examining the effects of BPA on the ultrastructure and function of soybean plant root tip cells. Changes in plant root cell tissues after BPA exposure were observed, and the accumulation of BPA in different plant parts was analyzed. The findings provide insight into how BPA can alter plant root growth.
Article
Pharmacology & Pharmacy
Huimin Wang, Xuepei Lei, Zhuo Zhang, Mohammad Mehdi Ommati, Zhongwei Tang, Jianqin Yuan
Summary: The study indicates that BPA exposure has detrimental effects on cognitive function and insulin signaling pathway in male offspring mice, potentially posing a risk for long-term neurodegeneration.
Article
Environmental Sciences
Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande, Susana Santos
Summary: Higher maternal bisphenol S urine concentrations, especially in the first trimester, seem to be associated with larger fetal head circumference, higher weight, and a lower risk of being small size for gestational age at birth. Other bisphenols were not consistently associated with fetal growth outcomes.
ENVIRONMENTAL HEALTH
(2021)
Review
Environmental Sciences
Mao-Hsun Lin, Chun-Ying Lee, Yun-Shiuan Chuang, Chia-Lung Shih
Summary: This study conducted an umbrella review of published meta-analyses to investigate the associations between Bisphenol A (BPA) exposure and human health outcomes. A total of 14 reports were included, and the results showed that BPA exposure was associated with various health outcomes including preterm birth, allergic diseases, kidney disease, polycystic ovarian syndrome, obesity, type 2 diabetes, cardiovascular disease, hypertension, and inflammation and immune responses. These findings highlight the serious impact of BPA exposure on human health and call for meaningful regulations by the World Health Organization to reduce environmental contamination.
ENVIRONMENTAL RESEARCH
(2023)