Article
Chemistry, Medicinal
Olimpia Ortiz-Arrabal, Ainhoa Irastorza-Lorenzo, Fernando Campos, Miguel Angel Martin-Piedra, Victor Carriel, Ingrid Garzon, Paula Avila-Fernandez, Maria Jose de Frutos, Emilio Esteban, Javier Fernandez, Agustin Janer, Antonio Campos, Jesus Chato-Astrain, Miguel Alaminos
Summary: Marine-origin polysaccharides, especially agarose, have been extensively studied as scaffolds for tissue engineering. We have developed new fibrin-agarose (FA) biomaterials using different types and concentrations of agaroses, which showed high biocompatibility and varied biomechanical properties. In vivo experiments demonstrated the biocompatibility of FA tissues and histological analysis indicated a pro-regenerative process with M2-type CD206-positive macrophages. These findings confirm the clinical potential of FA biomaterials for tissue engineering applications, allowing for the selection of specific agarose types and concentrations to meet desired biomechanical properties and in vivo reabsorption times.
Article
Biochemistry & Molecular Biology
Ainhoa Irastorza-Lorenzo, David Sanchez-Porras, Olimpia Ortiz-Arrabal, Maria Jose de Frutos, Emilio Esteban, Javier Fernandez, Agustin Janer, Antonio Campos, Fernando Campos, Miguel Alaminos
Summary: Five agarose types were evaluated in tissue engineering, with biomechanical properties and biocompatibility strongly associated with agarose concentration, suggesting potential for generating specific agarose-based hydrogels for clinical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Medicine, Research & Experimental
Mohammad Dahri, Nima Beheshtizadeh, Nasrin Seyedpour, Amin Nakhostin-Ansari, Faezeh Aghajani, Simin Seyedpour, Moein Masjedi, Fatemeh Farjadian, Reza Maleki, Khosro Adibkia
Summary: Immunotherapy is an important treatment for various diseases, and different approaches using biomaterials and devices have been studied. Transdermal immunotherapy using microneedles is commonly used for cancer, infectious diseases, and allergic and autoimmune disorders. The biomaterials used in transdermal immunotherapy have different shapes, sizes, and sensitivities to external stimuli.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Mariana Branquinho, Sheila O. Ferreira, Rui D. Alvites, Adriana F. Magueta, Maxim Ivanov, Ana Catarina Sousa, Irina Amorim, Fatima Faria, M. H. Fernandes, Paula M. Vilarinho, Ana Colette Mauricio
Summary: This study evaluated medical devices made of 316L stainless steel with a PLLA coating for mechanical and functional support for bone injuries. Results showed superior outcomes both in vitro and in vivo, suggesting that the PLLA coating may have osteo-inductive properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Lunyong Zhang, Yongjiang Huang, Xiang Cheng, Hongbo Fan, Yu Sun, Zhiliang Ning, Fuyang Cao, Jianfei Sun
Summary: This study investigated the biocompatibility of Zr-based bulk metallic glasses, showing that BMG material treated by micro-arc oxidation technology exhibits good biocompatibility comparable to Ti-6Al-4V alloy. By adjusting the treatment voltage, a surface with high density uniform pores and suitable roughness can be obtained, leading to improved platelet adhesion, blood compatibility, mucous membrane irritation, inflammation, and cell recovery during subcutaneous implantation tests. These findings may promote the future applications of Zr-based BMGs as biomaterials.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Review
Chemistry, Medicinal
Jingyuan Li, Hong Xiang, Qian Zhang, Xiaoqing Miao
Summary: Materials derived from natural plants and animals have great potential for transdermal drug delivery. Polysaccharides, which are widely derived from marine, herbal, and microbial sources, have advantages over synthetic polymers, such as non-toxicity, biodegradability, ease of modification, biocompatibility, targeting, and antibacterial properties. Polysaccharide-based transdermal drug delivery vehicles, such as hydrogel, film, microneedle, and tissue scaffolds, are being developed to improve drug delivery efficiency.
Article
Materials Science, Multidisciplinary
Yuji Kisaka, Satoshi Miki, Nobuo Sekiguchi, Fumiaki Kimura, Shinichi Tashiro, Manabu Tanaka, Shumpei Ozawa, Tomone Suwa, Yoshikazu Takahashi
Summary: The TIG welding of high manganese stainless steels was conducted with sulfur contents of 5 and 20 ppm, revealing an increase in penetration depth due to an inward fluid flow caused by the temperature increase. Precise measurements of surface tension using the electromagnetic levitation technique explained that Marangoni convection was the dominant factor in inducing fluid flow in samples with 20 ppm sulfur content. Numerical calculations considering various driving forces confirmed that Marangoni convection controlled the fluid flow direction in the molten pool.
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE
(2021)
Article
Instruments & Instrumentation
Alexander A. Ryabin, Dmitry Pelegov
Summary: This study investigates the application of micro-Raman spectroscopy in powder samples with irregular shapes and sizes close to the wavelength of the probing laser. The results show that the vertical resolution should be described qualitatively rather than quantitatively for such samples. Additionally, Raman probing can be used for both multilayer and superficial analysis.
APPLIED SPECTROSCOPY
(2022)
Article
Physics, Multidisciplinary
Liu Jun, Wang Pei, Sun Zhi-Yuan, Zhang Feng-Guo, He An-Min
Summary: This paper theoretically analyzes the phenomenon of gas penetrating the metal micro spallation zone, and provides calculation formulas for the maximum penetration depth, sealing time, and maximum mass of the gas. The analysis is conducted under quasi-static and semi-dynamic conditions to determine the upper and lower limits of gas penetration. The study emphasizes the need for further in-depth research based on experimental and simulation confirmation.
ACTA PHYSICA SINICA
(2021)
Article
Engineering, Biomedical
P. Hauschwitz, M. Klicova, S. Mullerova, R. Bicistova, M. Prochazka, J. Brajer, M. Chyla, M. Smrz, J. Chvojka, T. Mocek
Summary: Biocompatibility is a crucial issue for implants, particularly in the case of stainless steel with medium to low biocompatibility, as it can result in osseointegration failure or implant rejection. This study analyzed two types of surfaces, namely laser induced periodic surface structure (LIPSS) with nanogrooves and square-shaped micropillars, to control cell growth and improve biocompatibility. A high energy ultrashort pulsed laser system with multi-beam and beamshaping technology was applied to rapidly and efficiently produce these surfaces, with a significant increase in productivity compared to single beam methods. In vitro analysis demonstrated that micro and nanostructured surfaces facilitate cell attachment and proliferation, with up to a 496% increase in cell number. Additionally, the combination of LIPSS and micropillars enabled precise cell orientation along the periodic microgroove pattern. These findings highlight the potential for mass production of functionalized implants with controlled cell organization and growth, reducing the risk of implant failure due to low biocompatibility.
BIOMEDICAL MATERIALS
(2023)
Article
Construction & Building Technology
Rui Zhong, Fengling Zhang
Summary: This experimental study evaluated the effectiveness of passive and active strategies in improving the projectile impact resistance of cementitious matrices. The results showed that modifying the bond structure and aggravating projectile damage can significantly reduce penetration depth and crack formation.
CEMENT & CONCRETE COMPOSITES
(2023)
Review
Engineering, Manufacturing
Amit Mahajan, Sandeep Devgan, Dinesh Kalyanasundaram
Summary: Surface alterations of metallic biomaterials are crucial for enhancing the performance and longevity of bioimplants. Advancements in biomaterials, tissue engineering, and surface modification have significantly improved cell proliferation and regeneration on implants. Different surface modification approaches have been employed to enhance the biocompatibility, corrosion resistance, and wear performance of metallic biomaterials.
MATERIALS AND MANUFACTURING PROCESSES
(2023)
Article
Chemistry, Physical
Mohamad Alhajhamoud, Levent Candan, Mehmet Alp Ilgaz, Ibrahim Cinar, Sayit Ozbey, Selma Corovic, Damijan Miljavec, Ersin Kayahan
Summary: This study investigated and proposed optimal welding parameters for neodymium-doped yttrium aluminum garnet (Nd:YAG)-pulsed laser welding of austenitic stainless steel 316L. The results showed that the largest depth of penetration was achieved with a certain laser energy in air medium and a higher laser energy in serum medium. The findings suggest promising possibilities for laser welding in in-vivo settings.
Article
Dermatology
Markus Lubda, Maximilian Zander, Andrew Salazar, Harald Kolmar, Joerg von Hagen
Summary: This study compared the penetration of active ingredients at different depths in the skin using microdialysis, finding that physicochemical properties influenced penetration. The results showed that the lipophilic nature of active ingredients affected their penetration into the dermis, which in turn impacted the concentration reaching the target site.
SKIN PHARMACOLOGY AND PHYSIOLOGY
(2021)
Article
Instruments & Instrumentation
Abdul Mohizin, Jung Kyung Kim
Summary: This study aims to address the lack of fundamental knowledge on the impact of interfaces on the injection profiles of needle-free jet injection (NFJI) devices.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2022)
Article
Chemistry, Analytical
Xiuru Xu, Min Yin, Na Li, Wei Wang, Bolun Sun, Ming Liu, Dongwei Zhang, Zhenyu Li, Ce Wang
Article
Materials Science, Multidisciplinary
Aiyuan Li, Lijia Yan, Chao He, Yanan Zhu, Dongwei Zhang, Imran Murtaza, Hong Meng, Osamu Goto
JOURNAL OF MATERIALS CHEMISTRY C
(2017)
Article
Materials Science, Multidisciplinary
Wenjun Xu, Yaowu He, Imran Murtaza, Dongwei Zhang, Aiyuan Li, Zhao Hu, Xingwei Zeng, Yitong Guo, Yanan Zhu, Ming Liu, Hong Meng
JOURNAL OF MATERIALS CHEMISTRY C
(2017)
Article
Materials Science, Multidisciplinary
Aiyuan Li, Lijia Yan, Ming Liu, Imran Murtaza, Chao He, Dongwei Zhang, Yaowu He, Hong Meng
JOURNAL OF MATERIALS CHEMISTRY C
(2017)
Article
Nanoscience & Nanotechnology
Chao He, Aiyuan Li, Lijia Yan, Dongwei Zhang, Yanan Zhu, Haibiao Chen, Hong Meng, Osamu Goto
ADVANCED ELECTRONIC MATERIALS
(2017)
Article
Materials Science, Multidisciplinary
Mo Chen, Yanan Zhu, Chao Yao, Dongwei Zhang, Xingwei Zeng, Imran Murtaza, Haibiao Chen, Seiya Kasai, Hong Meng, Osamu Goto
ORGANIC ELECTRONICS
(2018)
Article
Materials Science, Multidisciplinary
Weiqi Zhang, Han Wang, Jingsheng Miao, Yanan Zhu, Muhammad Umair Ali, Ting Xu, Liang Zhao, Dongwei Zhang, Gufeng He, Hong Meng
ORGANIC ELECTRONICS
(2018)
Article
Nanoscience & Nanotechnology
Dongwei Zhang, So Yokomori, Ryohei Kameyama, Changbin Zhao, Akira Ueda, Lei Zhang, Reiji Kumai, Youichi Murakami, Hong Meng, Hatsumi Mori
Summary: The derivatives of anthracene show strong emission and charge carrier mobility within a molecule, with the alkyl chain length playing a crucial role in crystal structures, thermal properties, and photophysical characteristics. Adjusting the alkyl chain length can significantly impact the charge mobilities, with shorter chains generally leading to higher mobilities due to enhanced film order and intermolecular charge transport properties.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Dongwei Zhang, Changbin Zhao, Xiwei Zheng, Lijie Wu, Jinhao Xu, Liguo Zhou, Ping Kwan Johnny Wong, Wen Zhang, Yaowu He
Summary: Benzothieno[3,2-b][1]benzothiophene (BTBT) derivatives are excellent organic semiconductors for hole transport, although they have poor luminescence properties. In this study, three organic semiconductors based on phenyl-BTBT molecule core were synthesized, showing blue fluorescence with relatively high photoluminescence quantum yields (PLQYs). Among them, the DBEP-BTBT film exhibited an absolute PLQY as high as 12%, which is a rare and precious characteristic among BTBT derivatives.
Article
Chemistry, Physical
Dongwei Zhang, Liguo Zhou
Summary: This study systematically investigated the mobility anisotropies of three types of BTBT derivatives and found that long alkyl chains and phenyl substitutions can promote low anisotropy in BTBTs. Additionally, the effects of substitution position on mobility anisotropy were discussed, and 2,7- and 3,8-substitutions were found to be more suitable for developing low anisotropy BTBT molecules.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Materials Science, Multidisciplinary
Dongwei Zhang, Liguo Zhou, Ping Kwan Johnny Wong, Wen Zhang
Summary: The two crucial factors influencing the mobility anisotropy in organic semiconductors (OSCs) are the molecular packing architecture parameter theta(T) and ratio R. The length of the alkyl chain plays a role in balancing intermolecular charge-transfer properties, and the bulkiness of the side chains affects the angle theta(T). Additionally, the bulkiness of the side chains can adjust the intermolecular distance and promote the balance of the intermolecular charge-transfer property.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Multidisciplinary
Xiaolong Chen, Dongwei Zhang, Yaowu He, Muhammad Umair Ali, Yuting Wu, Changbin Zhao, Peiheng Wu, Chaoyi Yan, Fred Wudl, Hong Meng
MATERIALS CHEMISTRY FRONTIERS
(2020)
Article
Materials Science, Multidisciplinary
Jianing Wang, Huinan Yu, Tianchen Fu, Changbin Zhao, Hongtao Yu, Zhijun Liu, Qiang He, Dongwei Zhang, Hong Meng, Wei Huang
JOURNAL OF MATERIALS CHEMISTRY C
(2020)
Article
Materials Science, Multidisciplinary
Xingwei Zeng, Dongwei Zhang, Yanan Zhu, Mo Chen, Haibiao Chen, Seiya Kasai, Hong Meng, Osamu Goto
JOURNAL OF MATERIALS CHEMISTRY C
(2019)
Article
Nanoscience & Nanotechnology
Yantong Chen, Chao Li, Xiuru Xu, Ming Liu, Yaowu He, Imran Murtaza, Dongwei Zhang, Chao Yao, Yongfeng Wang, Hong Meng
ACS APPLIED MATERIALS & INTERFACES
(2017)