☆ 4.6 Article

Preparation of magnetic molecularly imprinted polymers for bisphenol A and its analogues and their application to the assay of bisphenol A in river water

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2013)

期刊

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

卷 75, 期 -, 页码 180-185

出版社

ELSEVIER SCIENCE BV

DOI: 10.1016/j.jpba.2012.11.030

关键词

Magnetic molecularly imprinted polymer; Sample preparation; Environmental analysis; Bisphenols

类别

Chemistry, Analytical Pharmacology & Pharmacy

资金

Ministry of Environment
Ministry of Education, Culture, Sports, Science and Technology, Japan [19390013]
Grants-in-Aid for Scientific Research [19390013, 25460051, 25460050] Funding Source: KAKEN

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Protocol

Reagent

摘要

Magnetic molecularly imprinted polymers (M-MIPs) for bisphenol A (BPA) and its structural analogues have been prepared by a multi-step swelling and polymerization method using uniformly-sized magnetic particles as a shape template. Binding experiments and Scatchard analyses revealed that two classes of binding sites were formed on M-MIPBPA. The retention and molecular-recognition properties of M-MIPs for BPA and its structural analogues were evaluated using a mixture of phosphate buffer and acetonitrile or a mixture of water and acetonitrile as a mobile phase by LC. M-MIPs for BPA and [H-2(16)]BPA (BPA-d(16)), M-MIPBPA and M-MIPBPA-d16, showed almost the same imprinting factors for BPA, while M-MIP for bisphenol B (2,2-bis(4-hydroxyphenyl)butane, BPB), M-MIPBPB, gave the moderate imprinting factor for BPA. Furthermore, M-MIPBPB was applied for the selective extraction and determination of BPA in environmental water samples. The concentration of BPA in river water samples was determined to be 68 ng/L. (C) 2012 Elsevier B.V. All rights reserved.

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Analysis of the permeable and retainable components of Cayratia japonica ointment through intact or broken skin after topical application by UPLC-Q-TOF-MS/MS combined with in vitro transdermal assay

Xuelong Zhao, Ruixue Dai, Jing Wang, Liangliang Cao, Peidong Chen, Weifeng Yao, Fangfang Cheng, Beihua Bao, Li Zhang

Summary: This study identified the skin-permeable and skin-retainable components of Cayratia japonica ointment and found that flavonoids are the main active components that play a crucial role in the inflammatory and proliferative phases of wound healing.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2024)

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