Article
Nutrition & Dietetics
Sarah E. Twardowski, Jean Wactawski-Wende, Kathleen M. Hovey, Christopher A. Andrews, Hailey R. Banack, Michael J. LaMonte, Amy E. Millen
Summary: The study found a negative association between plasma 25-hydroxyvitamin D (25[OH]D) concentrations and salivary CRP concentrations in postmenopausal women, which attenuated after adjusting for other factors. However, there was no significant association between 25[OH]D and serum CRP concentrations.
Article
Dentistry, Oral Surgery & Medicine
Xiaoyun Liu, Bichong Dai, Yuanyuan Chuai, Menglin Hu, Hengguo Zhang
Summary: This study investigates the potential relationship between different levels of vitamin D and severe periodontal attachment loss in American adults. The findings suggest that low levels of vitamin D are associated with the progression of attachment loss, while higher levels of vitamin D may be beneficial for periodontal health.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Medicine, General & Internal
Martina Ferrillo, Mario Migliario, Andrea Roccuzzo, Pedro Molinero-Mourelle, Giovanni Falcicchio, Giuseppina Rosaria Umano, Federica Pezzotti, Pier Luigi Foglio Bonda, Dario Calafiore, Alessandro de Sire
Summary: The study found a correlation between periodontal disease, low vitamin D levels, preterm birth, and low birth weight in pregnant women. Poor oral health and vitamin D deficiency in pregnant women were significantly associated with higher rates of preterm birth and low birth weight.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Masanori Iwasaki, Keiko Motokawa, Maki Shirobe, Misato Hayakawa, Yuki Ohara, Yoshiko Motohashi, Ayako Edahiro, Hisashi Kawai, Yoshinori Fujiwara, Yasuyuki Sakata, Kazushige Ihara, Yutaka Watanabe, Shuichi Obuchi, Hirohiko Hirano
Summary: This study aimed to evaluate the association between vitamin D status and periodontal inflammation in communitydwelling older adults. The results showed a non-linear relationship between serum 25-hydroxyvitamin D (25(OH)D) levels and periodontal inflammation, with low vitamin D levels being associated with a higher risk of periodontal inflammation. This has important implications for the prevention and treatment of periodontal inflammation in older adults.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Review
Nutrition & Dietetics
Gianina Tapalaga, Bogdan Andrei Bumbu, Sandhya Rani Reddy, Sai Diksha Vutukuru, Akhila Nalla, Felix Bratosin, Roxana Manuela Fericean, Catalin Dumitru, Doru Ciprian Crisan, Nicoleta Nicolae, Magda Mihaela Luca
Summary: Prenatal Vitamin D levels may have an impact on dental health outcomes in children. The association between Vitamin D levels and enamel defects and tooth erosion varied across different studies. Vitamin D insufficiency was identified as a significant risk factor for enamel defects, while high prenatal Vitamin D levels indicated a protective effect against Hypomineralized Second Primary Molars and Molar Incisor Hypomineralization. However, there were variations in the assessment and prevalence of Vitamin D deficiency or insufficiency, and more research is needed to determine the optimal Vitamin D intake during pregnancy.
Review
Nutrition & Dietetics
Jose Luis Mansur, Beatriz Oliveri, Evangelina Giacoia, David Fusaro, Pablo Rene Costanzo
Summary: Vitamin D deficiency in pregnancy and infants may lead to health issues such as rickets, preeclampsia, and fetal growth restriction; supplementation with Vitamin D can reduce the risk of complications for pregnant women, fetuses, and newborns.
Article
Nutrition & Dietetics
Jinhua Wu, Bule Shao, Xing Xin, Wenliang Luo, Minjia Mo, Wen Jiang, Shuting Si, Shuojia Wang, Yu Shen, Yunxian Yu
Summary: This study explored the associations of vitamin D metabolic pathway gene polymorphisms with gestational 25(OH)D levels in pregnant women, and found that the associations varied by season and VD supplements. Additionally, the Gc isoform had a significant impact on gestational 25(OH)D levels.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Lisa Daneels, Dries S. Martens, Soumia Arredouani, Jaak Billen, Gudrun Koppen, Roland Devlieger, Tim S. Nawrot, Manosij Ghosh, Lode Godderis, Sara Pauwels
Summary: The study found a positive association between maternal vitamin D intake (diet + supplements) and newborn TL, particularly during the first trimester. However, there was no significant association between mean maternal serum 25-OHD concentrations during pregnancy and newborn TL.
Review
Nutrition & Dietetics
Andreea Bianca Stoica, Claudiu Marginean
Summary: This article reviews the impact of vitamin D deficiency on the health of infants, emphasizing its global significance and the need for further research and strategies. While conflicting results exist regarding the effects of vitamin D, it is clear that deficiency has significant implications, particularly for infants.
Article
Nutrition & Dietetics
Spyridon N. Karras, Erdinc Dursun, Merve Alaylioglu, Duygu Gezen-Ak, Stefan Pilz, Cedric Annweiler, Fatme Al Anouti
Summary: This study aimed to evaluate the combined effect of maternal and neonatal VDBP polymorphism heterogeneity in conjunction with different maternal and neonatal 25(OH)D cutoffs on neonatal anthropometric profile at birth. The findings suggest a potential role for neonatal VDBP genotypes rs2298850 and rs4588, in conjunction with specific neonatal 25(OH)D cutoffs, in affecting neonatal growth and development. However, no significant effects were observed for maternal VDBP polymorphisms or maternal 25(OH)D concentrations at birth on neonatal anthropometry.
Article
Public, Environmental & Occupational Health
Su H. Chu, Mengna Huang, Rachel S. Kelly, Priyadarshini Kachroo, Augusto A. Litonjua, Scott T. Weiss, Jessica Lasky-Su
Summary: This study found that higher levels of maternal vitamin D in the third trimester are associated with a lower risk of ADHD in offspring, with a stronger effect observed in male offspring.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Claire Stenhouse, Emma Hurst, Richard J. Mellanby, Cheryl J. Ashworth
Summary: Recent evidence suggests that vitamin D plays a crucial role in pregnancy, fetal growth, and development in various mammalian species. However, little is known about the changes in maternal vitamin D levels during pregnancy in pigs and its relationship with litter characteristics. This study examined the levels of 25(OH)D in maternal plasma at different gestational days and found a significant increase between days 18 and 30. The study also investigated the association between maternal vitamin D levels and various litter characteristics, such as gilt weight, ovulation rate, mean litter weight, number of live fetuses, prenatal survival rate, and sex ratio of the litter. The results showed that maternal 25(OH)D levels were positively associated with prenatal survival rate on day 60 and inversely associated with gilt weight on day 90. Maternal plasma 25(OH)D levels were also inversely associated with the percentage of male fetuses in the litter on day 90. This study provides valuable insights into the temporal changes in maternal vitamin D levels during pregnancy and its impact on economically important litter characteristics. Understanding the role of vitamin D in fetal growth during key developmental stages is vital for improving reproductive success in livestock species.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Lukasz Ustianowski, Klaudia Ustianowska, Klaudia Gurazda, Marcin Rusinski, Piotr Ostrowski, Andrzej Pawlik
Summary: Periodontitis is a common disorder affecting the bone and soft tissues of the periodontal complex. Recent studies have highlighted the alleged role of vitamins, such as vitamin C (VitC) and vitamin D (VitD), in the development and treatment of the disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Spyridon N. Karras, Erdinc Dursun, Merve Alaylioglu, Duygu Gezen-Ak, Fatme Al Anouti, Stefan Pilz, Pawel Pludowski, Edward Jude, Kalliopi Kotsa
Summary: Dysregulation of vitamin D-binding protein has been associated with various pregnancy complications. The effects of VDBP polymorphisms on adipokine profiles in mothers and neonates have not been fully investigated. This study found that VDBP polymorphisms had minimal impact on adiponectin, irisin, and VDBP concentrations at birth under different vitamin D status cut-offs.
Review
Nutrition & Dietetics
Heng Zhang, Shumin Wang, Lingjin Tuo, Qixiao Zhai, Jingjing Cui, Daozhen Chen, Dexiang Xu
Summary: Vitamin D plays an important role in pregnancy, with low levels being associated with adverse pregnancy outcomes. This review summarizes the potential mechanisms of how vitamin D regulates these outcomes and aims to provide a basis for public health intervention strategies.
Article
Pediatrics
Giulia M. Martone, Heather K. Lehman, Todd C. Rideout, Divya Choudhary, Claire E. Cameron, Emily Oken, Sheryl L. Rifas-Shiman, Carlos A. Camargo, Diane R. Gold, Xiaozhong Wen
Summary: The study found that children who had delayed introduction of eggs after 12 months had a significantly higher risk of egg allergy at 2 years and the risk persisted into early adolescence at 12 years. This suggests that introducing eggs before 12 months could help prevent egg allergy.
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2023)
Article
Critical Care Medicine
Brandon-R. Bedell, Krislyn-M. Boggs, Janice-A. Espinola, Ashley-F. Sullivan, Kohei Hasegawa, Margaret Samuels-Kalow, Kori -S. Zachrison, Carlos-A. Camargo Jr
Summary: There are discrepancies between trauma center certifications in the U.S., with many states maintaining unique certification systems. This study investigates the similarity between the national trauma certification program established by the American College of Surgeons (ACS) and state certifications, and creates a unified national trauma center database.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Nutrition & Dietetics
Raphaelle Varraso, Orianne Dumas, Fred K. Tabung, Krislyn M. Boggs, Teresa T. Fung, Frank Hu, Edward Giovannucci, Frank E. Speizer, Walter C. Willett, Carlos A. Camargo
Summary: This study aimed to determine if adherence to a healthful plant-based diet is associated with a lower risk of COPD, while adherence to an unhealthful plant-based diet is associated with a higher risk of COPD. Findings showed that participants with the highest hPDI score had a 46% lower risk of COPD, while those with the highest uPDI score had a 39% higher risk of COPD.
Article
Allergy
Rachel L. Miller, Holly Schuh, Aruna Chandran, Izzuddin M. Aris, Casper Bendixsen, Jeffrey Blossom, Carrie Breton, Carlos A. Camargo Jr, Glorisa Canino, Kecia N. Carroll, Sarah Commodore, Jose F. Cordero, Dana M. Dabelea, Assiamira Ferrara, Rebecca C. Fry, Jody M. Ganiban, James E. Gern, Frank D. Gilliland, Diane R. Gold, Rima Habre, Marion E. Hare, Robyn N. Harte, Tina Hartert, Kohei Hasegawa, Gurjit K. Khurana Hershey, Daniel J. Jackson, Christine Joseph, Jean M. Kerver, Haejin Kim, Augusto A. Litonjua, Carmen J. Marsit, Cindy McEvoy, Eneida A. Mendonca, Paul E. Moore, Flory L. Nkoy, Thomas G. O'Connor, Emily Oken, Dennis Ownby, Matthew Perzanowski, Katherine Rivera-Spoljaric, Patrick H. Ryan, Anne Marie Singh, Joseph B. Stanford, Rosalind J. Wright, Robert O. Wright, Antonella Zanobetti, Edward Zoratti, Christine C. Johnson
Summary: This study found that the incidence rates of asthma with recurrent exacerbations (ARE) are influenced by time, geography, age, race and ethnicity, sex, and parental history. Children aged 2-4 years, Hispanic Black and non-Hispanic Black children, and those with a parental history of asthma had the highest rates of ARE.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Immunology
Michihito Kyo, Zhaozhong Zhu, Ryohei Shibata, Michimasa Fujiogi, Jonathan M. Mansbach, Carlos A. Camargo, Kohei Hasegawa
Summary: This study identified specific nasopharyngeal lipids that can differentiate between respiratory syncytial virus (RSV) and rhinovirus (RV) bronchiolitis in infants. These lipids, including phosphatidylcholine (18:2/18:2), dihydroceramide (16:0), and eicosapentaenoic acid, are also associated with the severity of bronchiolitis.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Obstetrics & Gynecology
Steven J. Ondersma, Amii M. Kress, Annemarie Stroustrup, Robert D. Annett, Lyndsay A. Avalos, Maria Talavera-Barber, Patricia A. Brennan, Carlos A. Camargo, Elisabeth Conradt, Anne L. Dunlop, Amy J. Elliott, Monique M. Hedderson, Ximin Li, Monica McGrath, Ruby H. N. Nguyen, Grier P. Page, Sheela Sathyanarayana, Barry Lester
JOURNAL OF PERINATOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Heidi Makrinioti, Zhaozhong Zhu, Carlos A. Camargo, Valentina Fainardi, Kohei Hasegawa, Andrew Bush, Sejal Saglani
Summary: Obesity-related asthma in childhood is a heterogeneous phenotype, with prevalence increasing. Observational studies have found that early-life obesity or weight gain are risk factors for childhood asthma development, and the reverse association is also described. Obese children with asthma have poorer symptom control and more asthma attacks compared to non-obese children with asthma. Clinical trials have found that some obese children with asthma do not respond well to usual treatment.
Letter
Medicine, General & Internal
Christopher L. Bennett, Krislyn M. Boggs, Cameron J. Gettel, Wendy W. Sun, Arjun K. Venkatesh, Carlos A. Camargo
Article
Emergency Medicine
Son H. McLaren, Ying Shelly Qi, Janice A. Espinola, Jonathan M. Mansbach, Peter S. Dayan, Carlos A. Camargo
Summary: This article aims to identify characteristics associated with mild bronchiolitis in infants <= 90 days old. The results show that older age (61-90 days), adequate oral intake, and oxygen saturation >= 94% are factors associated with mild bronchiolitis.
JOURNAL OF THE AMERICAN COLLEGE OF EMERGENCY PHYSICIANS OPEN
(2023)
Article
Emergency Medicine
Scott A. Goldberg, Emma Chadwick, Supriya Makam, Hridaya J. Shah, Michelle B. Bass, Mohammad A. Hasdianda, Gregory Peters, Carlos A. Camargo Jr, Rebecca E. Cash
Summary: Since the publication of the National EMS Research Agenda in 2001, there has been an increase in EMS-specific research and NIH-funded grants. EMS-related publications have tripled and the number of funded EMS research grants has nearly quintupled in the United States over the past 20 years.
ANNALS OF EMERGENCY MEDICINE
(2023)
Article
Medical Informatics
Jeffrey A. Kline, Brian Reed, Alex Frost, Naomi Alanis, Meylakh Barshay, Andrew Melzer, James W. Galbraith, Alicia Budd, Amber Winn, Eugene Pun, Carlos A. Camargo Jr
Summary: This study describes the development and operation of a national network dedicated to surveillance of acute respiratory infections in emergency departments, providing a valuable public health resource for monitoring the epidemiology, viral causes, and outcomes of ED patients with ARIs.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2023)
Article
Virology
Yury A. Bochkov, Mark Devries, Kaitlin Tetreault, Ronald Gangnon, Sujin Lee, Leonard B. Bacharier, William W. Busse, Carlos A. Camargo, Timothy Choi, Robyn Cohen, Ramyani De, Gregory P. DeMuri, Anne M. Fitzpatrick, Peter J. Gergen, Kristine Grindle, Rebecca Gruchalla, Tina Hartert, Kohei Hasegawa, Gurjit K. Khurana Hershey, Patrick Holt, Kiara Homil, Tuomas Jartti, Meyer Kattan, Carolyn Kercsmar, Haejin Kim, Ingrid A. Laing, Peter N. Le Souef, Andrew H. Liu, David T. Mauger, Tressa Pappas, Shilpa J. Patel, Wanda Phipatanakul, Jacqueline Pongracic, Christine Seroogy, Peter D. Sly, Christopher Tisler, Ellen R. Wald, Robert Wood, Robert F. Lemanske, Daniel J. Jackson, James E. Gern
Summary: This study examined cross-neutralization reactions and antibody duration of rhinovirus type A (RV-A) and type C (RV-C). The results showed limited cross-neutralization reactions between the two types, which are limited to genetically similar strains. However, the duration of antibody response during childhood is similar for both types.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Multidisciplinary Sciences
Christopher L. Bennett, Allan S. Detsky, Carson E. Clay, Janice A. Espinola, Julie Parsonnet, Carlos A. Camargo
Summary: This study found that emergency departments (EDs) in HIV priority jurisdictions in the United States serve populations emphasized in HIV-related efforts, such as Black or African American or Hispanic or Latino populations, as well as communities with higher proportions uninsured and living in poverty, and higher rates of chlamydia, gonorrhea, and syphilis. EDs with teaching hospital affiliations had the highest visit volumes and steady growth. The findings suggest that geographically targeted screening in EDs with a teaching hospital affiliation could efficiently reach vulnerable populations and reduce the burden of undiagnosed HIV in the US.
Article
Cardiac & Cardiovascular Systems
Geneva D. Mehta, Anna Chen Arroyo, Zhaozhong Zhu, Janice A. Espinola, Jonathan M. Mansbach, Kohei Hasegawa, Carlos A. Camargo Jr
Summary: The history of severe bronchiolitis in infancy is associated with decreased lung function at the age of 6, potentially increasing the risk of chronic respiratory illnesses in the future.
RESPIRATORY MEDICINE
(2023)
Article
Health Care Sciences & Services
Kori S. Zachrison, Rebecca E. Cash, Krislyn M. Boggs, Emily M. Hayden, Ashley F. Sullivan, Carlos A. Camargo Jr
Summary: This study aimed to examine the use of telehealth by US emergency departments (EDs) during COVID-19 and whether existing telehealth infrastructure or increased system integration were associated with increased likelihood of use. The results showed that telehealth use by US EDs in 2020 exceeded expectations and preexisting telehealth infrastructure was associated with increased innovation in its use.
TELEMEDICINE AND E-HEALTH
(2023)