4.5 Article

Root Coverage Using Acellular Dermal Matrix and Comparing a Coronally Positioned Tunnel With and Without Platelet-Rich Plasma: A Pilot Study in Humans

期刊

JOURNAL OF PERIODONTOLOGY
卷 80, 期 3, 页码 397-404

出版社

WILEY
DOI: 10.1902/jop.2009.080438

关键词

Allograft; extracellular matrix; esthetic surgery; gingival recession; platelet-rich plasma

资金

  1. BioHorizons, Birmingham, Alabama

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Background: The primary aim of this randomized, controlled, blinded clinical pilot study was to compare the percentage of recession defect coverage obtained with a coronally positioned tunnel (CPT) plus an acellular dermal matrix allograft (ADM) to that of a CPT plus ADM and platelet-rich plasma (CPT/PRP) 4 months post-surgically. Methods: Eighteen patients with Miller Class I or 11 recession 3 mm at one site were treated and followed for 4 months. Nine patients received a CPT plus ADM and were considered the positive control group. The test group consisted of nine patients treated with a CPT plus ADM and PRP. Patients were randomly selected by a coin toss to receive the test or positive control treatment. Results: The mean recession at the initial examination for the CPT group was 3.6 +/- 1.0 mm, which was reduced to 1.0 +/- 1.0 mm at the 4-month examination for a gain of 2.6 +/- 1.5 mm or 70% defect coverage (P<0.05). The mean recession at the initial examination for the CPT/PRP group was 3.3 +/- 0.7 mm, which was reduced to 0.4 +/- 0.7 mm at the 4-month examination for a gain of 2.9 +/- 0.5 mm or 90% defect coverage (P <0.05). There were no statistically significant differences between the groups (P>0.05). Conclusions: The CPT plus ADM and PRP produced defect coverage of 90%, whereas the CPT with ADM produced only 70% defect coverage. This difference was not statistically significant, but it may be clinically significant. J Periodontol 2009; 80:397404.

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