Review
Pediatrics
Manuel Sanchez Luna, Sylvia Caballero Martin, Carmen Sanchez Gomez-de-Orgaz
Summary: The number of preterm infants is increasing globally, especially in low- and middle-income countries, posing challenges for neonatologists and milk banks to provide adequate nutrition for infant growth. While the benefits of mother's own milk are well recognized, the use of donor milk is common in NICUs. Utilizing donated milk that matches the composition of mother's milk can help protect premature infants from certain risks associated with prematurity.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Ahreen Allana, Kahmun Lo, Myra Batool, Ivan Hand
Summary: The use of donor human milk in preterm, very-low-birth-weight infants reduces the rate of necrotizing enterocolitis and promotes earlier initiation of enteral feeding and faster return to birth weight.
Review
Obstetrics & Gynecology
David H. Adamkin
Summary: Human milk is essential for the nutritional and anti-infective support of VLBW infants, but it alone is insufficient to meet their needs. The use of multicomponent fortifiers derived from cow's milk or solely from human milk has been beneficial in improving short-term growth. However, concerns regarding the association between cow's milk-based fortifiers and NEC exist. Different approaches, such as fixed dosage, adjustable fortification, and targeted fortification based on milk analysis, can be used for fortifying human milk.
JOURNAL OF PERINATOLOGY
(2023)
Article
Nutrition & Dietetics
Jolanta Lis-Kuberka, Marta Berghausen-Mazur, Magdalena Orczyk-Pawilowicz
Summary: The study found that gestational diabetes mellitus (GDM) does not have a significant impact on the immunological quality of early milk, and there are slight differences in lactoferrin and immunoglobulin concentrations between hyperglycemic and normoglycemic mothers.
Article
Food Science & Technology
Guangxu Ren, Guangyan Cheng, Jiaqi Wang
Summary: Although clinical observations suggest that children are less susceptible to SARS-CoV-2 infection than adults, there is still debate on the underlying mechanisms. Studies have shown that pediatric patients tend to have milder symptoms and lower mortality rates. Milk plays an important role in regulating homeostasis, especially in disease states.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Eva Kontopodi, Sertac Arslanoglu, Urszula Bernatowicz-Lojko, Enrico Bertino, Maria Enrica Bettinelli, Rachel Buffin, Tanya Cassidy, Ruurd M. van Elburg, Corina Gebauer, Anne Grovslien, Kasper Hettinga, Ioanna Ioannou, Daniel Klotz, Radmila Mileusnic-Milenovic, Guido E. Moro, Jean-Charles Picaud, Bernd Stahl, Gillian Weaver, Johannes B. van Goudoever, Aleksandra Wesolowska
Summary: The study reveals a wide variability in milk banking practices across Europe, including practices that could further enhance the efficiency of donor human milk banking. The findings could be used as a groundwork for a global discussion on the development of evidence-based guidelines to improve these practices.
Article
Food Science & Technology
Karina Jeanette Parra-Saavedra, Adriana Macaria Macias-Lamas, Jorge Manuel Silva-Jara, Josue Raymundo Solis-Pacheco, Pablo Cesar Ortiz-Lazareno, Blanca Rosa Aguilar-Uscanga
Summary: This study presents a method for obtaining lyophilized lactoferrin from breast milk, and quantifying it using HPLC. The results demonstrate that lyophilized lactoferrin has the ability to inhibit biofilm formation of Pseudomonas aeruginosa.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2022)
Article
Food Science & Technology
Juliana A. S. Leite, Randall C. Robinson, Jaime Salcedo, Juliana N. R. Ract, Virginia S. Quintal, Carmen C. Tadini, Daniela Barile
Summary: This study investigated the impact of microwave-assisted heating on the concentration of key biological compounds in donor human milk. Compared to low-temperature long-time pasteurization, microwave-assisted heating better preserved the concentration of immunoglobulins and lactoferrin, making it a promising alternative method for Human Milk Banks.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Stefano Lorenzetti, Torsten Ploesch, Inga C. Teller
Summary: Breastfeeding provides overall beneficial health to the mother-child dyad and is universally recognized as the preferred feeding mode for infants. This review discusses the environmental and dietary contaminants' effects on chemicals in human milk and focuses on the short- and long-term effects of these contaminants on the human body.
Article
Nutrition & Dietetics
Stacey R. Ramey, Stephanie Merlino Barr, Katie A. Moore, Sharon Groh-Wargo
Summary: Human milk analysis and individualized fortification are emerging practices within NICUs in the US. Few institutions are using it in the clinical setting with significant variability in execution and many logistical concerns regarding implementation. Future research may be beneficial to evaluate how practices change with the increasing popularity and use of HMA and individualized fortification in clinical settings.
FRONTIERS IN NUTRITION
(2021)
Article
Biology
Ikrame Aknouch, Adithya Sridhar, Eline Freeze, Francesca Paola Giugliano, Britt J. van Keulen, Michelle Romijn, Carlemi Calitz, Ines Garcia-Rodriguez, Lance Mulder, Manon E. Wildenberg, Vanesa Muncan, Marit J. van Gils, Johannes B. van Goudoever, Koert J. Stittelaar, Katja C. Wolthers, Dasja Pajkrt
Summary: Human milk has been found to inhibit the replication of SARS-CoV-2 and other enveloped viruses. Transcriptome analysis suggests that down-regulation of ATP1A1 may play a role in this antiviral activity.
LIFE SCIENCE ALLIANCE
(2022)
Article
Nutrition & Dietetics
Amy Gates, Amy B. Hair, Ariel A. Salas, Amy B. Thompson, Brian K. Stansfield
Summary: This study compared the nutrient content of commercial pooled donor human milk (DHM) with that of early and mature preterm human milk. The results showed that DHM had significantly lower protein, sodium, chloride, potassium, and zinc content compared to preterm human milk. However, there were no statistical differences in calorie, carbohydrate, calcium, phosphorus, magnesium, and vitamin D content between DHM and preterm human milk. These findings have important implications for designing human milk-based feeding plans.
JOURNAL OF NUTRITION
(2023)
Article
Endocrinology & Metabolism
U. Cucinotta, A. Gambadauro, F. Galletta, L. Cannavo, C. Cuppari, G. Ceravolo, C. Damiano, C. Paino, S. Sestito, I Rulli, E. Gitto
Summary: Although infection rates in neonatal intensive care units have decreased, neonatal sepsis remains a major cause of morbidity and mortality in newborns worldwide. The lack of a universally accepted definition and the variability in clinical presentation make diagnosis of neonatal sepsis challenging. This paper provides an updated overview of the etiology, clinical presentation, diagnosis, and treatment of neonatal sepsis.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Article
Medicine, General & Internal
Keisuke Nojiri, Satoshi Higurashi, Tomoki Takahashi, Yuta Tsujimori, Shunjiro Kobayashi, Yasuhiro Toba, Jun-ichi Yamamura, Kyoko Nomura, Hiroshi M. Ueno
Summary: The Japanese Human Milk Study aims to investigate how maternal health, nutritional status, lifestyle, and socio-demographic and economic factors influence breastfeeding practices and human milk composition, in order to determine factors affecting infant and child growth and development. The study enrolled 1122 Japanese lactating women, with findings showing that participants were generally healthier than the general population in Japan. Future plans include follow-up surveys for 12 months, analyzing macronutrient composition and bioactive factors in human milk, and investigating factors influencing breastfeeding practices and child development until children reach 5 years of age.
Article
Agriculture, Dairy & Animal Science
Veronica Carnicelli, Anna Rita Lizzi, Alessia Ponzi, Carla Luzi, Lisa Grotta, Francesca Bennato, Antonio Di Giulio
Summary: The study investigated the effectiveness of dairy products obtained from ewes fed with iodine-fortified diet in preventing iodine and iron deficiency. The results showed that these dairy products contain more bioactive compounds and are particularly suitable for the elderly.
JOURNAL OF DAIRY RESEARCH
(2021)
Article
Pediatrics
Paula G. Radmacher, Frank D. Groves, Joshua A. Owa, Gabriel E. Ofovwe, Emmanuel A. Amuabunos, Bolajoko O. Olusanya, Tina M. Slusher
Article
Pediatrics
Michael P. Sherman, David H. Adamkin, Victoria Niklas, Paula Radmacher, Jan Sherman, Fiona Wertheimer, Karel Petrak
JOURNAL OF PEDIATRICS
(2016)
Article
Chemistry, Organic
Paula G. Radmacher, Stephen W. Looney, Steven R. Myers
POLYCYCLIC AROMATIC COMPOUNDS
(2010)
