期刊
JOURNAL OF PERINATOLOGY
卷 31, 期 2, 页码 130-136出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/jp.2010.81
关键词
prematurity; behavior; assessment of preterm infants' behavior (APIB); neurological examination; EEG; Bayley Scales of Infant Development
资金
- National Institutes of Health (NIH) [RO1HD3826]
- US Department of Education [HO23C970032, R305T990294]
- Irving Harris Foundation, NIH [P30HD18655]
Objective: This study investigates the effectiveness of the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) on neurobehavioral and electrophysiological functioning of preterm infants with severe intrauterine growth restriction (IUGR). Study Design: Thirty IUGR infants, 28 to 33 weeks gestational age, randomized to standard care (control/C = 18), or NIDCAP (experimental/E = 12), were assessed at 2 weeks corrected age (2wCA) and 9 months corrected age (9mCA) in regard to health, anthropometrics, and neurobehavior, and additionally at 2wCA in regard to electrophysiology (EEG). Result: The two groups were comparable in health and anthropometrics at 2wCA and 9mCA. The E-group at 2wCA showed significantly better autonomic, motor, and self-regulation functioning, improved motility, intensity and response thresholds, and reduced EEG connectivity among several adjacent brain regions. At 9mCA, the E-group showed significantly better mental performance. Conclusion: This is the first study to show NIDCAP effectiveness for IUGR preterm infants. Journal of Perinatology (2011) 31, 130-136; doi:10.1038/jp.2010.81; published online 22 July 2010
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