Risk factors for macrosomia in infants born to Latina women

Objective: To assess risk factors for macrosomic infant birth among Latina women. Study Design: Prospective study of Latina women recruited during pregnancy from prenatal clinic at San Francisco General Hospital. Information was obtained through a structured interview and review of medical records. Result: A total of 11% of women delivered macrosomic infants (birth weight > 4000 g). In unadjusted analyses, significant risk factors for macrosomia included older maternal age, increasing gravidity, previous history of macrosomic birth and pre-pregnancy overweight. After adjusting for confounders using multivariate analyses, older mothers (10-year increments) had an elevated risk of macrosomia (odds ratio (OR) 2.59; 95% confidence interval (CI) 1.28 to 5.24). Conclusion: Efforts to reduce macrosomia in Latina women should focus on older mothers.