Article
Pediatrics
Tong Wu, Junwen Yang-Huang, Meike W. Vernooij, Maria Rodriguez-Ayllon, Vincent W. V. Jaddoe, Hein Raat, Stefan Klein, Edwin H. G. Oei
Summary: This study found that increasing daily physical activity by one hour was associated with lower fat mass and abdominal visceral fat mass, and higher lean body mass. On the other hand, increasing daily screen time by one hour was associated with higher body mass index, fat mass, abdominal subcutaneous and visceral fat mass.
Article
Multidisciplinary Sciences
Hiroki Higuchi, Yuko Okumura, Tessei Kobayashi
Summary: The study found that 32- to 48-month-olds directed their gaze at the target letter, while 32- to 40-month-olds could barely read the presented hiragana letters. This suggests that toddlers have already begun to grasp implicit letter-sound correspondences well before actually acquiring the ability to read letters.
SCIENTIFIC REPORTS
(2021)
Article
Food Science & Technology
Yanjun Zhou, Haixia Sui, Yibaina Wang, Ling Yong, Lei Zhang, Jiang Liang, Jing Zhou, Lili Xu, Yanxu Zhong, Jinyao Chen, Yan Song
Summary: A duplicate diet collection method was used to estimate dietary exposure to glutamates in children aged 2-5 years in selected provinces of China. Results showed that glutamates content was highest in mixed meals, followed by powdered formula and milk and dairy products. The total mean daily dietary exposure for subjects was below the recommended daily intake by regulatory authorities, indicating a low risk of glutamates exposure in this group.
Article
Public, Environmental & Occupational Health
Tadeja Volmut, Rado Pisot, Jurij Planinsec, Bostjan Simunic
Summary: Research on children's physical activity has found that during summer holidays, children's overall activity levels significantly decrease, with obesity status and physical fitness test results being associated with changes in activity levels. Thus, future studies and interventions should pay more attention to intervening in children's physical activity during summer holidays.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Pediatrics
Nuria Martin-Pozuelo, Veronica Robles-Garcia, Laura Piccardi, Alejandro Quintela del Rio, Javier Cudeiro, Isabel De las Cuevas-Teran
Summary: This study aims to determine whether adapted versions of the Walking Corsi Test (WalCT) can be used to test topographical memory in 2- and 3-year-old toddlers born at term and preterm. The results showed that both versions of the test were suitable for early ages and prematurity conditions, but the preterm group had lower performance.
FRONTIERS IN PEDIATRICS
(2023)
Article
Multidisciplinary Sciences
Chisa Tsuyuki, Koya Suzuki, Kanako Seo, Dandan Ke, Kyoko Tsuge, Pengyu Deng, Dajiang Lu, Hisashi Naito
Summary: Physical activity and sleep are important factors for children's mental and physical health, even at a very young age. Research shows that current physical activity directly impacts psychosocial health, while past physical activity indirectly affects girls’ psychosocial health through current physical activity. Additionally, past sleep quality has a slight impact on current psychosocial health, both indirectly through current sleep quality and directly.
SCIENTIFIC REPORTS
(2023)
Article
Nutrition & Dietetics
Prasangi Dabare, Pujitha Wickramasinghe, Indu Waidyatilaka, Sarita Devi, Anura V. V. Kurpad, Dulani Samaranayake, Maduka de Lanerolle-Dias, Rajitha Wickremasinghe, Andrew P. P. Hills, Pulani Lanerolle
Summary: This study aimed to develop a regression equation to predict physical activity energy expenditure (PAEE) using accelerometry. Children aged 11-13 years were recruited and randomly assigned to validation (n = 54) and cross-validation (n = 25) groups. The final prediction equation (PAEE = [0.001CPM] - 0.112) accounted for 70.6% of the variance and was found to be valid for use in Sri Lankan children.
Article
Clinical Neurology
Borge Sivertsen, Allison G. Harvey, Ted Reichborn-Kjennerud, Eivind Ystrom, Mari Hysing
Summary: The study examined the bidirectional association between sleep problems, internalizing problems, and depressive symptoms in toddlers and children aged 1.5 to 8 years, showing a link between sleep and internalizing/depressive symptoms from early childhood to middle childhood. Intervention studies are needed to investigate whether addressing these issues at an early age may prevent the onset of the other.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Endocrinology & Metabolism
Jani Liimatta, Christa E. Fluck, Aino Mantyselka, Merja R. Hakkinen, Seppo Auriola, Raimo Voutilainen, Jarmo Jaaskelainen, Timo A. Lakka
Summary: A 2-year lifestyle intervention study found that physical activity and dietary interventions can attenuate the increase of sexual maturation and androgen concentrations in normal-weight children.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Nursing
Augustine W. Kang, Kim M. Gans, Jared Minkel, Patricia Markham Risica
Summary: The study found that higher household income was associated with sleep variability and lower sedentary behavior in Latinx children, while higher sleepiness was related to lower moderate-to-vigorous physical activity (MVPA) and higher child BMI. MVPA levels were associated with higher sleep efficiency in this population.
JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES
(2021)
Article
Nutrition & Dietetics
Linnea Bergqvist-Noren, Emilia Hagman, Lijuan Xiu, Claude Marcus, Maria Hagstromer
Summary: This study examined longitudinal patterns and related factors of physical activity in young children aged 2 to 6. The findings showed that physical activity increased by an average of 11% per year, with children being more active on weekdays than on weekends. Maternal physical activity was significantly associated with child physical activity, while child sex, weight status, and socioeconomic status were not. These results highlight the importance of parental stimulation and intervention designs for weekends to promote physical activity in young children.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2022)
Article
Biochemistry & Molecular Biology
Bartlomiej K. Soltysik, Kamil Karolczak, Tomasz Kostka, Serena S. Stephenson, Cezary Watala, Joanna Kostka
Summary: Both acute exercise and regular physical activity have direct relationships with the redox system. However, data suggest both positive and negative relationships between physical activity and oxidation. The impact of physical activity on oxidative stress markers varies across platelets and plasma proteins, with protective effects observed for platelet lipid oxidation and pro-oxidative effects observed for platelet proteins.
Article
Orthopedics
Natalie A. Fini, Julie Bernhardt, Leonid Churilov, Rebecca Clark, Anne E. Holland
Summary: The study found associations between duration and bouts of MVPA and BMI, as well as between better gait speed, endurance, and cognition at baseline and higher MVPA and step count at 2 years.
News Item
Multidisciplinary Sciences
Ewen Callaway
Summary: Genetic material collected from permafrost reveals that northern Greenland was once a thriving forest.
Article
Oncology
Miriam Goette, Simon Basteck, Ronja Beller, Gabriele Gauss, Steffen Schmidt, Alexander Burchartz, Simon Kolb, May Grydeland, Dirk Reinhardt
Summary: This study investigated the differences in physical activity behaviors between childhood cancer survivors (CCS) and healthy peers. The results showed that CCS spent more time sedentary and less time in moderate-to-vigorous physical activity compared to their healthy peers. Among CCS aged 9-11 years, fewer of them met the international physical activity recommendations compared to the healthy cohort. Health conditions were found to be a predictor of whether individuals met the international physical activity recommendations.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Psychology, Developmental
D. G. M. Eijgermans, H. Raat, P. W. Jansen, E. Blok, M. H. J. Hillegers, W. Jansen
Summary: Approximately 15% of children in Western countries have emotional and behavioral problems. However, not all children receive the psychosocial care they need, especially children with a non-Western background. There is a significant association between teacher-reported problems and the use of psychosocial care, regardless of mother-reported problems. Ethnic background does not moderate this association.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Bente A. Smagge, Laura A. van der Velde, Jessica C. Kiefte-de Jong
Summary: There is a relationship between the food environment around primary schools in The Hague, The Netherlands, and childhood overweight, with schools in disadvantaged neighborhoods surrounded by more and closer fast-food outlets.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Joyce M. Molenaar, Inge C. Boesveld, Jessica C. Kiefte-de Jong, Jeroen N. Struijs
Summary: The Dutch Solid Start program aims to improve collaboration between the medical and social sectors to provide the best start in life for every child. This study developed an indicator set for local coalitions to monitor their Solid Start program. The indicator set includes 19 indicators covering the preconception, pregnancy, and after birth phases, and prioritizes social and medical topics such as poverty, psychological/psychiatric problems, and smoking. The development agenda identifies topics and indicators that lack data or clear operationalization.
INTERNATIONAL JOURNAL OF INTEGRATED CARE
(2022)
Article
Public, Environmental & Occupational Health
Irene N. Fierloos, Dafna A. Windhorst, Yuan Fang, Rienke Bannink, Marlinda Stam, Conny A. A. Slijkerman, Wilma Jansen, Hein Raat
Summary: This study examined the association between social support perceived by parents of children aged 1-7 years and the use of additional community youth health care services. The results showed that parents who perceived low to moderate levels of social support had higher odds of using additional youth health care services, especially among high educated parents.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Mirte Boelens, Hein Raat, Harrie Jonkman, Clemens M. H. Hosman, Denis Wiering, Wilma Jansen
Summary: The objective of this study was to evaluate a community-based program aimed at improving the health, safety, and talent development of youth and reducing socioeconomic inequalities. The study utilized a difference-in-difference design and involved two cross-sectional samples of 0- to 12-year-olds in the intervention and comparator conditions. The findings showed a significant intervention effect on outdoor-play, but no significant effects on other outcomes and no differences in intervention effects based on socioeconomic status.
SSM-POPULATION HEALTH
(2022)
Article
Public, Environmental & Occupational Health
J. M. Molenaar, L. van der Meer, L. C. M. Bertens, E. F. de Vries, A. J. M. Waelput, M. Knight, E. A. P. Steegers, J. C. Kiefte-de Jong, J. N. Struijs
Summary: This study aimed to identify classes of vulnerability among pregnant women in the Netherlands using pre-pregnancy data on social risk and protective factors, and validate these classes against adverse outcomes. The study found that vulnerability in pregnant women was characterized by high risk factors in a specific domain and protective factors in others. Furthermore, multidimensional vulnerability was associated with adverse outcomes such as premature birth and caesarean section.
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2023)
Article
Clinical Neurology
Yuan Fang, Amy van Grieken, Dafna A. Windhorst, Irene N. Fierloos, Harrie Jonkman, Clemens M. H. Hosman, Lu Wang, Matty R. Crone, Wilma Jansen, Hein Raat
Summary: This study investigated the prevalence, one-year development, and associated factors of dyssomnia in young children. The results showed that dyssomnia is common with a moderate persistent rate. Factors such as being a girl, having medical conditions, experiencing stressful life events, and lower parenting self-efficacy were found to be associated with the incidence and persistence of dyssomnia. Parental psychological distress was also identified as a factor for the persistence of dyssomnia in children.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Nutrition & Dietetics
Ezra Valido, Jivko Stoyanov, Frida Gorreja, Stevan Stojic, Christa Niehot, Jessica Kiefte-de Jong, Erand Llanaj, Taulant Muka, Marija Glisic
Summary: This systematic review examines the role of buckwheat in modifying gastrointestinal health outcomes and microbiomes. It found that buckwheat extracts have cytotoxic potential against human-derived GI cancer cell lines in preclinical studies, and animals fed with buckwheat had lower GI mucosal inflammation, higher alpha diversity in the GI microbiome, and higher levels of fecal short-chain fatty acids. However, human evidence remains limited, and further clinical trials are needed to determine its impact on human health.
Article
Nutrition & Dietetics
Alexandra P. M. de Koning-Backus, Jessica Kiefte-de C. Jong, Jeroen G. J. van Rooij, Andre G. G. Uitterlinden, Trudy A. Voortman, Magda Meester-Smoor, Caroline C. W. Klaver
Summary: Age-related macular degeneration (AMD) has a strong genetic basis, which can be reduced by environmental factors such as smoking and a healthy diet. However, many ophthalmologists do not inform patients about these beneficial lifestyle changes due to lack of trust and measurement methods. To address this, the AMD-Life study aims to investigate if personalized risk-profiling and coaching can motivate patients to change their lifestyle. The study also aims to identify biomarkers that reflect lifestyle changes beneficial for AMD.
Review
Pediatrics
Michel S. Smit, Mirte Boelens, Famke J. M. Molenberg, Hein Raat, Wilma Jansen
Summary: This systematic review and meta-analysis examined the long-term effects of primary school-based obesity prevention interventions on various outcomes. Despite including 19 studies, no significant long-term effects were found on body-mass index, waist circumference, and weight status. The evidence quality was assessed as moderate to very low. Further research and policy recommendations are discussed.
Article
Medicine, General & Internal
Annemieke Wargers, Judit Queral, Famke J. M. Moelenberg, Lucia Tarro, Christopher M. Elphick, Electra Kalogerakou, Alexandros Karagiannis, Elisabet Llaurado, Yannis Manios, Christina Mavrogianni, Claire Murray, Dimitris Vlachopoulos, Craig A. Williams, Wilma Jansen, Rosa Sola
Summary: The SEEDS project aims to improve the healthy lifestyles of adolescents, particularly boys and girls from deprived areas, by using citizen science to design and co-create interventions. This cluster randomized controlled trial will be conducted in four countries and will involve 720 adolescents aged 13-15 years. The findings will be disseminated through various channels and used to provide policy recommendations.
Article
Family Studies
D. G. M. Eijgermans, P. W. Jansen, A. M. Shuker, J. F. P. Heydelberg, H. Raat, W. Jansen
Summary: This study aimed to identify the reasons for children to receive mental health care and their associations with sociodemographic and mental health characteristics. The results showed that behavioral problems were the most common reason for mental health care use (36%), followed by life events and family problems (15%) and emotional problems (15%). No associations were found for the other reasons such as social problems, physical problems, cognitive developmental problems, and other problems with sociodemographic or mental health characteristics.
CHILDREN AND YOUTH SERVICES REVIEW
(2023)
Article
Public, Environmental & Occupational Health
Irene N. Fierloos, Dafna A. Windhorst, Yuan Fang, Clemens M. H. Hosman, Harrie Jonkman, Matty R. Crone, Wilma Jansen, Hein Raat
Summary: Perceived social support is associated with parenting self-efficacy. Parents who perceive lower social support tend to have lower parenting self-efficacy, while an increase in perceived social support is associated with an increase in parenting self-efficacy.
Article
Nutrition & Dietetics
Joelle E. Vergroesen, Eric F. Thee, Tosca O. E. de Crom, Jessica C. Kiefte-de Jong, Magda A. Meester-Smoor, Trudy Voortman, Caroline C. W. Klaver, Wishal D. Ramdas
Summary: This study assessed the impact of the inflammatory potential of diet on the incidence of cataract, age-related macular degeneration (AMD), and open-angle glaucoma (OAG). The results showed that a pro-inflammatory diet was associated with increased risks of cataract and AMD, with the neutrophil-lymphocyte ratio (NLR) possibly playing a role as a marker of subclinical inflammation.
CLINICAL NUTRITION
(2023)
Article
Pediatrics
Mirte Boelens, Michel S. Smit, Dafna A. Windhorst, Harrie J. Jonkman, Clemens M. H. Hosman, Hein Raat, Wilma Jansen
Summary: The study found that participation in organized leisure-time activities, both in sports and non-sports, among 4-12 year old children, is associated with a lower risk of mental health problems.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)
