☆ 4.6 Article

Effect of Nutritional Rehabilitation on Gastric Motility and Somatization in Adolescents with Anorexia

JOURNAL OF PEDIATRICS (2013)

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JOURNAL OF PEDIATRICS

卷 163, 期 3, 页码 867-+

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DOI: 10.1016/j.jpeds.2013.03.011

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Pediatrics

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Research Institute at Nationwide Children's Hospital, Columbus, Ohio

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Reagent

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Objective To examine gastric function, as well as the presence of somatic complaints, anxiety symptoms, and functional gastrointestinal disorders (FGIDs), in adolescents with anorexia nervosa (AN) before and after nutritional rehabilitation. Study design Sixteen females with AN and 22 healthy controls with similar demographic profiles were included. Gastric emptying (measured as residual gastric volume) and gastric accommodation (measured as postprandial antral diameter) were assessed with abdominal ultrasonography. Participants completed the Children's Somatization Inventory (CSI), the Screen for Child Anxiety-Related Emotional Disorders, and the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III version. All testing was repeated 3-4 months later. Results Body mass index in the AN group improved over time (P = .012). Fasting gastric parameters were similar in the 2 groups. Maximum postprandial antral diameter was significantly greater in controls compared with the AN group (P = .008). Only adolescents with AN demonstrated a significant increase in maximum postprandial diameter at repeat testing (P = .009). There was no difference in residual gastric volume between the 2 groups. Initial CSI scores were higher in adolescents with AN (P < .0001), including higher scores for nausea and abdominal pain. CSI scores were significantly lower in adolescents with AN (P = .035). Initial scores on the Screen for Child Anxiety-Related Emotional Disorders were significantly higher in adolescents with AN (P = .0005), but did not change over time. Adolescents with AN met significantly more criteria for FGIDs (P = .003). Conclusion Adolescents with AN have impaired gastric accommodation that improves after nutritional rehabilitation, have significantly more somatic complaints, and meet more criteria for anxiety disorders and FGIDs. After nutritional rehabilitation, somatization improves and FGIDs become less common, but symptoms of anxiety persist.

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The effect of COVID-19 pandemic on hospitalizations and disease characteristics of adolescents with anorexia nervosa

Lotem Goldberg, Adi Ziv, Yoav Vardi, Shai Hadas, Tarek Zuabi, Lital Yeshareem, Tomer Gur, Shelly Steinling, Oded Scheuerman, Yoel Levinsky

Summary: There was a significant increase in the number of adolescents hospitalized with anorexia nervosa (AN) during the first year of the COVID-19 pandemic, but disease characteristics were not more severe as compared to the previous years.

EUROPEAN JOURNAL OF PEDIATRICS (2022)