Article
Surgery
Saniea F. Majid, Farah A. Husain, Yong Choi, Sujata Gill, Bruce Schirmer, Matthew Kroh, Marina Kurian
Summary: This article presents the top 10 seminal articles regarding Roux-en-Y gastric bypass (RYGB), focusing on operative safety, outcomes, surgical technique, and physiologic changes after the procedure. These articles aim to enhance surgeons' understanding and mastery of RYGB surgery, supporting its widespread acceptance and use.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Michael O'Laughlin, Jorge Cornejo, Alba Zevallos, Alisa Coker, Michael Schweitzer, Gina Adrales, Christina Li, Raul Sebastian
Summary: Background: The rates of secondary bariatric surgery have increased, with sleeve gastrectomy to gastric bypass conversion being the most common. This study evaluates the outcomes of this conversion compared to primary Roux-en-Y gastric bypass (RYGB) surgery using MBSAQIP data. Methods: The study analyzed the data of patients who underwent sleeve gastrectomy to RYGB conversion and primary laparoscopic RYGB, matching them based on preoperative characteristics. Results: The analysis showed that the conversion from sleeve gastrectomy to RYGB was associated with higher readmissions, interventions, conversion to open surgery, longer hospital stay, and longer operative time compared to primary RYGB. However, there were no significant differences in mortality or rates of bariatric complications. Conclusion: The study concludes that conversion from sleeve gastrectomy to RYGB is a safe and feasible procedure with reasonable outcomes compared to primary RYGB.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Marta Guimaraes, Catarina Osorio, Diogo Silva, Rui F. Almeida, Antonio Reis, Samuel Cardoso, Sofia S. Pereira, Mariana P. Monteiro, Mario Nora
Summary: The study evaluated the long-term efficacy of Roux-en-Y Gastric Bypass (RYGB) surgery by assessing weight loss and comorbidity improvement in patients 10 years or more after the surgery. Results showed a significant decrease in body mass index (BMI) and successful comorbidity remission. Although a small proportion of patients required revision surgery for weight loss failure, RYGB was confirmed as an effective primary bariatric intervention.
Article
Surgery
Mauricio Gonzalez-Urquijo, David E. Hinojosa-Gonzalez, Ale Gibran Alam Gidi, Sofia Hurtado Arellano, Eduardo Flores-Villalba, Javier Rojas-Mendez
Summary: Revisional gastric bypass surgery for failed gastric banding patients showed higher complication rates compared to primary RYGB. Despite a greater postoperative weight increase in the revisional group at 12-month follow-up, the difference was not statistically significant. Changes in weight and BMI did not differ significantly between the two groups.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Medicine, General & Internal
Marita Salame, Noura Jawhar, Amanda Belluzzi, Mohammad Al-Kordi, Andrew C. Storm, Barham K. Abu Dayyeh, Omar M. Ghanem
Summary: Marginal ulcers (MU) are a potential complication following Roux-en-Y gastric bypass (RYGB) surgery, with an average prevalence of 4.6%. Early identification and prompt intervention are crucial to prevent further complications. MU is a complex condition influenced by factors such as smoking, Helicobacter pylori infection, NSAID use, and pouch size. Diagnosis is typically made through endoscopy, and treatment involves modifying risk factors and medical therapy with proton pump inhibitors. Surgical intervention may be necessary for complicated ulcers, while endoscopic procedures and vagotomy may be considered for recurrent or challenging cases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
May Al Nawas, Jelmer E. Oor, Lucas Goense, Stephanie F. M. Hosman, Erik J. R. J. van der Hoeven, Niels A. T. Wijffels, Wouter W. te Riele, Marijn Takkenberg, Marinus J. Wiezer, Wouter J. M. Derksen
Summary: This study analyzed the accuracy of abdominal CT in diagnosing IH following RYGB surgery, concluding that CT is a reliable imaging modality for the detection of IH and should be added to the diagnostic work-up for RYGB patients with abdominal pain suggestive of IH to improve patient selection for explorative surgery.
Article
Surgery
Samuel Hunter Dunn, Sanaa Tejani, Jaime P. Almandoz, Sarah E. Messiah, Jeffrey Schellinger, Elisa Morales Marroquin, Matthew Mathew, Jay Horton, Anna Tavakkoli
Summary: Transoral gastric outlet reduction (TORe) is a safe and effective treatment for post-prandial hypoglycemia and weight regain after Roux-en-Y gastric bypass (RYGB) in patients with symptoms refractory to medications and dietary changes.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Samuel Hunter Dunn, Sanaa Tejani, Jaime P. Almandoz, Sarah E. Messiah, Jeffrey Schellinger, Elisa Morales Marroquin, Matthew Mathew, Jay Horton, Anna Tavakkoli
Summary: TORe is a safe and effective treatment for patients with refractory symptoms of post-prandial hypoglycemia and weight regain after RYGB.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Antonio D'Urso, Michel Vix, Silvana Perretta, Mihaela Ignat, Louise Scheer, Didier Mutter
Summary: Roux-en-Y gastric bypass after sleeve gastrectomy is a safe and effective revisional procedure to manage weight regain, de novo GERD, complications, and improve comorbidities. The percentage of excess weight loss at 1, 3, and 5 years post-bypass depends on the indication for revision.
Review
Endocrinology & Metabolism
Maria Jose Luesma, Jose Fernando, Irene Cantarero, Pilar Lucea, Sonia Santander
Summary: The prevalence of obesity has been increasing rapidly in recent decades, making it one of the most impacting diseases on global health. It is a chronic disease associated with various comorbidities that result in a reduced life expectancy and quality of life. The treatment of obesity requires a multidisciplinary approach by a specialized medical team and can be done through conservative or surgical treatments. Vertical gastrectomy, mixed techniques, and gastric bypass are the most commonly used surgical techniques. The choice of technique should consider the characteristics of each patient and the surgical team's experience.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Surgery
Salvatore Docimo, Jie Yang, Xiaoyue Zhang, Aurora Pryor, Konstantinos Spaniolas
Summary: The study findings suggest that One Anastomosis Gastric Bypass (OAGB) has a similar early safety profile compared to Roux-en-Y Gastric Bypass (RYGB) and that concerns about perioperative risks should not deter its adoption. However, OAGB does not appear to have a significantly improved safety profile over RYGB.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Medicine, General & Internal
Gisele Florencio, Aglecio Souza, Elinton Chaim, Allan Santos, Louise Duran, Camila Carvalho, Sarah Monte Alegre
Summary: This study evaluated the phase angle (PhA) and sarcopenia in young individuals pre- and post-Roux-en-Y gastric bypass surgery. The results showed that the postoperative group had significantly lower PhA and higher resistance (R). Handgrip strength and gait speed were negatively correlated with R, hs-CRP, and leptin. Appendicular lean mass was negatively correlated with reactance and R. Overall, PhA and other components of bioelectrical impedance analysis were found to be correlated with sarcopenia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Lieke M. Koggel, Peter J. Wahab, Rob J. Robijn, Theo J. Aufenacker, Bart P. L. Witteman, Marcel J. M. Groenen, Jan M. Vrolijk
Summary: The study shows that LAERCP is an effective and relatively safe procedure for biliary diseases in patients with RYGB, with a high success rate and low rate of adverse events.
Article
Surgery
Maja Odovic, Daniel Clerc, Nicolas Demartines, Michel Suter
Summary: This study assessed the incidence, clinical presentation, risk factors, and management of early postoperative bleeding (POB) after laparoscopic Roux-en-Y gastric by-pass (RYGB). It found that while the incidence of POB is low, it is the most frequent postoperative complication after RYGB. Most cases can be managed conservatively, but surgical treatment is needed for patients with hemodynamic instability or signs of intestinal obstruction.
Article
Endocrinology & Metabolism
Marco Castellana, Filippo Procino, Elisa Biacchi, Roberta Zupo, Luisa Lampignano, Fabio Castellana, Rodolfo Sardone, Andrea Palermo, Roberto Cesareo, Pierpaolo Trimboli, Gianluigi Giannelli
Summary: This study compared the efficacy of RYGB and SG for T2D remission and found that RYGB had a higher chance of achieving remission at 1 year compared to SG, while only showing a significant difference in achieving broad criteria for remission at 5 years. No other differences were found between the two procedures.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Pediatrics
Jennifer Bruny, Thomas Inge, Michael Rannie, Shannon Acker, Glenn Levitt, Ethan Cumbler, David Brumbaugh
Summary: The creation of an online database with interactive dashboard has transformed surgical M&M into a systematic case review, greatly facilitating quality improvement efforts. This system increased event capture rate and provided novel practice performance feedback, resulting in process improvement projects and educational objectives based on trending data.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Surgery
Justin R. Ryder, Peixin Xu, Kristen J. Nadeau, Megan M. Kelsey, Changchun Xie, Todd Jenkins, Thomas H. Inge, Petter Bjornstad
Summary: A comparison of 30-year cardiovascular disease event risks in adolescents with type 2 diabetes and severe obesity undergoing different treatments revealed that metabolic bariatric surgery (MBS) can reduce the risk of cardiovascular events, while medical therapy may increase the risk among this population.
SURGERY FOR OBESITY AND RELATED DISEASES
(2021)
Article
Surgery
Jaime M. Moore, Jacqueline J. Glover, Brian M. Jackson, Curtis R. Coughlin, Megan M. Kelsey, Thomas H. Inge, Richard E. Boles
Summary: This article discusses the ethical considerations of using MBS in pediatrics and presents an ethical framework supporting the application of MBS in youth based on the principle of justice without automatic exclusions, including specific populations such as IDD patients and preadolescents. The study demonstrates the application of a novel framework for the ethical evaluation of youth seeking MBS and potential for use in other youth-focused MBS programs, with future steps including prospective data collection to test the framework's validity in the target population.
SURGERY FOR OBESITY AND RELATED DISEASES
(2021)
Article
Pediatrics
Jose Diaz-Miron, Sarah Ogle, Alex Kaizer, Shannon N. Acker, Kyle O. Rove, Thomas H. Inge
Summary: The study found that adoption of telemedicine was slow in surgical specialties before the COVID-19 pandemic, with both surgeons and caregivers reporting low prior experience. However, satisfaction with telemedicine during the pandemic was generally high. Surgeon age was inversely related to satisfaction with telemedicine, while higher income households reported higher audiovisual satisfaction with telemedicine.
PEDIATRIC SURGERY INTERNATIONAL
(2022)
Article
Medicine, General & Internal
Amy S. Shah, Michael A. Helmrath, Thomas H. Inge, Stavra A. Xanthakos, Megan M. Kelsey, Todd Jenkins, Andrew T. Trout, Lorna Browne, Kristen J. Nadeau
Summary: The study aims to compare the effectiveness of VSG with the current best medical treatment in reducing hyperglycaemia and diabetes comorbidities in youth with T2D. Additionally, it aims to improve understanding of the pancreatic and enterohepatic mechanisms by which MBS improves diabetes and associated comorbidities.
Article
Pediatrics
Sarah B. Ogle, Julie Ressalam, Christine M. Baugh, Eric G. Campbell, Megan M. Kelsey, Thomas H. Inge
Summary: This study found that a certain percentage of adolescents aged 13 to 18 are medically eligible for metabolic and bariatric surgery, but there are barriers to referral, especially for minorities, patients with public insurance, and those with multiple comorbidities.
Article
Cardiac & Cardiovascular Systems
Suzanne S. Summer, Todd Jenkins, Thomas Inge, Ranjan Deka, Jane C. Khoury
Summary: This study found that American adolescents have poor diet quality and low levels of physical activity, and about half of them suffer from metabolic syndrome. Abdominal obesity is significantly associated with the severity of metabolic syndrome, while diet and exercise habits are related to the development of metabolic syndrome.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Pediatrics
Lorraine Kelley-Quon, Eveline Shue, Rita Burke, Caitlin Smith, Karen Kling, Elaa Mahdi, Shadassa Ourshalimian, Michael Fenlon, Matthew Dellinger, Stephen B. Shew, Justin Lee, Benjamin Padilla, Thomas Inge, Jonathan Roach, Ahmed Marwan, Katie W. Russell, Romeo Ignacio, Elizabeth Fialkowski, Amar Nijagal, Cecilia Im, Kenneth S. Azarow, Daniel J. Ostlie, Kasper Wang
Summary: Early Kasai portoenterostomy at tertiary-level centers significantly increases likelihood for transplant-free survival among infants with biliary atresia. Within 1 year, most infants experience readmission, over half develop cholangitis, and a small percentage require reoperation.
PEDIATRIC SURGERY INTERNATIONAL
(2022)
Article
Endocrinology & Metabolism
Kristina M. Decker, Jennifer Reiter-Purtill, Carolina M. Bejarano, Andrea B. Goldschmidt, James E. Mitchell, Todd M. Jenkins, Michael Helmrath, Thomas H. Inge, Marc P. Michalsky, Meg H. Zeller
Summary: This study found that adolescent bariatric surgery appears to be beneficial for problematic eating and eating-related psychopathology. The results also suggest that clinical intervention related to problematic eating and associated psychosocial concerns may be needed for young adults with obesity, regardless of surgical status.
OBESITY SCIENCE & PRACTICE
(2022)
Article
Endocrinology & Metabolism
Sandeep Dhindsa, Husam Ghanim, Todd Jenkins, Thomas H. Inge, Carroll M. Harmon, Amit Ghoshal, Zengru Wu, Michael J. McPhaul, Farid Saad, Paresh Dandona
Summary: Bariatric surgery led to significant weight loss and an increase in testosterone concentrations in 34 obese adolescent males. The maximum weight loss was achieved at 24 months post-surgery. Prior to surgery, 73% of the participants had subnormal free testosterone levels, which decreased to 20% and 33% after 2 and 5 years, respectively.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2022)
Article
Surgery
Lorraine Kelley-Quon, Shadassa Ourshalimian, Justin Lee, Katie W. Russell, Karen Kling, Stephen B. Shew, Claudia Mueller, Aaron R. Jensen, Lan Vu, Benjamin Padilla, Daniel Ostlie, Caitlin Smith, Thomas Inge, Jonathan Roach, Romeo Ignacio, Katrine Lofberg, Stephanie Radu, Autumn Rohan, Kasper S. Wang
Summary: This study aimed to minimize opioid prescribing in children after appendectomy using Quality Improvement methodology. The results showed a significant decrease in opioid prescribing after the Quality Improvement intervention, without significant changes in emergency room visits or patient satisfaction.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Article
Surgery
Eric G. Campbell, Ahmed Alasmar, Rosa Lawrence, Marinda Kurpius-Brock, Matthew DeCamp, Alexandra Kovar, Jonathan Schoen, Thomas Inge, Megan M. Kelsey, Richard Boles, Scott Engel
Summary: This study suggests that the primary barriers to MBS for adolescents with severe obesity are related to a general lack of information about MBS, social stigma, and access issues related to costs.
SURGERY FOR OBESITY AND RELATED DISEASES
(2022)
Article
Pediatrics
Amy A. Rydin, Cameron Severn, Laura Pyle, Kathleen Dorris, Christina Chambers, Debra Stiller, Todd C. Hankinson, Thomas Inge, Matthew A. Haemer, David M. Mirsky, Jaime Moore, Megan M. Kelsey
Summary: Hypothalamic obesity is common in children with hypothalamic tumors. A clinical algorithm can help in the recognition and management of this condition, but further research is needed to develop effective treatment.
Editorial Material
Gastroenterology & Hepatology
Thomas H. Inge, Justin R. Ryder
Summary: Severe obesity in adolescents has negative effects on their health and quality of life. Currently, metabolic and bariatric surgery is the only effective intervention, but it is not widely utilized. Therefore, there is a need for vigorous research in this area to benefit adolescents with obesity.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2023)
Meeting Abstract
Gastroenterology & Hepatology
Shikha S. Sundaram, Miriam Ben Abdallah, Emily Cooper, Kristen Nadeau, Megan Kelsey, Ronald J. Sokol, Thomas H. Inge