Article
Oncology
Kelsey L. Corrigan, Alison Yoder, Brian De, Lilie Lin, Anuja Jhingran, Melissa M. Joyner, Patricia J. Eifel, Lauren E. Colbert, Karen H. Lu, Ann H. Klopp
Summary: This study aimed to evaluate the long-term survival of patients with recurrent or oligometastatic gynecological cancer (ROMGC) treated with radiation therapy (RT) and investigate their clinical characteristics. The study found that patients in the chemoradiation group had higher median disease-free survival (DFS) compared to those treated with RT alone. Further randomized studies are needed to identify the patients who would benefit the most.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Acoustics
F. Ciccarone, A. Biscione, F. Moro, D. Fischerova, L. Savelli, M. Munaretto, L. Jokubkiene, P. Sladkevicius, V Chiappa, R. Fruscio, D. Franchi, E. Epstein, D. Timmerman, W. Froyman, L. Valentin, G. Scambia, A. C. Testa
Summary: Ovarian carcinosarcoma is typically diagnosed in postmenopausal women and at an advanced stage. The most common ultrasound appearance is a large solid tumor with irregular margins, inhomogeneous echogenicity of the solid tissue, and cystic areas.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Nursing
Angela Tolotti, Loris Bonetti, Carla Pedrazzani, Monica Bianchi, Laura Moser, Nicola Pagnucci, Davide Sari, Dario Valcarenghi
Summary: Fatigue is a common symptom in cancer patients that is often underestimated in clinical practice. Patients reported feeling powerless and aggressive, while nurses' gestures provided reassurance. However, there are challenges in objectively assessing fatigue.
Article
Medicine, General & Internal
Ta-Wei Chu, Jing-Yun Jhao, Ta-Jen Lin, Tzu-Wei Lin, Chia-Lin Wang, Huan-Shuo Chang, Li-Chun Liu, Cheng-Chang Chang
Summary: The majority of participants in this study were found to have vitamin D deficiency or insufficiency, with significant associations between low serum vitamin D levels and gynecologic diseases such as abnormal Pap smear results, high-risk HPV infection, and dysmenorrhea. Even after controlling for age, serum vitamin D levels were still significantly associated with conditions like abnormal breast ultrasound, uterus ultrasound, and dysmenorrhea.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2021)
Review
Nutrition & Dietetics
Michael Barnish, Mahsa Sheikh, Andrew Scholey
Summary: Fatigue, characterized by lack of energy and endurance, is a common symptom in various conditions. Nutrients, such as vitamins and minerals, play essential roles in mitigating physical and mental fatigue. A review of existing literature showed significant benefits of nutrient supplementation on fatigue.
Review
Oncology
Ya-Bin Zhang, Xue-Mei Zhong, Ni Han, Huang Tang, Shui-Yu Wang, Wen-Xuan Lin
Summary: This study aimed to summarize the evidence regarding the effectiveness of exercise interventions in reducing cancer-related fatigue. A total of 46 systematic reviews were assessed, and it was found that exercise intervention can be effective in reducing cancer-related fatigue. However, the quality of the included reviews was generally low, highlighting the need for higher-quality studies in this area.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Nicolo Bizzarri, Vito Chiantera, Matteo Loverro, Giulio Sozzi, Emanuele Perrone, Salvatore Gueli Alletti, Barbara Costantini, Valerio Gallotta, Lucia Tortorella, Anna Fagotti, Francesco Fanfani, Alfredo Ercoli, Giovanni Scambia, Giuseppe Vizzielli
Summary: This study compared the disease-free survival, cancer-specific survival, and peri-operative morbidity between patients undergoing open and minimally invasive pelvic exenteration. The results showed no significant difference in survival rates and complications, but a higher intra-operative transfusion rate was seen in the open group.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2023)
Article
Oncology
Suguru Odajima, Toshiyuki Seki, Sayako Kato, Keisuke Tomita, Yuichi Shoburu, Eitaro Suzuki, Masataka Takenaka, Motoaki Saito, Hirokuni Takano, Kyosuke Yamada, Aikou Okamoto
Summary: Edoxaban has been found to be effective and safe for the treatment of gynecological cancer-associated thromboembolism. The study shows that there is no significant difference in recurrence rates or adverse events between edoxaban and vitamin K antagonist (VKA) treatment. Initial unfractionated heparin (UFH) therapy prior to administration of edoxaban may not be necessary for patients without pulmonary embolism (PE).
JOURNAL OF GYNECOLOGIC ONCOLOGY
(2022)
Article
Multidisciplinary Sciences
Christopher Burton, Helen Dawes, Simon G. Goodwill, Michael G. Thelwell, Caroline G. Dalton
Summary: People with Long Covid experience varying symptoms that change over time. This study found real-time associations between different symptoms and between symptoms and physical activity. Specifically, fatigue was correlated with pain, and cognitive difficulty was correlated with light-headedness. However, the correlation between symptoms and physical activity was inconsistent.
Article
Medicine, General & Internal
Leonard A. Jason, Chelsea Torres
Summary: Previous studies on myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) have mainly focused on White subjects, resulting in limited information about ethnic differences. This study examined a sample of 19 Black patients diagnosed with ME/CFS and compared them to White patients with ME/CFS and healthy controls. The findings suggest that there are few differences in symptoms between Black and White patients with ME/CFS. The implications of these findings are discussed.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Multidisciplinary Sciences
Luis Carlos Lopes-Junior, Taiani Ferrarini, Luciana Bicalho Cevolani Pires, Jonathan Grassi Rodrigues, Luciane Bresciani Salaroli, Karolini Zuqui Nunes
Summary: This article describes a research plan for a systematic review and meta-analysis on the prevalence, composition, severity, and predictors of cancer symptom clusters in adult cancer patients undergoing chemotherapy. The study aims to provide health professionals with a better understanding of symptom clusters in adult cancer patients to contribute to evidence-based therapeutic interventions and success in clinical practice.
Article
Oncology
Kohei Yamaguchi, Yoko Matsumoto, Ryo Suzuki, Haruka Nishida, Daiki Omata, Hirofumi Inaba, Asako Kukita, Michihiro Tanikawa, Kenbun Sone, Katsutoshi Oda, Yutaka Osuga, Kazuo Maruyama, Tomoyuki Fujii
Summary: Chemotherapy is essential for treating gynecological cancers, and delivering anticancer drugs effectively with minimal side effects is crucial. The use of lipid bubbles combined with ultrasound can help enhance the therapeutic effects of cytotoxic drugs, with cisplatin and pegylated liposomal doxorubicin showing significant benefits in this drug delivery system. Bevacizumab, on the other hand, did not show significant improvements when combined with the bubble ultrasound-mediated drug delivery system.
Article
Oncology
Ying-Wen Wang, Yu-Che Ou, Hao Lin, Kun-Siang Huang, Hung-Chun Fu, Chen-Hsuan Wu, Ying-Yi Chen, Szu-Wei Huang, Hung-Pin Tu, Ching-Chou Tsai
Summary: Cancer-related fatigue (CRF) is common in gynecological cancer patients and often goes unnoticed. This study aimed to explore the prevalence and clinical characteristics of CRF in these patients. The results showed that 77.9% of patients had received fatigue management, and a predictive model was developed to help identify high-risk patients.
Article
Sport Sciences
Todd W. Lyons, Rebekah Mannix, Ken Tang, Keith Owen Yeates, Gurinder Sangha, Emma C. M. Burns, Darcy Beer, Alexander S. Dubrovsky, Isabelle Gagnon, Jocelyn Gravel, Stephen B. Freedman, William Craig, Kathy Boutis, Martin H. Osmond, Gerard Gioia, Roger Zemek
Summary: This study aimed to assess the occurrence and clustering of post-concussive symptoms in children and identify distinct patient phenotypes based on symptom type and severity. The results showed that post-concussive symptoms occur in distinct clusters and five patient groups were identified based on symptom type and severity.
BRITISH JOURNAL OF SPORTS MEDICINE
(2022)
Review
Oncology
Annabelle Brennan, Donal Brennan, Margaret Rees, Martha Hickey
Summary: Gynecological cancers and their treatments can lead to menopausal symptoms, such as hot flashes and genitourinary symptoms. Patients may experience more severe symptoms compared to natural menopause. Early menopause may have long-term implications, including bone loss and increased cardiovascular risk.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Orthopedics
Victoria E. Salmon, Sarah Hewlett, Nicola E. Walsh, John R. Kirwan, Maria Morris, Marie Urban, Fiona Cramp
BMC MUSCULOSKELETAL DISORDERS
(2019)
Article
Hematology
Elizabeth Bradshaw, Carey McClellan, Paul Whybrow, Fiona Cramp
Review
Rheumatology
Fiona Cramp
Article
Rheumatology
Lorraine Harper, Catherine A. Hewitt, Ian Litchfield, Matthew D. Morgan, Dimitrios Chanouzas, Hollie K. Caulfield, Linda Coughlan, Caroline Dean, Kate Fletcher, Fiona Cramp, Sheila Greenfield, Natalie J. Ives, Sue Jowett, Shalela Kodabuckus, Sarah Tearne, Sukhwant Sehmi, Charlotte Edwardson, Nathan P. Dawkins, Amanda J. Daley
Summary: This study assessed the feasibility and acceptability of a behavioural-based physical activity intervention for fatigue self-management in AAV patients. While the intervention was found to be acceptable, modifications are needed in terms of recruitment and protocol adherence before a definitive trial can be conducted.
Article
Rehabilitation
Nicola Walsh, Louise Jones, Sonia Phillips, Rachel Thomas, Lang'o Odondi, Shea Palmer, Fiona Cramp, Jon Pollock, Mike Hurley
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2020)
Article
Oncology
Pauline Humphrey, Emma Dures, Peter Hoskin, Fiona Cramp
Summary: The online survey of UK brachytherapy centers revealed wide variability in scheduling, treatment duration, and holistic care. The findings highlight the importance of exploring women's experiences with different treatment regimes and anesthesia techniques to improve future clinical care.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Rheumatology
Keziah Austin, Emma Dures, Celia Almeida, Fiona Cramp, Catherine M. Guly, Catherine L. Hill, Elizabeth A. Hoon, Sarah Mackie, Anne O'Brien, Richard A. Watts, Joanna C. Robson
Summary: The study identified a range of barriers and facilitators to physical activity in giant cell arteritis (GCA) patients, including physical symptoms, perceptions of personal capability, negative perceptions of physical activity, and facilitators such as motivation from healthcare professionals and personal strategies like pacing and goal-setting. Future work could involve developing an intervention to support physical activity in GCA patients, potentially using a behavioral change framework and involving patients in the design process.
ARTHRITIS CARE & RESEARCH
(2022)
Article
Critical Care Medicine
Ema L. Swingwood, Willemke Stilma, Lyvonne N. Tume, Fiona Cramp, Sarah Voss, Jeremy Bewley, George Ntoumenopoulos, Marcus J. Schultz, Wilma Scholte Op Reimer, Frederique Paulus, Louise Rose
Summary: There is little consistency in the use and reporting of mechanical
insufflation-exsufflation (MI-E) in invasively ventilated critically ill adults, making it difficult to provide recommendations for best practices. The main indications for MI-E use were the presence of secretions and mucus plugging, while perceived contraindications were related to the use of high levels of positive pressure. The settings and reporting of MI-E were inconsistent, with only a few studies reporting adverse events.
Article
Medicine, General & Internal
Justin Jagosh, Hannah Stott, Serena Halls, Rachel Thomas, Cathy Liddiard, Margaret Cupples, Fiona Cramp, Paula Kersten, Dave Foster, Nicola E. Walsh
Summary: Realist evaluation is a methodology that assesses the effectiveness of complex interventions by developing and validating program theories. In rapidly changing environments, unpredictable forces need to be incorporated into the evaluation process to optimize program implementation. When studying rapidly changing health service delivery, initial program theories can be developed through creative thinking, empirical literature, and stakeholder consultation, and the causal impact of different components can be tested to improve the quality of evaluation outputs.
Article
Nursing
John Percival, Katharine Abbott, Theresa Allain, Rachel Bradley, Fiona Cramp, Jenny Donovan, Candy McCabe, Kyra Neubauer, Sabi Redwood, Nikki Cotterill
Summary: The aim of this study was to understand the experiences and perspectives of practitioners on continence training, and how to improve its implementation and engagement. Qualitative interviews were conducted with nursing, medical, and allied health practitioners in three hospitals. Data analysis was done thematically, using both manual methods and NVivo software. The study emphasizes the importance of authorizing and providing continence training in ways that reflect professional preferences and practical resource considerations to enhance its uptake and engagement.
Article
Rheumatology
Rachel Thomas, Alice Berry, Caroline Swales, Fiona Cramp
Summary: Successfully engaging in physical activity is important for people with Rheumatoid Arthritis (RA) in managing symptoms, resisting functional decline and maintaining health and independence. This study aimed to determine whether the broader RA population shares similar beliefs and strategies regarding physical activity to those who report successful engagement, in order to inform support for people with RA.
MUSCULOSKELETAL CARE
(2023)
Article
Medicine, General & Internal
Peter W. Gladwell, Fiona Cramp, Shea Palmer
Summary: There is currently a lack of high-quality evidence regarding the effectiveness of TENS for chronic musculoskeletal pain. Future research should focus on consensus-building regarding the content and delivery of TENS training, as well as the development of an effective and acceptable training course. Additional research is also needed to expand the evidence base for appropriate patient-reported outcomes in the context of TENS use.
MEDICINA-LITHUANIA
(2022)
Article
Rheumatology
Jennifer Pearson, Jessica Coggins, Erik Lenguerrand, Sandi Derham, Julie Russell, Nicola E. Walsh, Fiona Cramp
Summary: This study aims to explore the feasibility and acceptability of delivering the Fibromyalgia Self-Management Programme in a community setting, providing information for a future efficacy study. The research will involve recruiting 70 FM patients for a randomized controlled trial, with analysis based on patient-reported outcomes and health economic data.
MUSCULOSKELETAL CARE
(2021)
Article
Rheumatology
Fiona Cramp, Rachel Thomas, Anne M. Haase, Melissa Domaille, Sarah Manns, Caroline Swales, Judy Hurfurt, Nicola E. Walsh
MUSCULOSKELETAL CARE
(2020)
Article
Rheumatology
Jennifer Pearson, Katie Whale, Nicola E. Walsh, Sandi Derham, Julie Russell, Fiona Cramp
MUSCULOSKELETAL CARE
(2020)
