Review
Medicine, General & Internal
Lawko Ahmed, Anastasia Constantinidou, Andreas Chatzittofis
Summary: Precision medicine has advanced due to technological developments but has also brought forth ethical concerns and potential risks. This study aimed to explore patients' perspectives on these issues. The results revealed eight main concerns from patients, including privacy and security of patient data, economic impact, psychosocial harms, discrimination risks, informed consent risks, mistrust in providers and research, diagnostic accuracy, and changes in the doctor-patient relationship. It is crucial to address these ethical issues and risks through patient education, dedicated research, and official policies.
FRONTIERS IN MEDICINE
(2023)
Article
Health Care Sciences & Services
Van Thu Nguyen, Philippe Ravaud, Viet Thi Tran, Bridget Young, Isabelle Boutron
Summary: The study investigates patients' preferences for the organization of randomized controlled trials (RCTs) and finds that most patients prefer a hybrid model involving both on-site and remote visits. Patients are more likely to participate in a trial organized according to their preferences.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Clinical Neurology
Crystal J. J. Yeo, Zachary Simmons, Darryl C. De Vivo, Basil T. Darras
Summary: Three innovative therapies for treating spinal muscular atrophy (SMA) since 2016 have shown remarkable improvements in infants and children, but the benefits for adults are limited and the treatments are not curative. Concerns have been raised regarding the high costs of these medications, the burden on taxpayers, and the societal costs of withholding treatments. Physicians should carefully consider the costs, benefits, quality of life implications, and ethical principles when making decisions for their patients.
ANNALS OF NEUROLOGY
(2022)
Article
Computer Science, Information Systems
Sidharth Quamara, Awadhesh Kumar Singh
Summary: This article systematically examines the security concerns associated with cryptocurrencies from various perspectives, including consensus mechanisms, applications, literature contributions, and ongoing projects worldwide. It also outlines challenges and provides insights for future research directions in the field.
COMPUTERS & SECURITY
(2022)
Article
Medicine, General & Internal
Banaz Jalil, Abdallah Y. Naser, Jose M. Prieto, Michael Heinrich
Summary: This study explored the perspectives and knowledge of Jordanian community pharmacists regarding herbal medicines. The results showed that there are some key concerns regarding recommendations, awareness, and reporting of herbal medicines among pharmacists. It is necessary to enhance education in order to provide objective and evidence-based information on the benefits and risks of herbal medicines.
Article
Pediatrics
Franco A. Carnevale, Alberto Giannini, Amabile Bonaldi, Elena Bravi, Costanza Cecchi, Andrea Pettenazzo, Angela Amigoni, Silvia Maria Modesta Pulitano, Chiara Tosin, Paolo Biban
Summary: This study investigates the decision-making process of life-sustaining treatment (LST) in pediatric intensive care units in Italy, identifying problematic ethical concerns faced by physicians and nurses, such as the absence of legislative standards for LST withdrawal. Physicians and nurses have differing views on how LST decisions should be made, highlighting the need for improved team processes and Italian LST decision-making standards.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Health Care Sciences & Services
Brinnae Bent, Ida Sim, Jessilyn P. Dunn
Summary: The field of digital medicine has seen rapid growth, but interoperability has emerged as a critical barrier. Digital medicine professionals come from diverse educational backgrounds and use a variety of sensors and file types; the most commonly used sensors are those measuring physical activity and the cardiovascular system, with smartphones being the dominant source of digital health information collection in the digital medicine community.
JMIR MHEALTH AND UHEALTH
(2021)
Article
Cell Biology
Lulu Ding, Zhenyu Xiao, Xia Gong, Yaojin Peng
Summary: This study comprehensively analyzed the status quo of ethical concerns regarding cerebral organoids using knowledge graphs and statistical analysis. The findings revealed three main categories of ethical issues related to cerebral organoids, namely those common in life sciences, specific to cerebral organoids, and present in cross-fields. The study suggests that future research should focus on ethical concerns of consciousness, cross-fields, and the construction and improvement of regulatory systems.
CELL PROLIFERATION
(2022)
Article
Anesthesiology
Kevin T. Liou, Connie Chen, Nicholas Emard, Kathleen A. Lynch, Yen Nien Hou, Jun J. Mao
Summary: This study examines the characteristics, experiences, and perspectives of cancer patients who were prescribed an herbal topical analgesic for pain management. Most patients reported that the herbal topical analgesic improved their pain and health-related outcomes, was convenient to use, and addressed pain management needs that were not fulfilled by oral analgesics.
Article
Education & Educational Research
Roxana Naderi, Tyson A. Oberndorfer, Sarah R. Jordan, Blythe Dollar, Ethan U. Cumbler, Christine D. Jones
Summary: A qualitative study on the value of TEAM calls for internal medicine residents rotating on the ACE unit revealed three key themes: awareness of patient social complexities, bridging communication gaps across healthcare settings, and recognizing the value of other disciplines during transitions. Educators can enhance the educational value of interdisciplinary conference calls by promoting reflective debriefs and addressing previously unrecognized knowledge gaps.
BMC MEDICAL EDUCATION
(2021)
Article
Ethics
Naomi Jacobs, Jenneke Evers
Summary: Femtech is a term for technologies that cater to the health needs of women, providing digital solutions for tracking periods, managing fertility, and supporting pregnancy. However, ethical concerns arise regarding the reliability of medical information, privacy issues, and gender stereotypes. Capability Sensitive Design, a new framework for health technology, offers a way to address these concerns and create morally sensitive femtech.
Review
Pharmacology & Pharmacy
Marta Bryk, Elzbieta Karnas, Jakub Mlost, Ewa Zuba-Surma, Katarzyna Starowicz
Summary: MSCs, as multipotent progenitor cells derived from mesoderm, have been extensively studied for their regenerative properties, including the release of EVs which play a role in their functions. They regulate various processes in target cells and show potential applications in pain treatment and other diseases.
BRITISH JOURNAL OF PHARMACOLOGY
(2022)
Article
Oncology
Paolo Bossi, Andrea Antonuzzo, Grazia Armento, Francesca Consoli, Jacopo Giuliani, Raffaele Giusti, Maurizio Lucchesi, Aurora Mirabile, Loredana Palermo, Sarah Scagliarini
Summary: The study found that diagnosis inaccuracies, inappropriate treatments, and lack of monitoring are common issues in the clinical management of cancer pain. A corrective actions list based on pain characteristics was generated by the scientific board, highlighting the need for better education and training for oncologists. Physicians should be aware of current guideline recommendations and available pharmacological tools for BTcP.
CANCER MANAGEMENT AND RESEARCH
(2021)
Article
Health Care Sciences & Services
Joel Perrin, Nina Streeck, Rahel Naef, Michael Rufer, Simon Peng-Keller, Horst Rettke
Summary: There are similarities and differences in the perspectives of chronic pain patients and healthcare professionals regarding the integration of spiritual care into treatment. Patients emphasize the importance of recognizing their overall human integrity, including the spiritual dimension, while healthcare professionals express difficulties in addressing spiritual concerns. Both parties see a need for greater awareness and training in addressing the spiritual dimension in therapeutic interactions.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Medicine, General & Internal
Hye Chang Rhim, Adam Tenforde, Lisa Mohr, Karsten Hollander, Lutz Vogt, David A. Groneberg, Jan Wilke
Summary: Engaging in 300-450 minutes of physical activity per week is associated with lower odds of musculoskeletal pain in six body locations, while excessive doses of physical activity are associated with higher odds of pain in certain body locations.