Article
Food Science & Technology
Ishwari Gyawali, Guilian Zhou, Guli Xu, Genghui Li, Yujun Wang, Yuxian Zeng, Jincheng Li, Jingjing Zhou, Canjun Zhu, Gang Shu, Qingyan Jiang
Summary: Encapsulation can protect probiotics from environmental factors, improving survivability in the small intestine. In mice, microencapsulated probiotics increased fecal moisture, villus height to crypt depth ratio, intestinal mucin and sIgA concentration, MUC-2 and tight junction protein mRNA expression levels. It also reduced proinflammatory factor mRNA expression and increased anti-inflammatory factor mRNA expression. Furthermore, microencapsulated probiotics improved microbiota composition, fecal metabolites, and antioxidant capacity.
FOOD SCIENCE & NUTRITION
(2023)
Review
Nutrition & Dietetics
Monica Cerutti Martellet, Fernanda Majolo, Rodrigo Gay Ducati, Claucia Fernanda Volken de Souza, Marcia Ines Goettert
Summary: This article highlights the importance of using probiotics associated with fibers from Psyllium as prebiotics to maintain a healthy intestinal microbiota. The combination has the potential to remedy imbalances in gastrointestinal tract diseases by reducing the adhesion of pathogenic microorganisms. Coating technologies and encapsulating materials can increase the survival rate of these strains in the gastrointestinal tract.
Review
Biochemistry & Molecular Biology
Pawel Serek, Monika Oleksy-Wawrzyniak
Summary: The intestinal barrier, composed of cells, mucus, and microbiota, plays a crucial role in maintaining immune homeostasis. Disturbances in its tightness can lead to a range of issues, including systemic infections and autoimmune diseases. Zonulin, a protein found in epithelial cells, plays a key regulatory role.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nutrition & Dietetics
Kaibin Mo, Jing Li, Fenfen Liu, Ying Xu, Xianhui Huang, Hengjia Ni
Summary: This study found that 100 mg/kg MEEOs can help reduce the diarrhea index of weaning piglets, alleviate intestinal oxidative stress and inflammation, and maintain intestinal health, making it a recommended health promoter in piglets during the weaning period.
FRONTIERS IN NUTRITION
(2022)
Review
Pharmacology & Pharmacy
Enzo Spisni, Silvia Turroni, Patrizia Alvisi, Renato Spigarelli, Demetrio Azzinnari, Dario Ayala, Veronica Imbesi, Maria Chiara Valerii
Summary: There is increasing interest in the pharmaceutical industry regarding the human intestinal microbiota due to its association with non-communicable diseases. While probiotics and prebiotics have been explored for modulating the gut microbiota, this review highlights other potential interventions such as postbiotics, essential oils, fungus, and officinal plants. Further research, especially clinical studies using fungus, officinal and aromatic plants or their extracts, is necessary to fully understand and harness the potential of these interventions in modulating the intestinal microbiota for improved pharmacological therapy of non-communicable diseases.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Food Science & Technology
Thaiane Marques da Silva, Vandre Sonza Pinto, Vitor Ramires Fonseca Soares, Debora Marotz, Alexandre Jose Cichoski, Leila Queiroz Zepka, Eduardo Jacob Lopes, Cristiane de Bona da Silva, Cristiano Ragagnin de Menezes
Summary: This study aimed to produce microcapsules containing Lactobacillus acidophilus LA-02 using complex coacervation and transglutaminase crosslinking, assess their viability in different fruit juices, and their effect on the juices during storage. Orange juice was found to be the most suitable for probiotic addition, with the microcapsules providing protection for L. acidophilus and ensuring its survival. The crosslinking process was effective, promising probiotic viability in the fruit juices for up to 63 days.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Food Science & Technology
Liya Mei, Ying Chen, Jialiang Wang, Jian Lu, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen
Summary: This study aimed to explore the effect of different strains of Lactobacillus fermentum on IgA secretion from intestinal mucosa, and found that different strains have different stimulating effects. Additionally, it was speculated that different strains may stimulate IgA production through non-inflammatory pathways.
Article
Microbiology
Emily Pope, Bradley Haltli, Russell G. Kerr, Ali Ahmadi
Summary: Microencapsulation of bacteria is a promising cultivation technique for previously unculturable microbial species. Lowering the encapsulation temperature and adding nutrients significantly improve the viability and metabolic activity of marine bacteria. Therefore, the use of low-gelling-temperature agarose with supplemental nutrients is recommended for encapsulating marine bacteria obtained from temperate habitats.
Article
Biochemistry & Molecular Biology
Lei Liu, Shuyu Guo, Xing Chen, Shuhui Yang, Xi Deng, Mingxia Tu, Yufei Tao, Wenliang Xiang, Yu Rao
Summary: This study found that biofilm probiotics have better performance in immune modulation and microbiota composition, and are more active in amino acid and carbohydrate metabolism. Through the production of various metabolites, they may impact the host's intestinal microbiome and immune activity.
Article
Biotechnology & Applied Microbiology
Gulsun Ozyurt, Leyla Uslu, Mustafa Durmus, Yetkin Sakarya, Turkan Uzlasir, Esmeray Kuley
Summary: Spirulina fermented by LAB is an innovative fermented product with bioactive properties, and fermentation has a significant impact on its nutritional components. Microencapsulation with different ratios of coating material resulted in changes in nutritional components, color, and morphological appearances of unfermented and fermented Spirulina. Microencapsulation of fermented Spirulina has significant potential for the production of new functional foods.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Bin Wang, Xuheng Chen, Zhiyuan Chen, Huiwen Xiao, Jiali Dong, Yuan Li, Xiaozhou Zeng, Jinjian Liu, Guoyun Wan, Saijun Fan, Ming Cui
Summary: In this study, the researchers found that stable colonization of live A. muciniphila at lesion sites is essential for its anti-inflammatory function. They also developed a modified A. muciniphila that had enhanced inflammation targeting and intestinal colonization under an external magnetic field, leading to improved therapeutic efficacy against intestinal diseases. The findings further revealed that this modified A. muciniphila could drive M2 macrophage polarization by upregulating the protein level of IL-4 at inflammatory loci. These results demonstrate the importance of A. muciniphila in treating intestinal diseases.
EXPERIMENTAL AND MOLECULAR MEDICINE
(2023)
Article
Agriculture, Multidisciplinary
Tonghao Du, Zhanggen Liu, Qianqian Guan, Tao Xiong, Fei Peng
Summary: This study investigates the effects of soy protein isolate (SPI)-xylose conjugates heated at different times on the viability and stability of probiotics. The results show that SPI-xylose Maillard reaction products can improve bacterial survivability during spray drying and enhance bacterial gastrointestinal digestion resistance, making it a promising wall material for probiotic microencapsulation. This study sheds light on preparing probiotic microcapsules with superior properties.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Multidisciplinary Sciences
Milan Feher, Peter Fauszt, Emese Tolnai, Gabor Fidler, Georgina Pesti-Asboth, Aniko Stagel, Istvan Szucs, Sandor Biro, Judit Remenyik, Melinda Paholcsek, Laszlo Stundl
Summary: This study explored the effects of phytonutrient-induced changes in the gastrointestinal tract microbiota of common carp, finding that the dietary supplements improved community diversity, increased beneficial bacteria such as Clostridium and Lactobacillus, and decreased potentially pathogenic bacteria. The growth performance of common carp juveniles was not significantly affected by the supplementation of phytonutrients in the basal diet.
Article
Biotechnology & Applied Microbiology
Wenzhen Yuan, Xingpeng Xiao, Xuan Yu, Fuquan Xie, Pengya Feng, Kamran Malik, Jingyuan Wu, Ze Ye, Peng Zhang, Xiangkai Li
Summary: The study showed that oxaliplatin treatment can alter the gut microbiota, and probiotics can help alleviate the damage caused by oxaliplatin to the intestines.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Review
Microbiology
J. E. Vazquez Bucheli, S. D. Todorov, W. H. Holzapfel
Summary: Intestinal bowel disease (IBD) is a chronic immune-mediated clinical condition that is associated with microbial imbalances in the gut. Probiotics may be beneficial in preventing and treating this disease.
BENEFICIAL MICROBES
(2022)
Review
Biochemistry & Molecular Biology
Cristina Airoldi, Barbara La Ferla, Giuseppe D'Orazio, Carlotta Ciaramelli, Alessandro Palmioli
CURRENT MEDICINAL CHEMISTRY
(2018)
Article
Biochemistry & Molecular Biology
Alessandro Palmioli, Sara Bertuzzi, Ada De Luigi, Laura Colombo, Barbara La Ferla, Mario Salmona, Ivano De Noni, Cristina Airoldi
BIOORGANIC CHEMISTRY
(2019)
Correction
Biotechnology & Applied Microbiology
Valerio Mezzasalma, Enrico Manfrini, Emanuele Ferri, Anna Sandionigi, Barbara La Ferla, Irene Schiano, Angela Michelotti, Vincenzo Nobile, Massimo Labra, Patrizia Di Gennaro
BIOMED RESEARCH INTERNATIONAL
(2019)
Article
Polymer Science
Giuseppe D'Orazio, Alessandra De Giani, Jessica Zampolli, Zahraa Zeaiter, Patrizia Di Gennaro, Barbara La Ferla
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2019)
Review
Biochemistry & Molecular Biology
Mattia Vacchini, Rana Edwards, Roberto Guizzardi, Alessandro Palmioli, Carlotta Ciaramelli, Alice Paiotta, Cristina Airoldi, Barbara La Ferla, Laura Cipolla
CURRENT MEDICINAL CHEMISTRY
(2019)
Article
Nanoscience & Nanotechnology
Paola Allavena, Alessandro Palmioli, Roberta Avigni, Marina Sironi, Barbara La Ferla, Akihiro Maeda
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Francesca Ricciardiello, Yang Gang, Roberta Palorini, Quanxiao Li, Marco Giampa, Fangyu Zhao, Lei You, Barbara La Ferla, Humberto De Vitto, Wenfang Guan, Jin Gu, Taiping Zhang, Yupei Zhao, Ferdinando Chiaradonna
Review
Chemistry, Organic
Barbara La Ferla, Giuseppe D'Orazio
Summary: This review focuses on synthetic strategies for pyranoid spirofused sugar derivatives, with an emphasis on the most explored compounds possessing the spirofused structures at position C1 of the pyranoid scaffold. These structures are found to have the most relevant enzymatic inhibitor activities among the derivatives, while efforts have also been made to introduce spirofused entities at other positions for the preparation of biologically active compounds and chiral auxiliaries.
CURRENT ORGANIC SYNTHESIS
(2021)
Article
Biotechnology & Applied Microbiology
Luca Zoia, Annalisa Morelli, Laura Talamini, Martina B. Violatto, Arianna B. Lovati, Silvia Lopa, Camilla Recordati, Chiara Toffanin, Anika Salanti, Luca Russo, Laura Colombo, Matteo Moretti, Mario Salmona, Barbara La Ferla, Paolo Bigini
Article
Electrochemistry
Barbara Vercelli, Riccardo Donnini, Francesco Ghezzi, Antonio Sansonetti, Umberto Giovanella, Barbara La Ferla
Summary: This study investigates how different types of nitrogen centers in N-CDs affect their electrochemical and optical properties, shedding light on their redox mechanisms and pH sensitivity. The oxidation and reduction processes of N-CDs involve various nitrogen centers, with the pH dependence playing a crucial role in their responses.
ELECTROCHIMICA ACTA
(2021)
Article
Biochemistry & Molecular Biology
Francesco Ghezzi, Riccardo Donnini, Antonio Sansonetti, Umberto Giovanella, Barbara La Ferla, Barbara Vercelli
Summary: Understanding the influence of post-synthesis treatments on the properties of carbon quantum dots (CDs) is crucial for their use in biosensors. In this study, we investigated the effects of post-synthesis thermal treatments on Nitrogen-doped CDs (N-CDs) used in biosensors. The thermal treatments showed an oxidizing effect on graphitic N-atoms in the CDs, leading to partially oxidized mixed valence state systems and further oxidation into graphitic N-oxide forms. Additionally, the thermal treatments caused the decomposition of external ammonium ions in the CDs, resulting in protonation of pyridinic N-atoms and quenching of photoluminescence (PL) emission.
Article
Chemistry, Multidisciplinary
Barbara La Ferla, Barbara Vercelli
Summary: The controllable synthesis of red-emitting carbon quantum dots (r-CDs) is of fundamental importance for their application in advanced medical large-scale applications. In this study, we present an experimental investigation on the synthesis and post-synthesis purification treatments of r-CDs. We propose three synthetic strategies and observe challenges in the efficiency, yield, and separation of r-CDs using different precursors.
Proceedings Paper
Nanoscience & Nanotechnology
Barbara La Ferla, Luca Zoia, Paolo Bigini, Patrizia Di Gennaro
NANOINNOVATION 2017
(2018)