期刊
JOURNAL OF ORTHOPAEDIC RESEARCH
卷 30, 期 12, 页码 1945-1951出版社
WILEY
DOI: 10.1002/jor.22156
关键词
anti-inflammatory drugs; LLLT; phototherapy; tendon; biomechanics
类别
资金
- FAPESP [2009/02117-5]
NSAIDs are widely prescribed and used over the years to treat tendon injuries despite its well-known long-term side effects. In the last years several animal and human trials have shown that low-level laser therapy (LLLT) presents modulatory effects on inflammatory markers, however the mechanisms involved are not fully understood. The aim of this study was to evaluate the short-term effects of LLLT or sodium diclofenac treatments on biochemical markers and biomechanical properties of inflamed Achilles tendons. Wistar rats Achilles tendons (n?=?6/group) were injected with saline (control) or collagenase at peritendinous area of Achilles tendons. After 1?h animals were treated with two different doses of LLLT (810?nm, 1 and 3?J) at the sites of the injections, or with intramuscular sodium diclofenac. Regarding biochemical analyses, LLLT significantly decreased (p?
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