Article
Chemistry, Physical
Sambasivarao Kotha, Deepshikha Singh
Summary: In this paper, three simple methods for the synthesis of pyrrole derivatives starting with commercially available amines were reported. The first method achieved one-pot ring closing metathesis (RCM) and aromatization sequence using Grubbs first-generation catalyst (G-I), without the use of any additional reagents. The second and third methods relied on the condensation of 2,5-hexanedione/2,5-dimethoxy tetrahydrofuran in the presence of a low melting mixture of N, N'-dimethylurea (DMU) and L-(+)-tartaric acid (TA) and glacial acetic acid, resulting in substituted pyrroles with excellent yield. The photophysical properties of these molecules were also studied by fluorescence spectroscopic data, showing good quantum yield (OF).
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Raziyeh Keshavarz, Mahnaz Farahi, Bahador Karami, Parisa Gheibipour, Ali Zarnegaryan
Summary: A heterogeneous catalyst with a high contact surface, excellent performance, and recyclability was successfully prepared using graphene oxide as a support. The catalyst showed satisfactory performance in the synthesis of pyrroles and could be easily recovered and reused.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Asieh Azhdari, Najmedin Azizi, Haleh Sanaeishoar, Elham Tahanpesar
Summary: A novel heterogeneous acidic catalyst was prepared by immobilizing amidosulfonic acid on graphitic carbon nitride, leading to a unique solid acid structure that enhanced catalytic activity for the high efficient preparation of pyrroles. The catalyst showed good to excellent yields with simple purification and maintained its activity after multiple cycles.
MONATSHEFTE FUR CHEMIE
(2021)
Article
Chemistry, Organic
Sachin B. Wagh, Vladimir Maslivetc, James J. La Clair, Alexander Kornienko
Summary: Recent studies have discovered the ability of human prostaglandin-endoperoxide synthase 2 (COX-2) to guide the formation of fluorescent pyrroles through a specific reaction, leading to the identification of a central motif. Further exploration of this motif has resulted in the design of COX2 inhibitors with comparable activity to the orally prescribed nonsteroidal anti-inflammatory COX-2 inhibitor Celecoxib. Additionally, important structure-activity relationship (SAR) data for the discovery of COX-2 inhibitors has been obtained.
Article
Chemistry, Multidisciplinary
Pablo Gonzalez Cortes, Rodrigo Araya-Hermosilla, Kerry Wrighton-Araneda, Diego Cortes-Arriagada, Francesco Picchioni, Feng Yan, Petra Rudolf, Ranjita K. Bose, Franck Quero
Summary: The thermal properties of polymers depend on their chemical structure and intermolecular forces. By chemically modifying polyketones and increasing the amount of supramolecular interactions, the glass transition temperature of polyketones can be tuned. The research shows that modification with aminomethyl benzoic acid and aminohexanoic acid introduces new hydrogen bonding possibilities and significantly increases the glass transition temperature, while modification with an imidazole derivative introduces new and stronger pi-pi interactions.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Chemistry, Physical
Yahao Dong, Zhangquan Zhou, Yanan Wang, Xinjuan Li, Tao Li, Yihang Ren, Wendi Hu, Linbo Zhang, Xinhui Zhang, Chunyan Wei
Summary: In this study, a new hypercrosslinked polymer supported palladium catalyst was synthesized and characterized. The catalyst exhibited high efficiency in the preparation of biphenyl compounds with low catalyst loading. It also showed advantages in terms of availability of raw materials, stability, and cost-effectiveness.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Mojgan Zendehdel, Soheila Khaghaninejad, Arezoo Kheiri
Summary: In this study, an acid catalyst was synthesized by functionalizing 1-Butyl-3-methyl imidazolium azide on zeolite, resulting in a catalyst with micro-meso structure, high surface area, and good acidity. The catalyst was used for the synthesis of pyrrole derivatives under solvent-free conditions, showing high yield.
Article
Chemistry, Multidisciplinary
Kioumars Aghapoor, Farshid Mohsenzadeh, Hossein Reza Darabi, Hani Sayahi
Summary: This study demonstrated the exceptional catalytic activity of crystalline salicylic acid as an organocatalyst in solvent-free Paal-Knorr pyrrole synthesis under microwave activation. It showed high efficiency even under low microwave power irradiation or shorter reaction times, and enabled ultrafast pyrrole synthesis with no risk of metal contamination.
JOURNAL OF CHEMICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Rajkumar Kore, Anand D. Sawant, Robin D. Rogers
Summary: In an effort to overcome limitations in using ionic liquids (ILs) as homogeneous catalysts, a heterogeneous analog was prepared by loading [HN222][Al2Cl7] onto Fe3O4 nanoparticles. The catalyst showed excellent performance in the alkylation of benzene with benzyl chloride and could be recycled multiple times without loss of catalytic activity.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Spectroscopy
Shuliang Ye, Shiying Yang, Liwei Ni, Wenze Qiu, Qiyue Xu
Summary: This study thoroughly investigated the mechanism and kinetics of the Paal-Knorr reaction for pyrrole derivatives using in-situ FTIR spectroscopy, identifying and quantifying intermediate, reactants, and products. By establishing IR quantitative models, the influences of operating conditions on reaction processes were analyzed and a reaction kinetic model was built with calculated kinetic parameters. The in-situ FTIR monitoring combined with IR analysis methods proved to be a powerful tool for revealing the reaction mechanism and kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemistry & Molecular Biology
Roman O. Shcherbakov, Diana A. Eshmemet'eva, Anton A. Merkushev, Igor V. Trushkov, Maxim G. Uchuskin
Summary: A new approach to 3-(furan-2-yl)-1,3-di(het)arylprop-2-en-1-ones has been developed through the oxidative dearomatization and cyclization of di(het)aryl-substituted 2-ene-1,4,7-triones, showing high synthetic efficiency.
Article
Chemistry, Physical
Omar Portilla-Zuniga, Oscar M. Bautista-Aguilera, Jose J. Martinez, Hugo Rojas, Mario A. Macias, Isabel Iriepa, Adrian Perez-Redondo, Angel Sathicq, Juan-Carlos Castillo, Gustavo P. Romanelli
Summary: The Paal-Knorr reaction of acetonylacetone with primary amines catalyzed by CATAPAL 200 under conventional heating at 60 degrees C for 45 min resulted in N-substituted pyrroles in yields of 68-97%. CATAPAL 200, with its high percentage of Bronsted-Lewis acid sites (23%) and pore diameter (37.8 nm), promotes the formation of pyrrole ring by facilitating condensation and dehydration processes. This protocol offers simplicity, high yields, reduced reaction time, solvent-free conditions, stoichiometric amounts of reactants, low catalyst loading, and clean reaction profile. Furthermore, CATAPAL 200 is inexpensive and readily available, making it a cost-effective option for chemical transformations. The catalyst can be reused for up to five cycles without significant loss of catalytic activity, making this protocol sustainable and advantageous compared to conventional methods.
Article
Chemistry, Organic
Naresh Vempala, Anireddy Jaya Shree, Srikanth Reddy Narra, Somnath Dasgupta
Summary: A concise and efficient synthesis method for the production of atorvastatin calcium, a key cholesterol-lowering drug, has been presented.
Article
Chemistry, Physical
Hu Zhang, Zhaoyu Zhang, Zhengguo Cai, Mingyuan Li, Zhen Liu
Summary: The development of heterogeneous late transition metal catalysts for olefin (co)polymerization has been investigated. The preparation of heterogeneous anilinonaphthoquinone nickel and palladium catalysts has been reported. The nickel catalyst showed high activity for ethylene polymerization, producing high-molecular-weight polyethylenes with well-regulated morphologies. The palladium catalyst promoted copolymerization of ethylene with commercial methyl acrylate or norbornene derivatives, leading to functionalized polyethylene and cyclic olefin copolymers.
Article
Chemistry, Physical
Hu Zhang, Zhaoyu Zhang, Zhengguo Cai, Mingyuan Li, Zhen Liu
Summary: The development of heterogeneous late transition metal-catalyzed olefin (co)polymerization is challenging. This study reports the preparation of heterogeneous anilinonaphthoquinone nickel and palladium catalysts. The nickel catalyst exhibits very high activity and can produce high-molecular-weight semicrystalline polyethylenes. The polymerization behavior is influenced by the electron density of the metal center and the Lewis acidity of the alkylaluminum. The palladium catalyst promotes copolymerization of ethylene with methyl acrylate or polar norbornene derivatives.
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)