Review
Biochemistry & Molecular Biology
Joao M. Anghinoni, Paloma T. Birmann, Marcia J. da Rocha, Caroline S. Gomes, Michael J. Davies, Cesar A. Bruening, Lucielli Savegnago, Eder J. Lenardao
Summary: In this review, the synthesis and bioassays of organic selenium compounds with antioxidant activity in the past five years are discussed, presenting the most active compounds in each series.
Review
Biochemistry & Molecular Biology
Ritu Mamgain, Marina Kostic, Fateh V. V. Singh
Summary: The chemistry of organoselenium reagents plays a crucial role in organic synthesis due to their versatility as electrophiles and nucleophiles. Recent research has focused on the synthesis and antioxidant properties of these compounds, with diselenide compounds showing better antioxidant activity than selenides. The review also includes the synthesis and antioxidant activity of Selenium-based nanoparticles.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Flavio A. R. Barbosa, Romulo F. S. Canto, Kerolain F. Teixeira, Anacleto S. de Souza, Aldo S. de Oliveira, Antonio L. Braga
Summary: Alzheimer's disease (AD) is a prevalent type of dementia that affects millions of older people worldwide. Selenium-containing compounds have shown potential as multi-targeted drugs for the treatment of AD due to their antioxidant and anticholinesterase properties. These compounds can decrease the aggregation of amyloid-beta (A beta), a key feature of AD. Some selenium-derived compounds have molecular features similar to FDA-approved drugs, suggesting that they may have optimized pharmacokinetic properties.
CURRENT MEDICINAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Paloma Begines, Sergio Martos, Irene Lagunes, Ines Maya, Jose M. Padron, Oscar Lopez, Jose G. Fernandez-Bolanos
Summary: The study focuses on the preparation of novel hybrids combining organoselenium and polyphenolic compounds to obtain new antioxidants and antiproliferative agents. The compounds showed excellent antioxidant properties and potent antiproliferative activity against lung cancer cell lines. These findings suggest their potential as new drug candidates.
Article
Chemistry, Physical
Irfan Sahin, Fatma Betul Ozgeris, Muhammet Kose, Ebubekir Bakan, Ferhan Tumer
Summary: This study synthesized six 1,2,3-triazole derivatives and investigated their antioxidant and anticancer activities. The results showed that some of the compounds exhibited significant anticancer activity.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Inorganic & Nuclear
Laurenzo D. V. Alba, Tsubasa Hatanaka, Francisco C. Franco, Masaki Nojiri, Marissa G. Noel, Yasuhiro Funahashi
Summary: The crystal structure of a new silver complex of O-acetylsinigrin demonstrates chelating bonds of sulfated thiohydroximate and an η(2)-bond of the ethylene moiety with Ag(I). Mechanistic studies through H-1 NMR measurements and theoretical calculations suggest relevance to glucosinolate degradation in biological systems.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Physical
Nefise Ozcelik, Tuncay Tunc, Raziye Catak Celik, Mahmut Erzengin, Haci Ozisik
Summary: A newly synthesized hydrazone derivative was characterized using various methods including XRD for crystal structure determination and antioxidant activity testing. The results showed potential radical scavenging ability of the synthesized compound.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Biochemistry & Molecular Biology
Kundan Tayade, Gyu-Seong Yeom, Suban K. Sahoo, Horst Puschmann, Satish Balasaheb Nimse, Anil Kuwar
Summary: This study synthesized Schiff base compound 2 and determined its crystal structure and molecular structure. The antioxidant activity of this compound was confirmed through calculations and experiments. The compound exhibited excellent antioxidant activity and low cytotoxicity.
Article
Chemistry, Inorganic & Nuclear
Shreya Mahato, Nishith Meheta, Muddukrishnaiah Kotakonda, Mayank Joshi, Madhusudan Shit, Angshuman Roy Choudhury, Bhaskar Biswas
Summary: This study focuses on the synthesis, structure, oxidation performance, and antibacterial activity of a zinc-Schiff base complex, showing promising results in catalyzing the oxidation of 4-methylcatechol and destroying bacterial cell membranes. The complex has the potential to be developed into a future antibacterial agent.
Article
Chemistry, Inorganic & Nuclear
Satyendra Kumar, Malathy Selvachandran, Kuppuswamy Arumugam, Mohamed C. Shaw, Che Wu, Michael Maurer, Xiaodong Zhang, Stephen Sproules, Joel T. Mague, James P. Donahue
Summary: Open-ended, singly metalated dithiolene complexes were prepared using different methods, and their structures were characterized by X-ray crystallography.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Malte Sachs, Sergei I. Ivlev, Martin Etter, Matthias Conrad, Antti J. Karttunen, Florian Kraus
Summary: UIr, previously considered as a noncentrosymmetric material, is discovered to have a centrosymmetric crystal structure. The observation of twinning suggests a high-temperature displacive phase transition in UIr. The study impacts the understanding of the structure models and superconducting mechanisms of UIr.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Summaira Fayyaz, Farzana Shaheen, Saqib Ali, Samar Naseer, Scopelliti Rosario
Summary: The synthesis of five new antimicrobial organotin(IV) carbodithioates with different coordination geometries in solid and solution states showed significant activity against five different bacterial strains.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Physics, Multidisciplinary
Qian Zhao, Ying-Hao Zhu, Si Wu, Jun-Chao Xia, Peng-Fei Zhou, Kai-Tong Sun, Hai-Feng Li
Summary: A YCrO3 single crystal with an orthorhombic structure and antiferromagnetic behavior was successfully grown using the floating-zone method. The simultaneous occurrence of antiferromagnetism and weak ferromagnetism was observed, along with strong local lattice distortions.
Article
Chemistry, Physical
Karthik Rajagopal, Saravanan Dhandayutham, Manivannan Nandhagopal, Mathivanan Narayanasamy
Summary: This research work successfully synthesized bis-benzimidazole derivatives using simple and eco-friendly reaction conditions and crystallization procedures. The structures of the compounds were determined using 1H NMR, 13C NMR, and mass spectroscopic techniques. Among these derivatives, compound 1c exhibited crystal nature as confirmed by single crystal X-ray study. The synthesized compounds were tested for antimicrobial activity against various human bacterial and fungal pathogens, and compound 1e demonstrated the best inhibitory effect with a minimum inhibitory concentration of 16 μg/mL against C. albicans. Molecular docking analysis further revealed that compound 1g had the best binding energy with fungal protein C. albicans.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Crystallography
Wanyue Peng, Sviatoslav Baranets, Svilen Bobev
Summary: Crystals of a new ternary compound, Ca3InAs3, have been successfully synthesized in the Ca-In-As family. The compound crystallizes in the orthorhombic space group and has InAs4 tetrahedra as the smallest building motifs. Electronic structure calculations confirm the opening of a bandgap and show intermediate covalent/ionic interactions between Ca and As, as well as strong covalent features of the In-As interactions.
Article
Chemistry, Multidisciplinary
Santosh L. Gawali, Kanhu C. Barick, Neena G. Shetake, Vasumathy Rajan, Badri N. Pandey, N. Naveen Kumar, K. Indira Priyadarsini, Puthusserickal A. Hassan
Article
Pharmacology & Pharmacy
Gunjan Verma, Neena G. Shetake, Shruti Pandrekar, B. N. Pandey, P. A. Hassan, K. Priyadarsini
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Biochemistry & Molecular Biology
K. A. Gandhi, J. S. Goda, V. V. Gandhi, A. Sadanpurwala, V. K. Jain, K. Joshi, S. Epari, S. Rane, B. Mohanty, P. Chaudhari, S. Kembhavi, A. Kunwar, V. Gota, K. I. Priyadarsini
FREE RADICAL BIOLOGY AND MEDICINE
(2019)
Article
Materials Science, Biomaterials
Bijaideep Dutta, Anshika Nema, Neena G. Shetake, Jagriti Gupta, K. C. Barick, Malini A. Lawande, B. N. Pandey, Indira K. Priyadarsini, P. A. Hassan
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2020)
Review
Biochemistry & Molecular Biology
A. Kunwar, K. Indira Priyadarsini, Vimal K. Jain
Summary: This comprehensive review highlights the potential of the organoselenium compound DSePA for various biological applications, including antioxidative, anticarcinogenic, and radioprotective activities. Studies have shown that DSePA exhibits protective effects against radiation-induced normal tissue side effects, particularly in lung tissue, and has promising pharmacokinetic properties with maximum absorption in the lung.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
(2021)
Article
Chemistry, Multidisciplinary
Kanhu C. Barick, Bijaideep Dutta, Santosh L. Gawali, Prasad P. Phadnis, Kavirayani Indira Priyadarsini, Vimal K. Jain, Puthusserickal A. Hassan
Article
Materials Science, Biomaterials
Sandeep B. Shelar, Santosh L. Gawali, Kanhu C. Barick, Amit Kunwar, Arivozhi Mohan, Indira K. Priyadarsini, Puthusserickal A. Hassan
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2020)
Article
Biochemistry & Molecular Biology
Bharti Patel, Subrata Mishra, Indira K. Priyadarsini, Sirisha L. Vavilala
Summary: The study demonstrates that selenocystine has potential anti-biofilm properties against bacteria causing respiratory tract infections, inhibiting growth and reducing biofilm formation. Selenocystine effectively eradicates preformed biofilms and distorts biofilm structures by degrading eDNA components.
BIOLOGICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
V. V. Gandhi, K. A. Gandhi, L. B. Kumbhare, J. S. Goda, V Gota, K. Priyadarsini, A. Kunwar
Summary: DSePA induces apoptosis in human lung cancer cells by reducing ROS and increasing reducing equivalents, activating intrinsic and extrinsic pathways, and inducing ER stress.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Gunjan Verma, Akhil Gajipara, Sandeep B. Shelar, K. Priyadarsini, P. A. Hassan
Summary: The CUR-Gel-HAp formulation displayed enhanced cytotoxicity against human lung cancer cells, showed long-term stability, and maintained physicochemical properties and colloidal stability after reconstitution in aqueous medium.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Shaukat Ali Shaikh, Bharti Patel, Indira K. Priyadarsini, Sirisha L. Vavilala
Summary: This study discovers that ebselen has potent antibacterial and antibiofilm activity against Serratia marcescens, and it also shows promising anti-quorum sensing potential. This suggests that ebselen could be explored as a treatment for bacterial infections.
INTERNATIONAL MICROBIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Shaukat Ali M. Shaikh, S. L. Gawali, V. K. Jain, K. Priyadarsini
Summary: The interaction between diselenodipropionic acid (DSePA) and human serum albumin (HSA) has been investigated using spectroscopic and docking methods. The binding constant between DSePA and HSA was estimated, and the molecular interaction was confirmed using isothermal titration calorimetry. The HSA-DSePA complex was analyzed using small angle X-ray scattering and circular dichroism techniques. Molecular docking studies suggested specific interactions at certain amino acid residues. These findings provide evidence for the interaction between DSePA and HSA.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
A. Kunwar, K. Indira Priyadarsini
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
(2020)
Article
Biochemistry & Molecular Biology
K. Priyadarsini, V. V. Gandhi, A. Kunwar
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
(2020)
Article
Chemistry, Multidisciplinary
Beena G. Singh, Pavitra Kumar, P. Phadnis, Michio Iwaoka, K. Indira Priyadarsini
NEW JOURNAL OF CHEMISTRY
(2019)
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)