Article
Chemistry, Multidisciplinary
Teng Yuan, Qi Tang, Chuan Shan, Xiaohan Ye, Jin Wang, Pengyi Zhao, Lukasz Wojtas, Nicholas Hadler, Hao Chen, Xiaodong Shi
Summary: This study presents a novel method for alkyne trifunctionalization through gold catalysis, achieving consecutive reactions with high efficiency and excellent yields under mild conditions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Physical
Jiang-Lin Hu, Felix Bauer, Bernhard Breit
Summary: A novel ruthenium-catalyzed synthetic method for branched allylic esters via addition of carboxylic acids to allenes was reported in this study. Ligands based on the Josiphos skeleton were designed and prepared, achieving high yield and high enantiomeric excess. Deuterium labeling experiment was conducted to propose a plausible mechanism, and enantiopure lactones of five- and six-membered ring were synthesized through a RCM reaction of the branched allylic ester product.
Article
Chemistry, Applied
Avedis Karadeolian, Michael Emmett, Fabio Souza, Andrew Chung, Peter Blazecka, Richard Le Sueur, Dineshkumar Patel, Yajun Zhao, Allan Rey, Stuart Green
Summary: The stereoselective synthesis of zuclomiphene was achieved using a nickel catalyst, resulting in high purity through the development of alternative routes to overcome impurities.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2022)
Article
Chemistry, Multidisciplinary
Anh Vy Tran, Seok-Kyu Park, Hye Jin Lee, Tae Yong Kim, Younhwa Kim, Young-Woong Suh, Kwan-Young Lee, Yong Jin Kim, Jayeon Baek
Summary: Efficient ring-opening coupled with hydrogenation of 2,5-furan dicarboxylic acid to produce adipic acid was achieved using a recyclable Ru/Al2O3 catalyst and an ionic liquid, [MIM(CH2)(4)SO3H]I, which delivered 99% overall yield. The Ru/Al2O3 catalyst showed high efficiency for the conversion of FDCA, and the ionic liquid system exhibited superior activity and reduced corrosion problems compared to conventional catalytic systems.
Article
Chemistry, Multidisciplinary
Anh Vy Tran, Seok-Kyu Park, Hye Jin Lee, Tae Yong Kim, Younhwa Kim, Young-Woong Suh, Kwan-Young Lee, Yong Jin Kim, Jayeon Baek
Summary: The production of adipic acid from 2,5-furandicarboxylic acid via tetrahydrofuran-2,5-dicarboxylic acid using a recyclable Ru/Al2O3 catalyst in ionic liquid solvent is demonstrated in this research article.
Article
Chemistry, Organic
Long-Tao Huang, Yuki Hirata, Yoshimi Kato, Luqing Lin, Masahiro Kojima, Tatsuhiko Yoshino, Shigeki Matsunaga
Summary: The study presents ruthenium(II)-catalyzed enantioselective C-H functionalization reactions of sulfoximines with sulfoxonium ylides. The combination of [RuCl2(p-cymene)](2) and a pseudo-C-2-symmetric binaphthyl monocarboxylic acid yielded S-chiral products in 76:24 to 92:8 er.
SYNTHESIS-STUTTGART
(2022)
Article
Chemistry, Organic
Uttam Dhawa, Robert Connon, Joao C. A. Oliveira, Ralf Steinbock, Lutz Ackermann
Summary: The asymmetric ruthenium-catalyzed C-H alkylations were achieved using a chiral C2-symmetric carboxylic acid, resulting in chiral tetrahydrocarbazoles and cyclohepta[b]indoles with high enantioselectivity at room temperature. Mechanistic studies revealed a fast C-H ruthenation process, with a rate- and enantio-determining proto-demetalation step. The asymmetric induction was governed by weak attractive secondary dispersion interactions, as shown in NCI analysis of the key transition states.
Review
Chemistry, Physical
Leila Karam, Constanze N. Neumann
Summary: This critical review focuses on the synthesis of alcohols through the hydrogenation of carboxylic acids using heterogeneous metal catalysts. It discusses the reactivity of carboxylic acid derivatives, different mechanisms for carboxylic acid hydrogenation, undesired side product formation, and the reactivity of different types of carboxylic acid substrates. The review also provides guidance on selecting appropriate reaction conditions.
Article
Chemistry, Multidisciplinary
Mengsheng Li, Jing Zhang
Summary: Efficient strategies for accessing nitriles from common organic functionalities are of great importance in synthetic and medicinal chemistry. This study presents an iron-catalyzed deoxynitrogenation strategy to convert carboxylic acids into nitriles. The method utilizes a cyanamide as the recyclable nitrogen donor and deoxygenating reagent, and can be applied to aryl, alkenyl, and alkyl carboxylic acids without the need for inert gas protection. The practicality of this method is demonstrated through its application in late-stage modification of drug molecules, synthesis of a pharmaceutical structure, and scaleup reactions and downstream derivatizations.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Physical
Ziqiao Zhou, Hongchao Liu, Zhiyang Chen, Wenliang Zhu, Zhongmin Liu
Summary: Decarbonylation of carboxylic acids using heterogeneous zeolite catalyst can efficiently produce methyl acetate from acetic acid, ethylene from propionic acid, and propylene from butanoic acid, with selectivities around 70%-90%. This approach provides new insights into alkene production from biomass.
Article
Chemistry, Applied
Yuguang Wang, Hengliang Liu, Donglin Cai, Jinqiu Zhou, Mengjing Wu, Huifang Zheng, Deming Xie
Summary: A high-performance and recyclable high valence oxides of ruthenium catalyst was successfully released from commercially available ruthenium carbon catalyst. It selectively oxidized C=C bonds and C equivalent to C bonds to yield corresponding aldehydes, ketones, and alpha-diketones with high yields. The catalyst, with its cheap availability, recyclability, safety, and low toxicity, shows great potential in industrial scale unsaturated bond oxidation cleavage applications.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Hongyu Guo, Sheng Zhang, Yang Li, Xiaoqiang Yu, Xiujuan Feng, Yoshinori Yamamoto, Ming Bao
Summary: A palladium-catalyzed tail-to-tail reductive dimerization reaction of terminal alkynes is reported for the first time, leading to the efficient transformation of aromatic and aliphatic alkynes into 2,3-dibranched butadienes. The control of reaction solution acidity, achieved by a combination of pivalic acid and para-toluenesulfonic acid, is crucial for the selective tail-to-tail reductive dimerization reaction, which is proposed to proceed via a cationic alkenyl palladium intermediate under acidic conditions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Organic
Xingxing Zhang, Guangyuan Liu, Yiyuan Peng, Hua Li, Yirong Zhou
Summary: A rhodium-catalyzed cross-coupling/annulation reaction was developed for the synthesis of diverse trifluoromethylated indolopyranones. This reaction combines three valid pharmacophores (indole, pyranone, and trifluoromethyl) into one molecule, making it a useful precursor for drug synthesis. The reaction showed excellent regioselectivity and high functional group tolerance, making it a versatile method for the synthesis of complex molecules.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Yoshimi Kato, Luqing Lin, Masahiro Kojima, Tatsuhiko Yoshino, Shigeki Matsunaga
Summary: By introducing pseudo-C2 symmetric tunable chiral carboxylic acids, the study achieved enantioselective C(sp(3))-H amidation reactions of substrates such as 2-alkylpyridines, improving the chiral selectivity towards the substrates.
Article
Chemistry, Organic
Thomas H. Hall, Hannah Adams, Vijyesh K. Vyas, K. L. Michael Chu, Martin Wills
Summary: A detailed study was conducted on the asymmetric transfer hydrogenation (ATH) of a series of enones using Ru(II) catalysts. The ATH reaction can readily discriminate between double and triple bonds adjacent to ketones, reducing the double bond but leaving a triple bond intact in the major product.
Article
Chemistry, Inorganic & Nuclear
Chandan Kumar Karan, Manish Bhattacharjee
INORGANIC CHEMISTRY
(2018)
Article
Chemistry, Physical
Uttam Kumar Das, Yehoshoa Ben-David, Gregory Leitus, Yael Diskin-Posner, David Milstein
Article
Chemistry, Inorganic & Nuclear
Chandane Kumar Karan, Manish Bhattacharjee
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Uttam Kumar Das, Amit Kumar, Yehoshoa Ben-David, Mark A. Iron, David Milstein
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Article
Chemistry, Multidisciplinary
Chandan Kumar Karan, Sourav Mallick, C. Retna Raj, Manish Bhattacharjee
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Correction
Chemistry, Inorganic & Nuclear
Chandan Kumar Karan, Manish Bhattacharjee
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2020)
Article
Chemistry, Applied
Uttam Kumar Das, Sayan Kar, Yehoshoa Ben-David, Yael Diskin-Posner, David Milstein
Summary: The first example of homogeneously catalyzed hydrogenation of the N=N bond of azo compounds has been reported using a complex of an earth-abundant-metal. The hydrogenation reaction is catalyzed by a manganese pincer complex, proceeds under mild conditions, and yields amines, which makes this methodology a sustainable alternative route for the conversion of azo compounds. A plausible mechanism involving metal-ligand cooperation and hydrazine intermediacy is proposed based on mechanistic studies.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Multidisciplinary
Yaoyu Liang, Uttam Kumar Das, Jie Luo, Yael Diskin-Posner, Liat Avram, David Milstein
Summary: This article presents a catalyst based on magnesium complexes and explores its potential in environmentally friendly organic transformations through metal-ligand cooperation for hydrogen activation. The catalyst showed remarkable performance in semihydrogenation of alkynes and hydrogenation of alkenes, providing high yields and selectivities.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Mita Dutta, Chandan Kumar Karan, Manish Bhattacharjee
Summary: In this study, three metal-organic hydrogels were prepared using a low molecular weight gelator. The gels exhibited multi-responsive behavior and showed self-healing properties. They also demonstrated selective adsorption and degradation of dyes.
Article
Chemistry, Inorganic & Nuclear
Ramaraj Ayyappan, Uttam Kumar Das, Issam Abdalghani, Rosenildo C. Da Costa, Graham J. Tizzard, Simon J. Coles, Gareth R. Owen
Summary: The reaction between 6-DiPPon and [RuCl2(p-cymene)]2 resulted in the formation of two complexes with different ligands, the ratio of which can be controlled by the solvent used. In the presence of AgOTf and Na[BArF24], two other complexes were formed. The properties and reaction mechanisms of these new ligands and complexes have important implications for catalyst activity and applications.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Mita Dutta, Shreya Banerjee, Mahitosh Mandal, Manish Bhattacharjee
Summary: A self-healable metallohydrogel of Mn(ii) has been successfully prepared using a low molecular weight gelator, Na2HL. It has been characterized by various techniques and encapsulated with drugs IND and GEM. The GEM-loaded metallogel showed enhanced delivery and cytotoxicity against breast cancer cells, while the MOG_IND exhibited improved anti-inflammatory response compared to the drug alone.
Article
Chemistry, Multidisciplinary
Rajesh K. Jena, Mahesh Samanta, Mohan C. Sau, Sonali Panda, Braja N. Patra, Manish Bhattacharjee
Summary: A complex ruthenium compound has been synthesized and characterized, which exhibits high efficiency as a catalyst in carbon-carbon bond formation reactions. The use of specific additives can increase selectivity and prevent the generation of unwanted side products.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Mohan Chandra Sau, Smita Mandal, Manish Bhattacharjee
Summary: Monoallylation and monoalkylation of diketones and beta-keto esters with allylic and benzylic alcohols catalyzed by [Cp*Co(CH3CN)(3)][SbF6](2) have been reported, yielding regioselective products for the synthesis of trisubstituted pyrazoles and one pyrazolone. Mechanistic investigations revealed reactions proceed via eta(3)-allyl complex formation or ally ether intermediate for allylation, while alkylation takes place solely via ether intermediate.
Article
Chemistry, Multidisciplinary
Mohan Chandra Sau, Manish Bhattacharjee
Article
Chemistry, Multidisciplinary
Uttam Kumar Das, Trevor Janes, Amit Kumar, David Milstein
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
