Article
Chemistry, Multidisciplinary
Yong Wang, Yanwen Xu, Jingying Yang, Xiaoyan Qiu, Nan Li, Yuejin Zhu, Lijuan Yan, Weiping Li, Xianjian Huang, Kaiyuan Liang, Rongjun Guo, Hui Tan, Haizhou Yu
Summary: The newly synthesized DOX/CB@DMSNs(R) nanoparticles exhibit excellent boron loading capacity and sufficient therapeutic dosage delivery, suppressing boron leakage into the bloodstream and selectively delivering to the tumor site. Designed carefully, these nanoparticles may serve as a BNCT agent and a carrier of chemotherapy drugs, precisely targeting tumor cells and delivering sufficient drug dosage safely.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Xinbin Gong, Xiao Feng, Jieqi Cao, Yinwei Wang, Xiaoxia Zheng, Weiqiang Yu, Xinhong Wang, Song Shi
Summary: This study introduces an efficient strategy for promoting the synthesis of gamma-valerolactone (GVL) via levulinic acid (LA) hydrogenation by controlling the surface wettability. The hydrophobic catalysts showed higher activity than the hydrophilic ones in the reaction, which is important for bio-based molecule upgrading.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Cameron W. Evans, Diwei Ho, Joshua B. Marlow, Jessica J. King, Charmaine Hee, Lucas N. Wong, Rob Atkin, Nicole M. Smith, Gregory G. Warr, Marck Norret, K. Swaminathan Iyer
Summary: Non-viral delivery is an important strategy for gene therapy, immunization, and RNA interference, but the efficiency of current non-viral carriers is limited. Researchers have developed dendronized bottlebrush polymers with controlled defects, showing that synthetic macromolecular complexes can communicate intracellularly. This challenges the assumption that delivery agents act as bystanders and improves the design of non-viral delivery agents for genome engineering, vaccines, and nucleic acid-based therapies.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Biology
Agostina Vitali, Maria Paola Demichelis, Greta Di Martino, Ian Postuma, Silva Bortolussi, Andrea Falqui, Chiara Milanese, Chiara Ferrara, Patrizia Sommi, Umberto Anselmi-Tamburini
Summary: In this study, multifunctional boron carbide nanoparticles stabilized with polyacrylic acid (PAA) and a gadolinium (Gd)-rich solid phase were synthesized and their biological activity was evaluated. The incorporation of a fluorophore (DiI) allowed for confocal microscopy imaging of the nanoparticles. Novel correlative microscopy techniques were employed to analyze the interaction and activity of these fluorescent Gd-containing B4C nanoparticles (FGdBNPs) with cultured cells. The results indicate that these nanoparticles have the potential to achieve high boron concentration in tumor cells.
Editorial Material
Chemistry, Inorganic & Nuclear
Cyril Godard, Carmen Claver, Ana C. Albeniz
Summary: Supported catalysts offer both the activity of molecular catalysts and the convenience and reusability of catalysts in a difference phase. With continuous solutions to common problems such as leaching, supported catalysts are becoming increasingly viable for applied research.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Physics, Fluids & Plasmas
Saad Yalouz, Vincent Pouthier
Summary: This study investigates the energy absorption of photoexcitation at the core of a star network, which is distributed uniformly at the periphery. The existence of an optimal value of energy defect is revealed, which depends on the network architecture. When certain conditions are met, the absorption process can be accelerated. The findings of this study may serve as a potential guide for the design of efficient molecular nanonetworks for photoexcitation absorption.
Article
Oncology
Miquel Nuez-Martinez, Catarina I. G. Pinto, Joana F. Guerreiro, Filipa Mendes, Fernanda Marques, Amanda Munoz-Juan, Jewel Ann Maria Xavier, Anna Laromaine, Valeria Bitonto, Nicoletta Protti, Simonetta Geninatti Crich, Francesc Teixidor, Clara Vinas
Summary: The study evaluates the potential of sodium salt of cobaltabis(dicarbollide) and its di-iodinated derivative as promising agents for dual anti-cancer treatment for GBM. Results show enhanced resistance in U87 cell lines in 3D models, contrasting the observations in monolayer cultures. BNCT is more effective on T98G cells after their incubation with Na[8,8 '-I-2-o-COSAN].
Article
Chemistry, Applied
M. Arkas, M. Douloudi, E. Nikoli, G. Karountzou, I Kitsou, E. Kavetsou, D. Korres, S. Vouyiouka, A. Tsetsekou, K. Giannakopoulos, M. Papageorgiou
Summary: In this study, silver nanoparticles were synthesized using PEI as a template and immobilized on silica substrates to create hybrid nanocatalysts. The effects of different PEIs and pH regulators were investigated, and the catalytic performance was improved through organic scaffold pyrolysis. This eco-friendly synthesis procedure proved to be a successful alternative for producing multifunctional nanomaterials at ambient temperature.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Chemistry, Medicinal
Mayk C. Ramos, Patrick K. Quoika, Vitor A. C. Horta, Douglas M. Dias, Elan G. Costa, Jorge L. M. do Amaral, Luigi M. Ribeiro, Klaus R. Liedl, Bruno A. C. Horta
Summary: pyPolyBuilder is a practical tool implemented in Python for generating topologies of arbitrary supramolecules, suitable for linear polymer chains and large branched molecules, providing reasonable starting structures for simulations of these molecules. It can be easily incorporated into existing simulation pipelines on any operating system.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2021)
Article
Polymer Science
Anjara Morgado, Francisco Najera, Anna Lagunas, Josep Samitier, Yolanda Vida, Ezequiel Perez-Inestrosa
Summary: The study presents a novel synthesis method for preparing slightly sterically hindered amino terminal polyamide dendrimers. By utilizing an AB(2) scaffold and specific relative positions of amino groups, robust dendritic structures were successfully constructed and thoroughly characterized, demonstrating a substantial improvement in the preparation of stable dendrimers with high yield and simplified purification procedures.
Article
Polymer Science
Eduard Karakhanov, Anton Maximov, Anna Zolotukhina
Summary: This article reviews the recent advances and applications of dendritic catalysis in the past two decades, with a focus on heterogeneous dendrimer-based catalysts. Three main approaches to synthesizing immobilized heterogeneous dendrimer-based catalysts are considered, and magnetically separable dendritic catalysts are also discussed. These dendritic catalysts can be stored as powders and easily separated from the reaction medium, maintaining efficiency similar to homogeneous dendritic catalysts.
Article
Chemistry, Physical
Weihang Li, Hui Liu, Hao Wang, Yiwen Chen, Yan Peng, Haitao Wu, Yujia Hou, Yue Huang, Zhaoyang Yuan, Bangjiao Ye, Hongjun Zhang, Jinrong Wu
Summary: Loose connective tissue in the human body has a unique network structure that makes it tough and healable. Inspired by this structure, a class of tough and healable polymeric glasses (THGs) was developed by creating salt bridges between a hyperbranched polymer and high-molecular-weight linear copolymers. THGs exhibit high yield strength, Young's modulus, and toughness, outperforming most commercial glassy polymers. Furthermore, THGs can be easily healed below and around the glass-transition temperature. This biomimetic approach enables the development of glassy polymers with a combination of high strength, excellent toughness, and self-healing ability.
CHEMISTRY OF MATERIALS
(2023)
Article
Polymer Science
Shuang Fu, Niu Niu, Shanliang Song, Dingyuan Yan, Jinyin Ge, Jiangao Li, Zhengli Peng, Lianwei Li, Yu Xiong, Lei Wang, Dong Wang, Ben Zhong Tang
Summary: In this study, dendritic amphiphiles with aggregation-induced emission characteristics were successfully constructed using tetraphenylethene derivatives as the bridge fragment. The self-assembly of these dendritic amphiphiles into different morphological structures, such as tubules and nanofibers, was controlled by the solvent effect. Furthermore, these supramolecular materials exhibited excellent performance as fluorescent photosensitizers for fluorescence image-guided photodynamic cancer therapy.
Article
Polymer Science
Tathagata Mondal, Maria Nerantzaki, Kevin Flesch, Capucine Loth, Mounir Maaloum, Yidan Cong, Sergei S. Sheiko, Jean-Francois Lutz
Summary: The DNA-guided assembly of biohybrid sequence-defined poly(phosphodiester)s was investigated, resulting in the synthesis of linear or star-like superstructures. Characterization through electrophoresis, UV spectroscopy, and atomic force microscopy confirmed the formation of the expected supramolecules, despite some defects. This approach offers interesting avenues for designing 2D and 3D constructs based on informational poly(phosphodiester)s.
Review
Engineering, Biomedical
Zimeng Zhai, Yiyun Cheng, Jiaxu Hong
Summary: Glaucoma, the leading cause of irreversible blindness worldwide, requires long-term management with drugs, but there is a shortage of effective antiglaucoma drugs due to biological barriers of the human eyes. Nanomedicines have emerged as promising alternatives to conventional ophthalmic formulations, offering improved drug delivery and potential for neuroprotective treatment of damaged nerves in glaucoma.
ACTA BIOMATERIALIA
(2021)
Article
Chemistry, Analytical
Jing-yan Kang, Yu-jie Zhang, Xing Li, Chen Dong, Hong-yu Liu, Li-jing Miao, Paul J. Low, Zhi-xian Gao, Narayan S. Hosmane, Ai-guo Wu
ANALYTICAL METHODS
(2018)
Article
Chemistry, Multidisciplinary
Xinmei Zhao, Leyong Zeng, Narayan Hosmane, Yan Gong, Aiguo Wu
CHINESE CHEMICAL LETTERS
(2019)
Review
Chemistry, Inorganic & Nuclear
Yinghuai Zhu, Shanmin Gao, Narayan S. Hosmane
INORGANICA CHIMICA ACTA
(2018)
Article
Chemistry, Inorganic & Nuclear
Yinghuai Zhu, Zhiyu Bai, Wen Chuen Phuan, Fatima Abi Ghaida, Narayan S. Hosmane, Jun Ding
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2018)
Article
Materials Science, Biomaterials
Okan Icten, Dursun Ali Kose, Stephan J. Matissek, Jason A. Misurelli, Sherine F. Elsawa, Narayan S. Hosmane, Birgul Zumreoglu-Karan
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Yinghuai Zhu, Narayan S. Hosmane
PURE AND APPLIED CHEMISTRY
(2018)
Article
Biochemistry & Molecular Biology
Yinghuai Zhu, Yongxiang Lin, Narayan S. Hosmane
BIOORGANIC CHEMISTRY
(2019)
Article
Chemistry, Medicinal
Marlon R. Lutz, Sebastian Flieger, Andre Colorina, John Wozny, Narayan S. Hosmane, Daniel P. Becker
Article
Chemistry, Multidisciplinary
Yinghuai Zhu, Parichat Prommana, Narayan S. Hosmane, Paolo Coghi, Chairat Uthaipibull, Yingjun Zhang
Summary: Boron nanoparticles with hydroxyl groups were synthesized in situ and characterized using various analytical techniques. These nanoparticles exhibited good antimalarial activity against Plasmodium falciparum, while showing low toxicity to various cell lines.
Review
Biochemistry & Molecular Biology
Bhaskar C. Das, Nitesh K. Nandwana, Sasmita Das, Varsha Nandwana, Mohammed Adil Shareef, Yogarupa Das, Mariko Saito, Louis M. Weiss, Frankis Almaguel, Narayan S. Hosmane, Todd Evans
Summary: This review introduces current boron-containing drug candidates, including boron-based compounds for the treatment of different diseases. It also describes their synthesis, structure-activity relationship, and associated biological activities.
Article
Biochemistry & Molecular Biology
Martha L. Jimenez-Gonzalez, Juan Pablo F. Rebolledo-Chavez, Marisela Cruz-Ramirez, Rene Antano, Angel Mendoza, Narayan S. Hosmane, Lena Ruiz-Azuara, Jose Luis Hernandez-Lopez, Luis Ortiz-Frade
Summary: In this work, an electrochemical study of the Boron cage monomercaptoundecahydro-closo-dodecaborate [B12H11SH](2-) in solution and in a self-assembled monolayer over a gold electrode was conducted. The study revealed the interaction between the boron cage and the gold surface, formation of a self-assembled monolayer, and the reduction of active sites on the gold surface due to the presence of the boron cage. Bulkier thiols were found to enhance charge accumulation at the electrode-solution interface.
Review
Biochemistry & Molecular Biology
Varsha Nandwana, Nitesh K. Nandwana, Yogarupa Das, Mariko Saito, Tanisha Panda, Sasmita Das, Frankis Almaguel, Narayan S. Hosmane, Bhaskar C. Das
Summary: This review article summarizes the importance of gut microbiota in neurodevelopment and neurodegenerative disorders and discusses breakthroughs in using probiotics, prebiotics, and synbiotics for treating neurological illnesses. It also explores the role of a boron-based diet in memory and neurodegenerative diseases.
Article
Biochemistry & Molecular Biology
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R. Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham Moran, Prakasha Kempaiah, Narayan Hosmane, Minoru Suzuki, Daniel P. Becker
Summary: New carborane-bearing hydroxamate matrix metalloproteinase (MMP) ligands with nanomolar potency against MMP-2, -9 and -13 have been synthesized for boron neutron capture therapy (BNCT). In vitro studies showed that these new MMP ligands had high tumoricidal effects in the BNCT assay. This study highlights the importance of targeting MMP enzymes overexpressed on the surface of tumor cells for BNCT efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Yinghuai Zhu, Jianghong Cai, Narayan S. Hosmane, Minoru Suzuki, Kazuko Uno, Yingjun Zhang, Mao Takagaki
Summary: Carboxyboranylamino ethanol was prepared with a 75.0% yield through an amine-exchange reaction. It showed lower cytotoxicity and higher anti-tumor efficacy in vitro compared to 4-borono-l-phenylalanine (BPA) and methyl 2-hydroxyl-5-(1'-ortho-carbonylmethyl-1',2',3'-triazol-4'-yl)-benzonate (2). The bio-enhancement was explained using molecular docking calculations.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Hongyu Liu, Zhuangwei Zhou, Yujie Zhang, Ningyi Chen, Jingyan Kang, Guijian Liu, Narayan S. Hosmane, Aiguo Wu
NANOSCALE ADVANCES
(2019)
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
