期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 79, 期 9, 页码 3924-3929出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo5003856
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资金
- National Natural Science Foundation of China [21232003, 21202053, 21272087]
- National Basic Research Program of China [2011CB808603]
- China Scholarship Concil
An asymmetric synthesis of epoxyoxindoles from isatins has been developed by employing chiral sulfur ylides generated in situ from camphor-derived sulfonium salts. This reaction allows an efficient access to enantioenriched spiro-epoxyoxindoles under mild reaction conditions, featuring high yields and excellent enantio- and diastereoselectivities.
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