期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 77, 期 5, 页码 2331-2336出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo2026433
关键词
-
资金
- National Natural Science Foundation of China [20972085, 21032004]
- National Basic Research Program of China [2012CB933402]
An efficient strategy for the synthesis of a variety of 3-substituted isocoumarins has been developed. The reaction proceeded from o-halobenzoic acids and 1,3-diketones via a copper(I)-catalyzed domino reaction in DMF under the action of K3PO4 at 90-120 degrees C without a ligand to afford the corresponding 3-substituted isocoumarin derivatives in good to excellent yields. o-Halobenzoic acids could be o-iodobenzoic acid, o-bromobenzoic acid, and o-chlorobenzoic acid derivatives. 1,3-Diketones could be alkyl- and aryl-substituted 1,3-diketones.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据