期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 76, 期 11, 页码 4617-4627出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo200517w
关键词
-
资金
- Syngenta
Treatment of a range of 2,3- and 3,4-epoxy amines with HBF4 center dot OEt2 at room temperature results in fast and efficient S(N)2-type ring-opening hydrofluorination to give stereodefined amino fluorohydrins. Operational simplicity, scalability, and short reaction time at ambient temperature are notable features of this method, The utility of this methodology is exemplified in a concise asymmetric synthesis of (S,S)-3-deoxy-3-fluorosafingol.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据