Article
Chemistry, Multidisciplinary
Hong Huang, Xiang-Guang Meng, Wen-Wang Yu, Li-Yu Chen, Yan-Yan Wu
Summary: The study prepared a polyacrylonitrile catalyst for the isomerization of glucose to fructose, maintaining high yield and selectivity over a wide range of pH values.
Article
Chemistry, Organic
Ting Chen, Jin-Tian Ma, Xiang-Long Chen, You Zhou, Zhi-Cheng Yu, Shuang-Gui Lei, Yan-Dong Wu, Jia-Chen Xiang, An-Xin Wu
Summary: We report a highly efficient one-pot, four-component reaction mediated by I-2-DMSO to construct a multifunctional fused system. This approach allows for selective formation of aromatics and non-aromatics under temperature control, resulting in planar and non-planar tetracyclic architectures that can be converted using simple methods.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Tynchtyk Amatov, Nobuya Tsuji, Rajat Maji, Lucas Schreyer, Hui Zhou, Markus Leutzsch, Benjamin List
Summary: This study reports two highly enantioselective and diastereoselective catalytic Mukaiyama aldol reactions, which directly deliver valuable silyl protected propionaldehyde aldols with control over stereochemistry. A single atom modification in the catalyst core leads to a dramatic switch in enantioselectivity of the aldehyde through unconventional C-H hydrogen bonding interactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Elise B. Gilcher, Hochan Chang, George W. Huber, James A. Dumesic
Summary: The hydrogenation of a biomass-derived platform molecule, 5-hydroxymethyl furfural (HMF)-acetone-HMF (HAH), was studied over Pd, Ru, and Cu based catalysts at temperatures ranging from 313-393 K. Different catalysts exhibited varying levels of selectivity and reaction pathways for hydrogenation. Kinetic modeling was used to quantify the behavior of the hydrogenation reactions. This study provides insights for optimizing catalyst selection and reaction conditions to improve the yield of hydrogenation products.
Article
Chemistry, Multidisciplinary
Yoichiro Kuninobu
Summary: Site-selective C-H transformations are important for achieving desired compounds efficiently. The development of practical methods for controlling site selectivity is highly desirable due to the difficulty of achieving such transformations. The most commonly used strategy is the directing group method, but it has limitations. Our group recently reported other methods using non-covalent interactions to achieve site-selective C-H transformations. This personal account explains the background, reaction design, and recently reported reactions in site-selective C-H transformations.
Article
Chemistry, Multidisciplinary
Nima Ronaghi, Elizabeth V. Jones, Hyun June Moon, Sang Jae Park, Christopher W. Jones, Stefan France
Summary: A new method has been discovered for the reaction of unprotected sugars with malononitrile to form bicyclic 2,3-dihydrofuran products with high yields and good selectivity. This method uses mild reaction conditions and a recyclable catalyst, making it suitable for carbohydrate upcycling.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Yehong Wang, Zhixin Zhang, Lijun Lei, Wen Liu, Shuyan Du, Xiangxue Zhu, Xiujie Li, Feng Wang
Summary: By controlling the defect concentrations of ceria supports over FeNi/ceria catalysts, selective C-H/C-C bond cleavage of propane with CO2 as the oxidant was achieved. Different defect concentrations in ceria supports led to distinct propane conversion selectivities, offering a new approach for the selective conversion of CO2 and alkanes.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Physical
Dengyun Miao, Xiulian Pan, Feng Jiao, Yi Ji, Guangjin Hou, Lei Xu, Xinhe Bao
Summary: The study reported an oxide-zeolite composite catalyst that enables the selective synthesis of para-xylene and light olefins from CO2 with renewable H-2, leading to higher yields of these valuable compounds. By modifying the zeolite with silica and phosphorus, the product selectivities can be significantly enhanced, providing a potential route for the synthesis of value-added chemicals using centralized greenhouse gas.
CATALYSIS SCIENCE & TECHNOLOGY
(2021)
Article
Polymer Science
Vincent Nieboer, Noe Fanjul-Mosteirin, Peter Olsen, Karin Odelius
Summary: In this study, a new selective catalyst for controlled ring-opening polymerization was explored. The catalyst showed high activity, good control, and stability in the polymerization of various lactones and cyclic carbonates. However, it could not polymerize lactones with substituents on the terminal carbon. This research is of great significance for the development of greener materials.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Won Seok Ham, Hoonchul Choi, Jianbo Zhang, Dongwook Kim, Sukbok Chang
Summary: This study describes a synthetic platform for site-selective C-H functionalization, which can be transformed into various amine products in situ. The method is compatible with a broad range of pyrimidines with sensitive functional groups and can access complex aminopyrimidines with high selectivity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Applied
Wei Sang, Yan-Yan Gong, Hua Cheng, Rui Zhang, Ye Yuan, Guang-Gao Fan, Zhi-Qin Wang, Cheng Chen, Francis Verpoort
Summary: A base-controlled protocol was developed for the C-N coupling of primary amines and 2-chlorobenzimidazoles, achieving selective synthesis of secondary or tertiary amines. The selectivity can be switched from monoarylation to diarylation by changing the base from iPr(2)NH to LiOtBu. The type, intrinsic basicity, and amount of bases utilized greatly affect the reactions.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Physical
Haoyi Lin, Jiaxing Zhang, Qingxu Duan, Kaixuan Yang, Weiping Liao, Shixue Qi, Hongying Lu, Zhiguo Zhu
Summary: This study successfully synthesized hierarchical Ti-Y zeolite catalysts with cooperative dual active sites through a dealumination-controlled strategy. The catalyst showed high catalytic activity in oxidative desulfurization and Baeyer-Villiger oxidation, demonstrating potential applications in constructing other heteroatom-containing FAU-type zeolites with Lewis acid property.
CATALYSIS SCIENCE & TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Meng Feng, Xia Zhou, Xirong Wang, Peipei Zhou, Jingyu Wang, Zhuoyi Cheng, Dongmei Wang
Summary: Based on the principles of reticular chemistry, two metal-organic frameworks (MOFs), PCP-33(Mn) and PCP-34(Mn), were assembled using two pyridine N-rich multifunctional triangular linkers and MnII. These MOFs exhibit high surface area and small windows, allowing for efficient gas capture and selective separation. They also serve as catalytic reactors for metal/solvent-free chemical fixation of CO2 with epoxides, demonstrating high conversion efficiency and recyclability.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Organic
Suresh Saini, Ramesh Bhawar, Avinash Kumar Srivastava, M. Siri, Kopal Garg, Shubhankar Kumar Bose
Summary: An efficient Lewis base-mediated protoboration of aromatic and aliphatic alkenes with B(2)pin(2) as the boron reagent is reported. This protocol demonstrates broad substrate scope and good functional-group tolerance on alkenes, giving high yields of synthetically useful alkyl boronate esters under mild reaction conditions. The gram-scale reaction further highlights the usefulness of this method.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Alberto Barranca, Iker Agirrezabal-Telleria, Marcos Rellan-Pineiro, Manuel A. Ortuno, Inaki Gandarias
Summary: The selective hydrogenolysis of C-OH bond without the hydrogenation of the furan ring is essential in converting biomass-derived platform chemicals. By adjusting the concentration of HCl during catalyst synthesis, the amount of surface chlorine can be fine-tuned, promoting the formation of 2-methylfuran and inhibiting undesired furan ring hydrogenation. Under optimized conditions, a yield of 94% 2-methylfuran and a productivity of approximately 18 mol(2MF) kg(cat)(-1) h(-1) were achieved.
REACTION CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Organic
Li-Jin Zhou, Kun Wang, Hong-Rong Guan, An-Qi Zheng, Hai-Tao Yang, Chun-Bao Miao
JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Chun-Bao Miao, An-Qi Zheng, Li-Jin Zhou, Xinyu Lyu, Hai-Tao Yang
Article
Chemistry, Organic
Kun Wang, Hong-Rong Guan, Wen-Long Ren, Hai-Tao Yang, Chun-Bao Miao
Summary: A copper-catalyzed cascade annulation reaction has been developed for the rapid synthesis of spiro-pentacyclic derivatives, forming five C-C/N/O bonds and an angular tricyclic core in one step under very mild conditions with excellent regioselectivity and stereoselectivity.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Chun-Bao Miao, Hai-Tao Yang, Hong-Rong Guan, YiHan Tang, Kun Wang, Wen-Long Ren, Xinyu Lyu, ChangSheng Yao
Summary: A novel copper-catalyzed bisannulation reaction was developed for the concise synthesis of structurally novel dihydroindolizine-fused pyrrolidinones and their analogues, showing excellent regioselectivity and stereoselectivity. The generated products can be easily functionalized through various reactions.
Article
Chemistry, Organic
Jitan Zhang, Manyi Wu, Hu Ju, Haitao Yang, Baiyang Qian, Ke Ding, Jiaping Wu, Meihua Xie
Summary: A silver-catalyzed, K2S2O8-mediated protocol has been developed for the regioselective acylarylation of unactivated alkenes, showing broad substrate scope and good tolerance of functional groups. This method allows for both internal and terminal alkenes to produce functional pyrrolo[1,2-a]indoles bearing the ketone carbonyl group, with the potential to construct structurally complex N-containing heterocycles.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Organic
Chun-Bao Miao, Xiao-Qi Qiang, Xiaoli Xu, Xiao-Qing Song, Su-Qing Zhou, Xinyu Lyu, Hai-Tao Yang
Summary: A copper-catalyzed annulation reaction of alpha,beta-unsaturated O-acyl ketoximes with isoquinolinium N-ylides was developed for the concise synthesis of stable N-H imines with a benzo[7,8]indolizine core. Cascade cyclization occurs when beta-(2-bromoaryl)-alpha,beta-unsaturated O-acyl ketoximes are used as the starting materials, leading to the formation of benzo[7,8]indolizino[1,2-c]-quinolines.
Article
Chemistry, Organic
Hai-Tao Yang, Su-Qing Zhou, Dan-Mei Chen, Zi-Jun Hu, Xiao-Qi Qiang, Xiao-Qing Song, Sheng Tan, Wei-Hua Jiang, Yong-Qiang Sun, Chun-Bao Miao
Summary: A copper-catalyzed annulation of O-acyl oximes with cyclic 1,3-diones has been developed, providing a concise synthesis of 7,8-dihydroindolizin-5(6H)-ones and cyclohexanone-fused furans through substituent-controlled selective radical coupling. 2-Alkyl cyclic 1,3-diones undergo C-C radical coupling, while 2-unsubstituted cyclic 1,3-diones undergo C-O radical coupling.
Article
Chemistry, Multidisciplinary
Xiao-Qing Song, Xiao-Qi Qiang, Zi-Jun Hu, Xinyu Lyu, Sheng Tan, Changsheng Yao, Yong-Qiang Sun, Chun-Bao Miao, Hai-Tao Yang
Summary: A concise method for the synthesis of 3-aryl-4-pyrrolin-2-ones was developed by copper-catalyzed [3+2] annulation of O-acyl ketoximes with 2-aryl malonates. The advantage of this method lies in the simultaneous generation of nucleophilic enamines and electrophilic p-quinone methides using O-acyl oximes as an internal oxidant. The subsequent nucleophilic addition selectively occurs on the a-C of malonates.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Jiaping Wu, Baiyang Qian, Lili Lu, Haitao Yang, Yongjia Shang, Jitan Zhang
Summary: The study presents a concise method for synthesizing structurally diverse indoles using Rh-III catalysis to enable switchable C2 C-H olefination and alkylation of N-quinolinyl indoles with alkenes, as well as highly efficient C-H deuteration. The reaction can be conducted under practical conditions with a broad substrate scope and good tolerance towards various functional groups. The potential value of this synthetic methodology is demonstrated by the diverse late-stage modification of the products, providing a straightforward route to access functionalized indoles, especially indole-based P,N ligands.
ORGANIC CHEMISTRY FRONTIERS
(2021)
