☆ 4.7 Article

Friedel-Crafts Arylation Reactions of N-Sulfonyl Aldimines or Sulfonamidesulfones with Electron-Rich Arenes Catalyzed by FeCl3•6H2O: Synthesis of Triarylmethanes and Bis-heteroarylarylmethanes

JOURNAL OF ORGANIC CHEMISTRY (2010)

期刊

JOURNAL OF ORGANIC CHEMISTRY

卷 75, 期 15, 页码 5240-5249

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AMER CHEMICAL SOC

DOI: 10.1021/jo1010137

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Chemistry, Organic

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Centre for Biological Modulators of the KRICT

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The FeCl3 center dot 6H(2)O-catalyzed Friedel-Crafts arylation reactions of N-sulfonyl aldimines or sulfonamidesulfones with electron-rich arenes and heteroarenes, which lead to the formation of triarylmethanes and bis-heteroarylarylmethanes, are developed. The use of mild reaction conditions, low catalytic loading, high yield, and single step synthesis are the advantages of the present procedure.

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