Article
Multidisciplinary Sciences
Song Xi, Jiawei Dong, Haohua Chen, Qiuyan Dong, Jiao Yang, Qiuyuan Tan, Changhui Zhang, Yu Lan, Min Zhang
Summary: The study presents a silver-catalyzed domino generation and [2,3]-sigmatropic rearrangement of ammonium ylides, leading to the stereoselective synthesis of chiral azabicycles with high enantiomeric purity (up to 99% ee). Experimental findings suggest that residual water in the reaction system plays a crucial role in facilitating the mild reaction conditions. In addition to silver salts, a stoichiometric amount of nonmetallic I-2 has also been successfully employed for the same reaction.
Article
Chemistry, Multidisciplinary
Qing-Qing Kang, Ya-Nan Meng, Jun-Hao Zhang, Long Li, Guo-Ping Ge, Hongxing Zheng, Hongxin Liu, Wen-Ting Wei
Summary: The iron-catalyzed oxidative cyclization reaction describes the reaction between olefinic 1,3-dicarbonyls and ketones to form potentially bioactive 2,3-dihydrofurans for the first time, with a broad substrate scope and ease of scale-up. The reaction pathway involves radical addition and intramolecular cyclization.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Xiaoyu Guo, Jinhuan Dong, Yunjie Zhu, Lan Bao, Zhongyan Hu, Xianxiu Xu
Summary: A Cu-catalyzed chemoselective heterocyclization of o-cinnamoyl arylisocyanides with alpha-substituted to-sylmethyl isocyanides is developed for the efficient synthesis of benzopyrroloazepinones. An isocyanide insertion into the C-Cu bond of organocuprate intermediate is involved in the formation of the seven-membered azepinone ring.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Organic
Fan Xiao, Peiqin Liao, Xiaoguang Lu, Jin Wang, Xiu-Qin Dong, Chun-Jiang Wang
Summary: In this study, an Ir-catalyzed asymmetric cascade reaction was successfully developed for the synthesis of chiral oxazinoindolone compounds with high efficiency. The method can be applied to pyrroles and other nitrogen-containing aromatic heterocycles. The reaction pathway was proposed based on preliminary mechanistic investigation. Importantly, the key intermediate for marine alkaloid (+)-agelastatin A can be readily accessed using this methodology.
Article
Chemistry, Multidisciplinary
Baohua Cai, Yuan Cui, Jian Zhou, Yong-Bin Wang, Limin Yang, Bin Tan, Jun (Joelle) Wang
Summary: A Cu/CPA co-catalytic system was developed to achieve direct hydrophosphinylation of alkynes with phosphine oxides, delivering novel axially chiral phosphorus-containing alkenes with high yields and excellent enantioselectivities (up to 99% yield and 99% ee). DFT calculations were performed to elucidate the reaction pathway and the origin of enantiocontrol. This streamlined and modular methodology establishes a new platform for the design and application of new axially chiral styrene-phosphine ligands.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Organic
Yangqing Zheng, Weichao Jiang, Jingbo Tan, Juzhang Yan, Ruoting Zhan, Huicai Huang
Summary: A highly efficient method for the beta, gamma-selective activation of deconjugated butenolides has been developed through an organocatalytic asymmetric vinylogous cascade reaction. This protocol enables the construction of a broad range of substituted tricyclic chroman-butyrolactones by vinylogous Michael/oxa-Michael pathways in good yield with good to high enantioselectivity and excellent diastereoselectivity. The ring-opening esterification of butyrolactones was also demonstrated.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Pavel A. Topanov, Anna A. Maslivets, Maksim V. Dmitriev, Irina V. Mashevskaya, Yurii V. Shklyaev, Andrey N. Maslivets
Summary: A novel heterocyclic compound has been synthesized using a simple method. This compound exhibits antimicrobial and antibiofilm activities.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Babar Hussain Shah, Sardaraz Khan, Can Zhao, Yong Jian Zhang
Summary: An efficient method for the synthesis of 2,3-dihydrofurans with a quaternary stereocenter has been developed through Pd-catalyzed asymmetric allylic cycloaddition and a retro-Dieckmann fragmentation cascade. The one-pot process involves the allylic cycloaddition of vinylethylene carbonates with 3-cyanochromone and subsequent base-assisted retro-Dieckmann fragmentation, leading to chiral 3,4-disubstituted 2,3-dihydrofurans with high yields and excellent enantioselectivities.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Chaoyang Song, Tingwei Shen, Lingzhu Chen, Tingting Li
Summary: A facile method was developed for the synthesis of structurally complex 2,3-naphthalimide derivatives. The reaction used readily available and inexpensive β-arylpropiolic acids and primary amines as starting materials. The reaction tolerated a wide range of substituents with different electronic and steric effects. The resulting 1-aryl-2,3-naphthalimide products showed promising applications in bactericide development for plant protections.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Mengyang Bai, Guanyu Tao, Zhenxing Liu, Lili Wang, Zheng Duan
Summary: A facile method for preparing mono-C-alkynyl-o-carboranes from o-carboranes and arylsulfonylacetylenes via one-pot reaction has been developed. This method tolerates a wide range of functional groups, operates under mild conditions, and has a short reaction time. The obtained mono-C-alkynyl-o-carboranes can be easily derivatized to synthesize other compounds.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Organic
Mingyue Cui, Juan Li, Rongqiang Tian, Zheng Duan
Summary: A straightforward synthetic method was developed using tandem [5 + 1] carbonyl cyclization/[8 + 2] cycloaddition reactions of tropones and phosphiranes to synthesize structurally complex 6,5,7-fused tricyclic scaffolds. This one-pot reaction showed excellent regio- and periselectivity, with exclusive formation of the P-O bond and high-order [8 + 2] cycloaddition enabled by the highly reactive C=P bond.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Organic
Nimisha Bania, Buddhadeb Mondal, Sounak Ghosh, Subhas Chandra Pan
Summary: In this study, unsaturated pyrazolones were used in the Rauhut-Currier reaction for the first time, leading to the successful synthesis of trisubstituted tetrahydropyrano[2,3-c]pyrazoles with excellent diastereoselectivities. The synthesis of disubstituted tetrahydropyrano[2,3-c]pyrazoles was also demonstrated, and a catalytic asymmetric version of the process was preliminarily studied using chiral DMAP catalysts.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Na Luo, Zhen-Wei Sun, Xing-Xin Xu, Xiao-Qiang Hu, Feng-Cheng Jia
Summary: A one-step, transition-metal-free, base-promoted cascade reaction of 2-halogenated arylglyoxals with 2-oxindoles provides a straightforward approach to structurally diverse N-protection free indole-indenones in satisfactory yields. Control experiments indicated the crucial role of the geminal bisindolin-2-one intermediate in the downstream annulation/ring-cleavage/ring-reconstruction reaction sequence. This novel reaction not only enriches the reactivity of indolin-2-ones as the recursive enolate anion source, but also achieves thermal-induced alpha-arylation of oxindoles without a transition-metal catalyst.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Organic
Wenwen Yu, Chao Chen, Lei Feng, Tianqi Xia, Chen Shi, Yaxi Yang, Bing Zhou
Summary: Through the screening and design of chiral ligands, a chiral rhodium-catalyzed asymmetric synthesis method has been developed for the preparation of various chiral compounds, with high efficiency and broad applicability.
Article
Chemistry, Organic
Afshin Yazdani-Elah-Abadi, Nasim Simin, Reza Morekian, Hadi Heydari-Dahoei
Summary: A novel methodology for the synthesis of spirooxindole-furo[2,3-c]pyrazole derivatives has been developed, involving a single-pot two-step four-component reaction catalyzed by triethylamine under microwave irradiation. This eco-friendly approach allows for efficient formation of new rings and bonds, with high yields and short reaction times, without the need for tedious workup or purification.
POLYCYCLIC AROMATIC COMPOUNDS
(2021)
Article
Chemistry, Physical
Chunlin Ye, Xujian Chen, Shasha Li, Binbin Feng, Yanghe Fu, Fumin Zhang, De-Li Chen, Weidong Zhu
Summary: Enhancing the selectivity of noble metal catalysts through electronic modulation is crucial for academic research and chemical industrial processes. The developed PdZn-ZnO/NCHS catalyst shows excellent catalytic performance for the semihydrogenation of 2-methyl-3-butyn-2-ol, with high activity and selectivity.
Article
Chemistry, Physical
Yufeng Gong, Ruixin Liu, Lingyan Jiang, Anna Peng, Chunhui Xu, Xinqing Lu, Rui Ma, Yanghe Fu, Weidong Zhu, Shuhua Wang, Liyang Zhou
Summary: In this study, a series of Al-doped MgF2 materials were synthesized and used as supports to prepare RuO2/Al-MgF2 catalysts. It was found that at an optimal calcination temperature, Al could be incorporated into the framework of MgF2, enhancing the activity and stability of the catalyst.
Article
Chemistry, Physical
Wenting Lin, Yaping Song, Li Wang, Nan Li, Yanghe Fu, De-Li Chen, Weidong Zhu, Fumin Zhang
Summary: In this study, Pd/Ce-MOF-801 catalyst was prepared using an incipient wetness impregnation strategy and its physicochemical properties were investigated. The results showed that Pd/Ce-MOF-801 exhibited high catalytic performance in the Suzuki-Miyaura cross-coupling reaction and had good recyclability and tolerance to various substrates.
Article
Environmental Sciences
Yuexian Du, Guang'an Jie, Huilin Jia, Jiahui Liu, Jieyu Wu, Yanghe Fu, Fumin Zhang, Weidong Zhu, Maohong Fan
Summary: The photocatalytic technology of reducing CO2 into high value-added chemicals and fuels can mitigate energy shortages and environmental problems caused by greenhouse effects. This study successfully improved the photocatalytic performance of Zr-MOF for CO2 reduction by covalent modification, demonstrating the potential of modifying MOFs to enhance the photocatalytic efficiency of CO2 reduction.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Yu Zhao, Saikat Das, Taishu Sekine, Haruna Mabuchi, Tsukasa Irie, Jin Sakai, Dan Wen, Weidong Zhu, Teng Ben, Yuichi Negishi
Summary: The unique structural characteristics of three-dimensional (3D) covalent organic frameworks (COFs) make them promising platforms for various functional applications. In this study, we successfully designed and synthesized a 3D non-interpenetrated stp net COF named TUS-64 with the largest pore size and record-low density. TUS-64 exhibits high stability and a highly interconnected mesoporous structure, enabling efficient drug loading and controlled release in a simulated body fluid environment.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Letter
Chemistry, Multidisciplinary
Guolong Xing, Shuai Zhang, Weidong Zhu, Teng Ben
Summary: White et al. provided additional structural data in a recent Correspondence, showing that CPOS-6 undergoes a single-crystal-to-single-crystal transformation during water adsorption/desorption. This finding improves our understanding of the experimental phenomena and complements our previous results. However, it is important to note that our research focuses on the kinetic behavior of ultrafast adsorption/desorption of water in nano-confined channels and the interpretation of rapid water transport from the perspective of superfluidity.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Yaping Song, Ruifang Xue, Li Wang, Nan Li, Zhijun Fang, Yanghe Fu, De-Li Chen, Weidong Zhu, Fumin Zhang
Summary: A chemoselective reductive heterocyclization route is used for direct synthesis of 2,1-benzisoxazole and related compounds. The transformation of feedstocks using hydrogen as a hydrogen source at ambient temperature and atmospheric pressure remains a challenge.
Article
Chemistry, Physical
Nan Li, Changping Jian, Yaping Song, Li Wang, Ata Ur Rehman, Yanghe Fu, Fumin Zhang, De-Li Chen, Weidong Zhu
Summary: Here, a facile and scalable approach for synthesizing Fe-based MOF MIL-88A(Fe) via a liquid-phase route at atmosphere pressure is reported. The synthesized MIL-88A(Fe) nanocrystals exhibit high crystallinity, monodispersed particle size, and large specific surface area. These nanocrystals serve as a heterogeneous catalyst for the efficient aerobic oxidation of cyclohexene to 2-cyclohexene-1-ol with high conversion (81%) and selectivity (70%). The reaction mechanism involves both free radical and Fe-mediated pathways.
MOLECULAR CATALYSIS
(2023)
Article
Engineering, Environmental
Yaping Song, Rou Guo, Binbin Feng, Yanghe Fu, Fumin Zhang, Yifei Zhang, De-Li Chen, Jiangwei Zhang, Weidong Zhu
Summary: A facile strategy to modulate the coordination number of Zn single atoms and enhance the catalytic activity for transfer hydrogenation was reported. The Zn-N3 coordination in the catalyst exhibited the best performance.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Environmental Sciences
Ke Guo, Ijaz Hussain, Guang'an Jie, Yanghe Fu, Fumin Zhang, Weidong Zhu
Summary: This review discusses the recent breakthroughs in photocatalytic CO2 reduction, focusing on the use of metal-organic frameworks (MOFs) as new catalysts. Various techniques for modifying MOFs and integrating them with other materials have been explored and summarized. The challenges and future prospects of MOFs as photocatalysts for CO2 reduction are also discussed.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Chemistry, Physical
Huilin Jia, Baihui Zhu, Xiaoyan Zhi, Yuexian Du, Jiahui Liu, Guang'an Jie, Yanghe Fu, Rui Ma, Fumin Zhang, Weidong Zhu
Summary: As a new type of porous organic materials, two-dimensional covalent organic frameworks (2D COFs) show superior visible-light harvesting and effective separation and transport of the photogenerated charges, which ensures COFs to be promising platforms for photocatalysis. In this study, two 2D imine-linked COFs (PDA-TAB and PDA-TTA) were synthesized to investigate the effects of the introduced triazine units in the skeleton of COFs on photocatalytic CO2 reduction. The results showed that PDA-TTA exhibited a much higher photocatalytic activity compared to PDA-TAB, with a HCOOH yield of 65.7 mu mol g(cat)(-1)h(-1). Further studies indicated that the introduction of triazine units in the skeleton of PDA-TTA not only enhanced the visible-light absorption but also promoted the charge separation and migration, thereby improving the photocatalytic performance. This work contributes to the understanding of the roles of key structural units in 2D COFs in photocatalysis and provides insights for the development of efficient photocatalysts for CO2 conversion.
Article
Chemistry, Physical
Yuexia Wang, Qibin Yao, Bowen Xu, Kehang Lin, Mengshan Deng, Xinqing Lu, Rui Ma, Yanghe Fu, Weidong Zhu
Summary: The acid-modulated isomorphous substitution method is developed to synthesize Ti-MWW zeolite without extra-framework octahedral Ti species, leading to higher ethylene glycol (EG) yield and H2O2 utilization efficiency compared to the prevailing methods. The Ti-MWW zeolite prepared by this method has more open Ti(OSi)3OH sites, resulting in stronger Lewis acidity, which is beneficial for EG production. Moreover, the catalyst is recyclable after regeneration by high-temperature calcination, indicating its potential industrial application in the one-pot synthesis of EG from ethylene with H2O2.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Jie Chen, Mingyuan Jian, Lei Zhuang, Wenting Lin, Yanghe Fu, De-Li Chen, Weidong Zhu, Guihua Chen, Fumin Zhang
Summary: A series of N-doped porous carbon-supported CeO2 and ZrO2 nanoparticle catalysts were prepared, and CeZr-NC-1073 showed outstanding catalytic activity and stability.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Engineering, Environmental
Weilong Hou, Kehang Lin, Xiangyu Zhang, Bowen Xu, Yuexia Wang, Xinqing Lu, Yijing Gao, Rui Ma, Yanghe Fu, Weidong Zhu
Summary: This study developed efficient catalysts for nonoxidative propane dehydrogenation (PDH) and demonstrated that the stability and selectivity for propylene of the catalysts were significantly enhanced. The catalysts also showed no sintering at high temperatures, providing a strategy for practical applications.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Xiaoxue Wu, Wenting Lin, Li Wang, Nan Li, Gaomei Tu, Yanghe Fu, De-Li Chen, Weidong Zhu, Guihua Chen, Fumin Zhang
Summary: In this study, highly dispersed Pd nanoclusters anchored on HfO2 support were fabricated as catalysts and showed excellent catalytic activity and stability for the Suzuki-Miyaura coupling reaction, indicating significant potential for industrial application.
NEW JOURNAL OF CHEMISTRY
(2022)
