期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 14, 页码 4686-4695出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo100884u
关键词
-
资金
- Fonds der Chemischen Industrie
- Deutsche Forschungsgemeinschaft (DFG)
- European Research Council (ERC)
A broad range of functionalized aryl- and heteroarylzinc reagents were prepared via directed zincation of sensitive and moderately activated aromatics and heteroaromatics using TMPZnCl center dot LiCl under various reaction conditions. Diverse sensitive functional groups such as a nitro group, an aldehyde, an ester, and a nitrile are readily tolerated and are compatible with high metalation temperatures. Furthermore, the resulting zinc organometallics display an excellent reactivity toward various classes of electrophiles providing functionalized aromatics and heteroaromatics in high yields.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据