4.7 Article

Synthesis of an Acyltrifluoroborate and Its Fusion with Azides To Form Amides

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JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 12, 页码 4304-4306

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AMER CHEMICAL SOC
DOI: 10.1021/jo1004058

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  1. Qatar National Research Fund [08-035-1-008]
  2. NIH [R01 GM-081376]
  3. Merck Research Laboratories

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A uniquely stable acyl potassium trifluoroborate, potassium (2-phenylacetyl)trifluoroborate, has been synthesized and isolated. In the presence of an activating Lewis acid, this reagent reacts with asides to form amides in good yields.

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