Imidazolium Cation Supported Solution-Phase Assembly of Homolinear α(1→6)-Linked Octamannoside: An Efficient Alternate Approach for Oligosaccharide Synthesis

An efficient, simple convergent assembly of a homolinear alpha(1 -> 6)-linked octamannosyl thioglycoside was obtained starting from imidazolium cation-tagged mannosyl fluoride and thiomannoside using block couplings. During chain elongation glycosylation reactions no column chromatographic purifications were used.