Article
Chemistry, Organic
Yuki Ohishi, Junya Chiba, Masahiko Inouye
Summary: We successfully created chiral assemblies of macrocycles through saccharide recognition, and the experimental results showed that the chirality of the guest saccharides affects the helical sense of the macrocycles.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Hye Jin Jang, Seungwon Lee, Byung Jun An, Geunmoo Song, Hae-Geun Jeon, Kyu-Sung Jeong
Summary: A new aromatic foldamer has been synthesized, featuring helical conformations stabilized by dipole-dipole interactions and pi-stacking. This foldamer has been further modified into a synthetic receptor with a tweezer-type binding cavity, in contrast to most aromatic foldamers with internal binding cavities.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Christopher A. Ryan, Vladislavs Baskevics, Martins Katkevics, Eriks Rozners
Summary: In triplex-forming peptide nucleic acid, a novel 2-guanidyl pyridine nucleobase (V) can recognize up to two cytosine interruptions in polypurine tracts of dsRNA by engaging the entire Hoogsteen face of C-G base pair. Insights from ab initio and molecular dynamics simulations revealed the H-bonding interactions that stabilize V · C-G triplets. Our findings provide guidance for future design of improved nucleobases, advancing the goal of recognizing any sequence of dsRNA.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Siqi Zhang, Chen Chen, Jianqiao Li, Chunyu Ma, Xiaokang Li, Wei Ma, Min Zhang, Faliang Cheng, Ke Deng, Qingdao Zeng
Summary: The supramolecular self-assembly behavior of a low-symmetric aromatic carboxylic acid molecule and its co-assembly behavior with a series of pyridine molecules were studied at the liquid-solid interface. It was found that the pyridine molecules were able to regulate the self-assembly structure of the carboxylic acid molecule, and the molecular arrangement of the co-assembled structures varies with the shape of the pyridine molecules.
Article
Biochemistry & Molecular Biology
Sanghun Lee, Fuyou Fu, Chao-Jan Liao, Demeke B. Mewa, Adedayo Adeyanju, Gebisa Ejeta, Damon Lisch, Tesfaye Mengiste
Summary: This study identified a major fungal resistance locus in sorghum, consisting of the immune receptor gene ARG1, which confers broad-spectrum resistance to fungal pathogens by regulating CARG expression and histone methylation.
Article
Chemistry, Inorganic & Nuclear
Wen-Ze Zhang, Ruo-Yu Li, Peng Li, Zhuang-Zhuang Chen, Wen-Kui Dong
Summary: A novel sensor PNS was synthesized for the continuous recognition of Cu2+ and S2-, with low LOD values, by fluorescence emission spectroscopy in a DMSO/H2O solution.
INORGANICA CHIMICA ACTA
(2021)
Article
Biochemistry & Molecular Biology
Ankit Maurya, Pradeep Sharma, Prashant K. Singh, V. Viswanathan, Punit Kaur, Sujata Sharma, Tej P. Singh
Summary: The short peptidoglycan recognition protein (PGRP-S) of the innate immune system recognizes invading microbes through binding to their cell wall molecules. The structure of the complex of camel PGRP-S (CPGRP-S) with hexanoic acid reveals how PGRP-S binds to bacterial cell wall molecules.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2023)
Article
Computer Science, Information Systems
Mengjian Zhang, Guihua Wen, Jiahui Zhong, Dongliang Chen, Changjun Wang, Xuhui Huang, Shijun Zhang
Summary: In this study, a novel convolution complex transformation MLP-like (CCT-MLP) model is proposed for the multi-label disease location (DL) and disease nature (DN) recognition task of facial and tongue images. The model extracts shallow features using convolutional Tokenizer and multiple convolutional layers, and deep-level contextual features using the Channel-MLP architecture with complex transformations, achieving better performance in multi-label classification.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2023)
Article
Chemistry, Multidisciplinary
Hajime Abe, Tetsuhiro Yoneda, Yuki Ohishi, Masahiko Inouye
CHEMISTRY-A EUROPEAN JOURNAL
(2016)
Article
Chemistry, Organic
Hajime Abe, Ryuta Yumoto, Masahiko Inouye
Article
Chemistry, Organic
Shu Hirokane, Shunsuke Takashima, Hajime Abe, Masahiko Inouye
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2017)
Article
Chemistry, Organic
Yuki Ohishi, Hajime Abe, Masahiko Inouye
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2017)
Article
Chemistry, Organic
Hajime Abe, Shunsuke Takashima, Masahiko Inouye
Article
Chemistry, Organic
Hajime Abe, Chihiro Sato, Yuki Ohishi, Masahiko Inouye
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Organic
Hajime Abe, Daisuke Hashikawa, Takaya Minami, Kohei Ohtani, Kentaro Masuda, Shinya Matsumoto, Masahiko Inouye
JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Organic
Yuki Ohishi, Naoto Yamamoto, Hajime Abe, Masahiko Inouye
JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Organic
Tomoya Hayashi, Yuki Ohishi, So Hee-Soo, Hajime Abe, Shinya Matsumoto, Masahiko Inouye
JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Medicine, Research & Experimental
Yuri Kinoshita, Kagayaki Nogami, Ryuta Jomura, Shin-ichi Akanuma, Hajime Abe, Masahiko Inouye, Yoshiyuki Kubo, Ken-ichi Hosoya
MOLECULAR PHARMACEUTICS
(2018)
Review
Pharmacology & Pharmacy
Hajime Abe
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
(2019)
Article
Chemistry, Organic
Yuki Ohishi, Mikino Murase, Hajime Abe, Masahiko Inouye
Article
Chemistry, Organic
Tomoya Hayashi, Yuki Ohishi, Hajime Abe, Masahiko Inouye
JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Yuki Ohishi, Kentaro Masuda, Kazuki Kudo, Hajime Abe, Masahiko Inouye
Summary: Cage-shaped hosts and three-arm-shaped hosts exhibit strong binding to saccharides, with the latter being easier to prepare. Both types of hosts can form chiral complexes with high association constants and extract native monosaccharides into a lipophilic solvent.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Daiki Suzuki, Hajime Abe, Takaya Minami, Shinya Matsumoto, Masahiko Inouye