期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 73, 期 17, 页码 6853-6856出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo8012385
关键词
-
资金
- Kanel Foundation
- NSF [CMMI-072870, CTS-0608889]
From quantum mechanics calculations we confirm that the naturally occurring enol lancifodilactone G is stable over the keto form (by 2.6 kcal/mol in water), the only known stable aliphatic enol (devoid of conjugated or bulky aromatics and lacking a 1,3-diketone structural motif known to stabilize enols). We determine architectural elements responsible for the enol stabilization and find a mechanism for keto-enol conversion in solution. In addition, we correct previously reported computational results that were performed on the misinterpreted Structure demonstrating that the enol form of this natural product is more stable than previously thought.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据