4.1 Article

Early Screening in Patients With Head and Neck Cancer Identified High Levels of Pain and Distress

期刊

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
卷 71, 期 8, 页码 1458-1464

出版社

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.joms.2013.02.009

关键词

-

向作者/读者索取更多资源

Purpose: Pain and distress are recognized as the fifth and sixth vital signs in cancer care, respectively, as debilitating symptoms that are frequently under-recognized. The aim of this study was to document, using touch-screen technology, levels of pain and distress in patients with head and neck cancer before their assessment at a head and neck multidisciplinary referral clinic. Materials and Methods: A cross-sectional study over a 4-year period (2008 through 2011) was conducted for patients attending a head and neck oncology multidisciplinary team clinic in the Hunter New England referral district of Australia. Predictor variables were cancer stage and site. Cancer sites divided into 8 different regions, with distinction made for cutaneous versus noncutaneous sites. Outcome variables consisted of pain and distress levels. Pain was assessed using a Numerical Rating Scale of 0 to 10, and distress was assessed using the Distress Thermometer and PSYCH-6 scales. In the context of a screening study and for statistically comparing pain with other variables, pain was regarded as any score higher than 0. Clinically significant distress represented a Distress Thermometer score higher than 3 and a PSYCH-6 score of at least 3. Data analysis consisted of descriptive statistics, variance contrasts, and 2-tailed Pearson correlations. Results: Four hundred thirty-six patients were included in the study, with an equal number of cutaneous and noncutaneous cancer sites. Thirty-four percent of patients reported having pain, and 13% had clinically significant distress. Tumor stage did not significantly affect pain or distress scores. Conclusions: There is a high level of pain and distress reported by patients with head and neck cancer before their assessment and management is discussed. Crown Copyright (C) 2013 Published by Elsevier Inc on behalf of the American Association of Oral and Maxillofacial Surgeons. All rights reserved

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.1
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Dermatology

Saggy skin as a presenting sign of angioimmunoblastic T-cell lymphoma

N. G. Maher, Y. Z. Chiang, X. Badoux, L. W. Vonthethoff, D. F. Murrell

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2016)

Review Oncology

In vivo confocal microscopy for the oral cavity: Current state of the field and future potential

N. G. Maher, H. Collgros, P. Uribe, S. Ch'ng, M. Rajadhyaksha, P. Guitera

ORAL ONCOLOGY (2016)

Article Dermatology

Detection of desmoplastic melanoma with dermoscopy and reflectance confocal microscopy

N. G. Maher, A. Solinas, R. A. Scolyer, S. Puig, G. Pellacani, P. Guitera

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2017)

Article Dentistry, Oral Surgery & Medicine

In vivo reflectance confocal microscopy for evaluating melanoma of the lip and its differential diagnoses

Nigel G. Maher, Annalisa Solinas, Richard A. Scolyer, Pascale Guitera

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY (2017)

Article Dentistry, Oral Surgery & Medicine

Anaphylaxis: an update for dental practitioners

N. G. Maher, J. de Looze, G. R. Hoffman

AUSTRALIAN DENTAL JOURNAL (2014)

Article Dentistry, Oral Surgery & Medicine

Head and Neck Cutaneous Squamous Cell Carcinoma Metastatic to Cervical Sublevel IIb Lymph Nodes Occurred From Primary Sites Involving the Auricle and Adjacent Neck

Nigel Gordon Maher, Gary Russell Hoffman

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2014)

Article Dentistry, Oral Surgery & Medicine

Elective Neck Dissection for Primary Oral Cavity Squamous Cell Carcinoma Involving the Tongue Should Include Sublevel IIb

Nigel Gordon Maher, Gary Russell Hoffman

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2014)

Article Surgery

Acinic cell carcinoma of the salivary gland in the adult and paediatric population: a survival analysis

Anders Sideris, Amshuman Rao, Nigel Maher, Andrew Parker, Julia Crawford, Robert Smee, Ian Jacobson, Richard Gallagher

Summary: Acinic cell carcinoma (AcCC) is a rare malignant neoplasm of the salivary glands, with surgery as the first-line treatment showing excellent survival outcomes. The clinico-pathological features and treatment methods are associated with survival results, with certain high-risk factors linked to poor survival outcomes.

ANZ JOURNAL OF SURGERY (2021)

Article Pathology

Genomic Profiling of Metastatic Basal cell Carcinoma Reveals Candidate Drivers of Disease and Therapeutic Targets

Ismael A. Vergara, Karina Aivazian, Matteo S. Carlino, Alexander D. Guminski, Nigel G. Maher, Kerwin F. Shannon, Sydney Ch'ng, Robyn P. M. Saw, Georgina Long, James S. Wilmott, Richard A. Scolyer

Summary: Basal cell carcinomas (BCCs) are the most common malignant tumors in humans and are usually easily managed by surgery or topical therapies. However, metastatic BCCs are rare and may have distinct biological characteristics. Through genomic profiling, aberrant activation of Hedgehog signaling and alterations in multiple signaling pathways were identified in metastatic BCCs. The presence of clonal origin in matched local recurrences and metastases suggests that molecular profiling can assist in determining the nature and origin of poorly differentiated metastatic tumors. Dysregulation of the Hippo and PI3K/AKT pathways were implicated in the metastatic progression of BCCs, making them potential therapeutic targets.

MODERN PATHOLOGY (2023)

Article Pathology

Biology and genetics of acquired and congenital melanocytic naevi

Nigel G. Maher, Richard A. Scolyer, Andrew J. Colebatch

Summary: Acquired and congenital melanocytic naevi are common benign neoplasms, and understanding their biology and genetics can help diagnose melanocytic tumours correctly and gain insights into naevus aetiology and melanomagenesis.

PATHOLOGY (2023)

Article Pathology

Inter-rater concordance of basal cell carcinoma subtypes: influences on reporting format and opportunities for further classification modifications

Nigel G. Maher, Natasha Prosser, Karina Aivazian, Andrew J. Colebatch, Peter M. Ferguson, Rooshdiya Z. Karim, Catriona A. Mckenzie, Robert V. Rawson, Serigne N. Lo, Richard A. Scolyer

Summary: This study compares the interobserver reproducibility of individual subtypes of basal cell carcinoma (BCC) using the 4th edition World Health Organization (WHO) Classification of Skin Tumours (CoST) definitions. The results show that some BCC subtypes have high interobserver agreement, while others have moderate agreement. The study suggests the need for more precise definitions of BCC subtypes and recommends reporting BCC subtypes using a two-tiered risk grouping method.

PATHOLOGY (2023)

Article Oncology

Lag-3 expression and clinical outcomes in metastatic melanoma patients treated with combination anti-lag-3+anti-PD-1-based immunotherapies

Tuba N. Gide, Elizabeth C. Paver, Zarwa Yaseen, Nigel Maher, Nurudeen Adegoke, Alexander M. Menzies, Ines Pires da Silva, James S. Wilmott, Georgina V. Long, Richard A. Scolyer

Summary: This study evaluated the association between LAG-3 expression and clinical outcomes in metastatic melanoma patients treated with anti-LAG-3 and anti-PD-1 immunotherapy. The results showed that LAG-3 expression was related to treatment response and tumor-infiltrating lymphocytes, and patients with ≥ 1% LAG-3+ cells had longer progression-free survival.

ONCOIMMUNOLOGY (2023)

Letter Dermatology

Imiquimod treatment for lentigo maligna: LIMIT-1 trial

N. G. Maher, P. Guitera

BRITISH JOURNAL OF DERMATOLOGY (2017)

Letter Dermatology

Melanoma diagnosis may be a pitfall for optical coherence tomography assessment of equivocal amelanotic or hypomelanotic skin lesions

N. G. Maher, T. P. Blumetti, E. E. Gomes, H. M. Cheng, L. Satgunaseelan, S. Lo, G. G. Rezze, R. A. Scolyer, P. Guitera

BRITISH JOURNAL OF DERMATOLOGY (2017)

暂无数据