Article
Cell Biology
Joo-Yul Bae, Suk Young Park, Young Ho Shin, Shin Woo Choi, Jae Kwang Kim
Summary: Animal studies have shown that using amphoteric detergent and nuclease is the most reliable method for decellularizing peripheral nerves. This method successfully removes cellular components and preserves extracellular matrix integrity, outperforming nonionic and anionic detergents. Additionally, the decellularized nerves are biocompatible and maintain comparable biomechanical properties to fresh controls.
NEURAL REGENERATION RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Nhan Van Vo, Tu Nguyen, Quan Dong Ta, Bao Chi Truong
Summary: This case report describes a unique case of implant treatment in a patient with unilateral reconstructed mandible, involving contralateral inferior alveolar nerve transposition and iliac onlay bone grafting. Despite the challenges, successful long-term outcomes were achieved with appropriate perioperative and postoperative care.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Engineering, Biomedical
Nan Jiang, Haozhe Chen, Jie Zhang, Pinyin Cao, Peng Wang, Yi Hou, Peijie Tan, Jialin Sun, Zhen Li, Songsong Zhu
Summary: A prosthesis construct mimicking the natural TMJ disc was developed using laser-drilled decellularized natural disc and polycaprolactone reinforcement. It demonstrated good bio-compatibility, safety, and immunological tolerance, and maintained its integrity and mechanical properties during long-term implantation. This study provides a potential treatment option for TMJ disc-related diseases.
ACTA BIOMATERIALIA
(2023)
Article
Surgery
A. Manfuso, A. Pansini, K. Tewfik, C. Copelli
Summary: The inferior alveolar nerve (IAN) is a sensitive branch of the mandibular nerve innervating the lower lip, the chin, the buccal mucosa and the teeth. Lesions of the IAN during maxillo-facial procedures can cause anesthesia, hypoestesia, and neurogenic discomfort, but nervous grafts can be used to restore nerve continuity.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2021)
Review
Health Care Sciences & Services
Yangjie Li, Ziji Ling, Hang Zhang, Hanyu Xie, Ping Zhang, Hongbing Jiang, Yu Fu
Summary: The study aimed to compare the relationship between the buccal and lingual positions of the inferior alveolar nerve canal relative to the lower third molar and the rate of inferior alveolar nerve injury. The results showed that the inferior alveolar nerve canal located lingually of the lower third molar roots had a higher risk of nerve damage during third molar extraction.
Article
Medicine, Research & Experimental
Chloe Capon, Aurelien Crevant, Armelle Pointin, Arek Sulukdjian, Nathan Moreau
Summary: This article reports a case of painful post-traumatic trigeminal neuropathy and investigates the effectiveness of local injections of botulinum toxin type A. By administering BTX-A injections in the vicinity of the affected nerves, significant improvement in the patient's condition and quality of life was achieved.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2022)
Article
Anesthesiology
Aneurin Moorthy, Stephen Choi, Ben Safa, Paul G. McHardy, Ahtsham U. Niazi
Summary: Pubic rami fractures are common injuries, particularly in elderly individuals with osteoporosis, following high-speed trauma. Traditional treatment involves conservative and non-operative management, focusing on pain relief for early mobilization and hospital discharge. However, analgesic options are limited and regional anesthesia techniques are restricted.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Multidisciplinary Sciences
Magdalena Koszewicz, Dorota Kaminska, Jacek Martynkiewicz, Adam Domanasiewicz, Jerzy Gosk
Summary: This study presents a case of peripheral neurological complications following SARS-CoV-2 infection, specifically selective sciatic nerve demyelination. The patient showed significant clinical and electrophysiological improvement after receiving a right sciatic nerve allo-transplantation and intravenous immunoglobulin treatment. These findings suggest that the inflammatory immune process may play a role in the development of peripheral demyelination.
Article
Medicine, General & Internal
Jun-Mo Park, Seong-Min Hwang
Summary: In patients with terminal cancer, CT-guided inferior mesenteric plexus block can be performed to alleviate left-sided lower abdominal pain more safely and accurately, especially when severe pain or anatomical deformation present challenges.
Review
Dentistry, Oral Surgery & Medicine
Gustavo Matus, Juan Pablo Aravena, Dylan Marino, Sven Eric Niklander
Summary: This systematic review aimed to evaluate the efficacy of decellularized allografts for the treatment of inferior alveolar nerve (IAN) damage. The results showed that in all six articles, more than 85% of patients achieved resolution of IAN damage after a 12-month follow-up, and in two articles, complete resolution was observed in 100% of patients at longer follow-ups.
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL
(2023)
Article
Engineering, Biomedical
Jorge Alfredo Uquillas, Janne Spierings, Antonio van der Lande, Aysegul Dede Eren, Manon Bertrand, Hao Yuan, Huipin Yuan, Bart van Groningen, Rob Janssen, Keita Ito, Jan de Boer, Jasper Foolen
Summary: This study proposes the use of decellularized bone-ACL-bone allografts as an alternative to autografts in ACL reconstruction. The results show that the decellularized allografts have similar mechanical properties to the native ACL, maintain similar collagen content, and do not cause cytotoxicity to tendon-derived cells.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Medicine, General & Internal
Liang-Wen Chen, Xiao-E Zhao, Qi Yan, Hai-Bin Xia, Quan Sun
Summary: This article introduces a trans-IAN implant placement technique guided by a dynamic navigation system, which can successfully treat posterior mandibular dentition defects with a bone height of only 4.5 mm, and the restoration outcome is stable.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Biotechnology & Applied Microbiology
Yan Kong, Di Wang, Qufu Wei, Yumin Yang
Summary: In this study, a porous NDM-CS scaffold with high antimicrobial activity and high biocompatibility was prepared. The scaffold not only promoted nerve regeneration but also prevented wound infection. The positive effect on Schwann cells indicated its potential in nerve injury repair.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Biomedical
Binghui Jin, Yunru Yu, Xiangxiang Chen, Yanhong Yang, Yushan Xiong, Young Jun Im, Yuanjin Zhao, Jian Xiao
Summary: The study proposes a novel microtube for sciatic nerve regeneration using gradient decellularized porcine sciatic nerve extracellular matrix hydrogel (pDScNM-gel). The pDScNM is shown to enhance cell proliferation and migration, improve axon growth, and these effects can also be achieved through coculture in a gradient pDScNM microtube. In vivo sciatic nerve regeneration and functional recovery are demonstrated by assembling the gradient pDScNM microtubes with a medical silicon tube.
BIOACTIVE MATERIALS
(2023)
Article
Endocrinology & Metabolism
D. Guerra, M. D'Amario, M. Lacarbonara, S. Rastelli, E. Lupi, M. Capogreco
Summary: As technology advances, the field of medicine, including dentistry, has been able to improve patient comfort and treatment outcomes. The development of implantology has allowed patients to achieve higher levels of comfort, even in complex cases. Radiographic advancements have provided precise tissue evaluation and the possibility of three-dimensional reproduction, aiding in communication between professionals and patients.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
