Article
Oncology
Jorge Pamias-Romero, Manel Saez-Barba, Alba de-Pablo-Garcia-Cuenca, Pablo Vaquero-Martinez, Joan Masnou-Pratdesaba, Coro Bescos-Atin
Summary: This study evaluated the health-related quality of life in patients undergoing mandibular reconstruction using free fibula flap and titanium customized plates. Results showed that the highest scores were obtained in taste, shoulder function, anxiety, and pain. The lowest scores corresponded to chewing, appearance, saliva, and mood. Most patients rated their overall quality of life as good, very good, or outstanding. This study demonstrates that reconstructing the mandible using computer-aided design and manufacturing technology can improve the health-related quality of life.
Article
Cell & Tissue Engineering
Yongfeng Li, Huawei Liu, Chao Wang, Rongzeng Yan, Lei Xiang, Xiaodan Mu, Lingling Zheng, Changkui Liu, Min Hu
Summary: This study aimed to fabricate 3D-printing titanium grid scaffolds to achieve bone fusion in mandibular segmental defects. The results showed that the scaffolds with sufficient pores and basic biomechanical strength could facilitate bone regeneration and integration of bone broken ends. Clinical observations on both animal models and patients confirmed the successful bone regeneration in mandibular defects using the titanium grid scaffolds.
NPJ REGENERATIVE MEDICINE
(2023)
Review
Otorhinolaryngology
Patrick Tassone, Stephanie Clookey, Michael Topf, Tabitha Galloway, Laura Dooley, Robert Zitsch
Summary: This systematic review found that patients with ONJ had worse quality-of-life compared to the general population and head and neck cancer patients without ONJ. Segmental mandibulectomy and bony free flap reconstruction improved quality of life in some patients.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2022)
Article
Multidisciplinary Sciences
Ning Gao, Kun Fu, Jinghua Cai, Wei He
Summary: This study aimed to investigate and compare the quality of life of patients who underwent fibula flap and iliac flap surgeries to repair mandibular defects at 6 and 24 months post-surgery. The results showed that the fibula flap surgery improved speech, diet, social contact, and teeth function, while the iliac flap surgery significantly reduced functional limitations.
SCIENTIFIC REPORTS
(2023)
Article
Surgery
Sho Yamakawa, Kenji Hayashida
Summary: In this study, the safety and efficacy of secondary mandibular reconstruction using FFF were evaluated and found to be comparable to primary reconstruction. Complete flap survival was achieved in the secondary reconstruction group, indicating that it can be a viable option for mandibular reconstruction.
Article
Surgery
Michael Bolliger, Pia Lanmueller, Michael Schuetz, Bernhard Heilig, Amadeus Windischbauer, Raimund Jakesz, Tanja Zehetgruber, Michael Gnant, Andreas Gleiss, Daniela Doerfler, Christian Singer, Rupert Bartsch, Werner Haslik, Giacomo Montagna, Florian Fitzal
Summary: This study aimed to compare the quality of life in patients undergoing oncoplastic surgery, conventional breast conservation, or mastectomy. The results showed that oncoplastic breast conservation can achieve a similar quality of life as conventional breast conservation.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Oncology
Henriette L. Moellmann, Laura Apeltrath, Nadia Karnatz, Max Wilkat, Erik Riedel, Daman Deep Singh, Majeed Rana
Summary: This study compared the accuracy of mandibular reconstruction and clinical outcomes between conventional reconstruction plates (CR) and patient-specific implants (PSI). The results showed no significant differences in reconstruction accuracy and postoperative complications between the two methods, but there were some discrepancies at specific measurement points.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Khanh Linh Tran, Matthew Lee Mong, James Scott Durham, Eitan Prisman
Summary: This study compares the accuracy of patient-specific reconstructive plates (PSRP) and manually contoured plates in mandibular reconstruction. The results show significant differences between reconstructions performed with PSRP and manually contoured plates in plate-mandible distance, inter-fibular segment gap, mandible-fibula gap, reconstruction deviation, mandibular angle width difference, and reconstruction time. A lower plate-mandible distance is associated with decreased plate extrusion rates.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Victoria Huynh, Kathryn Colborn, Shelby Smith, Levi N. Bonnell, Gretchen Ahrendt, Nicole Christian, Simon Kim, Dan D. Matlock, Clara Lee, Sarah E. Tevis
Summary: This study aimed to compare longitudinal patient-reported outcomes between breast cancer patients undergoing lumpectomy and mastectomy, finding that mastectomy patients experienced significantly greater decreases in breast satisfaction, psychosocial well-being, and sexual well-being over time compared with lumpectomy patients, with lumpectomy patients more likely to return to baseline scores at 3 and 6 months postoperatively. Understanding these differences can inform early intervention strategies to prevent long-term morbidities.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Multidisciplinary Sciences
Min Jung Kim, Soyoung Park, Ji Won Park, Jinsun Choi, Hyo Jun Kim, Han-Ki Lim, Seung-Bum Ryoo, Kyu Joo Park, Yosep Ji, Seung-Yong Jeong
Summary: This study investigated the correlation between gut microbiome and low anterior resection syndrome (LARS) symptoms. Stool samples from patients who underwent sphincter-preserving surgery (SPS) for rectal cancer were analyzed using 16S ribosomal RNA sequencing. The results showed that patients with frequency-dominant LARS symptoms had decreased gut microbiome diversity and lower levels of lactic acid-producing bacteria. In contrast, patients with incontinence-dominant LARS symptoms showed different microbial diversity and taxa. Overall, the study suggests a potential association between gut microbiome and LARS symptoms.
SCIENTIFIC REPORTS
(2023)
Article
Health Care Sciences & Services
Alin Nicola, Cristian Oancea, Paula Irina Barata, Mavrea Adelina, Tudor Mateescu, Diana Manolescu, Felix Bratosin, Roxana Manuela Fericean, Raja Akshay Pingilati, Cristian Paleru
Summary: This study investigates the correlation between the development of bronchiectasis after lung resection surgery and the health-related quality of life of patients. The study found that patients with bronchiectasis had poorer overall health status, increased respiratory symptoms, lower physical activity levels, lower quality of life scores, and experienced more severe anxiety symptoms. They also perceived higher levels of stress. Further research is needed to understand the contradictory correlations with stress and physical functioning.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Surgery
Rachel Xue Ning Lee, Maria Joao Cardoso, Kwok-Leung Cheung, Ruth M. Parks
Summary: The uptake of postmastectomy immediate breast reconstruction (PMIBR) in older women is significantly lower than in younger women, and there are definable (and some correctable) barriers to this trend.
BRITISH JOURNAL OF SURGERY
(2022)
Article
Environmental Sciences
Stana Pacaric, Zelimir Orkic, Marko Babic, Nikolina Farcic, Andrea Milostic-Srb, Robert Lovric, Ivana Barac, Stefica Miksic, Jasenka Vujanic, Tajana Turk, Zvjezdana Gvozdanovic, Dragica Pavlovic, Nika Srb, Ivana Pacaric
Summary: Mastectomy has a negative impact on the well-being of patients, and breast reconstruction is important for improving their quality of life. This study assessed the quality of life of patients who underwent immediate or delayed breast reconstruction after mastectomy, and found that immediate breast reconstruction improved physical health, while delayed reconstruction had a negative impact on mental health.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Marko Bergovec, Maria Smolle, Joerg Lindenmann, Melanie Fediuk, Andreas Leithner, Freyja-Maria Smolle-Juettner
Summary: This study retrospectively evaluated the outcomes of chest wall reconstruction after tumor resections, focusing on the use of titanium rib plates. The findings revealed a high rate of complications associated with the use of titanium plates, indicating the need for caution in selecting reconstruction methods.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Engineering, Biomedical
Claudius Steffen, Kay Sellenschloh, Magdalena Willsch, Ana Prates Soares, Michael M. Morlock, Max Heiland, Kilian Kreutzer, Gerd Huber, Carsten Rendenbach
Summary: This study aimed to examine whether patient-specific 3D-printed miniplates provide increased interosteotomy movement (IOM) and lower stiffness compared to reconstruction plates. The findings showed that miniplate fixation resulted in higher IOM in the distal gap, while there was no significant difference between the groups in the mesial gap. Surgeons should evaluate the primary use of 3D-printed miniplates in mandibular reconstruction due to advantages of intraoral plate removal and safe osteosynthesis.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)