Review
Medicine, General & Internal
Flavia M. Correa, Arn Migowski, Liz M. De Almeida, Marcelo A. Soares
Summary: This review discusses the current strategies in Brazil for screening, treatment, and prevention (HPV vaccination) against cervical cancer, highlighting the country's large public health system and the disparities in access to healthcare. It also explores the potential integration of newer technologies to eliminate cervical cancer.
FRONTIERS IN MEDICINE
(2022)
Review
Immunology
Asami Yagi, Yutaka Ueda, Mamoru Kakuda, Satoshi Nakagawa, Kosuke Hiramatsu, Ai Miyoshi, Eiji Kobayashi, Toshihiro Kimura, Megumi Kurosawa, Manako Yamaguchi, Sosuke Adachi, Risa Kudo, Masayuki Sekine, Yukio Suzuki, Akiko Sukegawa, Sayaka Ikeda, Etsuko Miyagi, Takayuki Enomoto, Tadashi Kimura
Summary: Despite the widely accepted national immunization program for HPV vaccination in Japan, the suspension of government recommendation due to adverse events led to a drastic drop in vaccination rates. Even with the introduction of a new vaccine, Japanese mothers remain hesitant, and it is crucial for educational and medical institutions to work harder in informing parents and children about the benefits of HPV vaccines.
Article
Engineering, Biomedical
Liming Zhang, Kun Wang, Yuheng Huang, Hui Zhang, Long Zhou, Ang Li, Yunyan Sun
Summary: A novel HPV nanovaccine combining nanotechnology and photodynamic therapy was constructed, which could effectively inhibit the progression of cervical cancer and was experimentally demonstrated in a mouse model.
Article
Oncology
Jacqueline M. Mix, Mona Saraiya, Trevor D. Thompson, Troy D. Querec, April Greek, Thomas C. Tucker, Edward S. Peters, Charles F. Lynch, Brenda Y. Hernandez, Glenn Copeland, Marc T. Goodman, Elizabeth R. Unger
Summary: The study compared HPV prevalence among high-grade cervical precancers and invasive cervical cancers before and after HPV vaccine availability. No significant reduction in vaccine-type prevalence was observed between the two studies, likely due to low HPV vaccination coverage among women in the postvaccine study. Monitoring HPV-type prevalence through population-based strategies remains important for evaluating the impact of the HPV vaccine.
Article
Public, Environmental & Occupational Health
Jiao Pei, Ting Shu, Chenyao Wu, Mandi Li, Minghan Xu, Min Jiang, Cairong Zhu
Summary: This study evaluated the early effect of the HPV vaccine on cervical cancer and found that the incidence of cervical cancer increased in age groups not receiving the vaccine while remained stable in vaccinated age groups.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Immunology
Folahanmi T. Akinsolu, Olunike Abodunrin, Ifeoluwa E. Adewole, Mobolaji Olagunju, Aisha O. Gambari, Dolapo O. Raji, Ifeoma E. Idigbe, Diana W. Njuguna, Abideen Salako, Oliver C. Ezechi
Summary: The lack of knowledge and willingness to pay for the HPV vaccine among women living with HIV in Nigeria highlights the importance of improving education and awareness to increase vaccine uptake.
Review
Chemistry, Multidisciplinary
Momeneh Ghanaat, Nasser Hashemi Goradel, Arash Arashkia, Nasim Ebrahimi, Sajjad Ghorghanlu, Ziba Veisi Malekshahi, Esmail Fattahi, Babak Negahdari, Hami Kaboosi
Summary: Persistent infection with high-risk types of HPV is known to be the leading cause of cervical cancer, leading to the development of various therapeutic approaches, with adenovirus vectors drawing attention due to their strong immunogenicity and safety.
ACTA PHARMACOLOGICA SINICA
(2021)
Article
Immunology
Miriam Gorgone, Andrea Squeri, Sara Cuffari, Vincenza La Fauci, Ioselita Giunta, Serena Calderone, Raffaele Squeri, Cristina Genovese
Summary: Cervical cancer screening adherence and HPV vaccination coverage in Italy are inadequate, likely due to communication and awareness issues, as well as lack of data from private tests. The introduction of HPV-DNA testing helps identify positive women with the most common genotypes associated with neoplastic lesions, as well as other genotypes worth investigating.
Article
Public, Environmental & Occupational Health
Juman Rezqalla, Mariam Alshatti, Amna Ibraheem, Danah Omar, Al-Failakawi Houda, Shamayel AlHaqqan, Sarah AlGhurair, Saeed Akhtar
Summary: This study found high levels of unawareness among female schoolteachers regarding the causal role of HPV in cervical cancer and the availability of HPV vaccine. Participants who were younger and had lower family incomes were more likely to be unaware of HPV's role in cervical cancer. Additionally, participants with a family or personal history of cervical cancer were less likely to be unaware of HPV's causal role.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Immunology
Mariko Taniguchi, Yutaka Ueda, Asami Yagi, Ai Miyoshi, Yusuke Tanaka, Ryoko Minekawa, Masayuki Endo, Takuji Tomimatsu, Kei Hirai, Tomio Nakayama, Tadashi Kimura
Summary: Women born between 1994 and 1999 with high HPV vaccination rates in Japan are now at the age for cervical cancer screening. Research showed that vaccinated women had better health awareness, while unvaccinated women were more influenced by fear of cancer. Tailored leaflets recommending screening increased rates slightly for both groups, indicating potential for improving cervical cancer control measures tailored to HPV vaccination status.
Article
Immunology
Supitcha Kamolratanakul, Punnee Pitisuttithum
Summary: Human papillomavirus (HPV) is the most common sexually transmitted infection, with 15 HPV types related to various cancers. HPV vaccines have been proven to be safe and highly effective in preventing HPV infections and associated cancers, especially among young women. The different types of HPV vaccines have shown similar efficacy in protecting against certain HPV types, with the nonavalent vaccine offering additional protection against more types. HPV vaccination has also been shown to provide herd protection and reduce the prevalence of HPV-related cancers.
Article
Medicine, General & Internal
Li Li, Mingyue Jiang, Tingyuan Li, Jian Yin, Ruimei Feng, Li Dong, Sufia Imam, Jianfeng Cui, Bin Liu, Xun Zhang, Qinjing Pan, Youlin Qiao, Wen Chen
Summary: This study investigated HPV genotype distribution among women aged 21 to 64 in Inner Mongolia and Shanxi Province in China who had not been vaccinated against HPV. The study found that HPV types 16, 52, 58, and 18 are common in the population and that HPV52 and 58 in the prophylactic HPV vaccine may enhance protection against cervical lesions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Microbiology
Xinyu Ren, Yubing Hao, Beike Wu, Xinhua Jia, Meili Niu, Kunbo Wang, Zhifang Li
Summary: This meta-analysis evaluated the efficacy of prophylactic HPV vaccines in preventing cervical cancer precursors and HPV persistent infection among Asian populations. The results showed that the vaccines were highly effective in reducing the risk of cervical intraepithelial neoplasia and HPV persistent infection. The study suggests that governments should prioritize the introduction and implementation of HPV vaccines in public health policies to increase awareness and uptake among Asian females.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Health Policy & Services
Nkwonta Chigozie, DeAnne K. Hilfinger Messiaa, Adegboyega Adebola, Tochukwu Ojiegbe
Summary: Cervical cancer is the second most common female cancer in Nigeria, and this study found that lack of male involvement and financial constraints are major obstacles to HPV vaccination and cervical screening. However, a majority of Nigerian men are willing to encourage and pay for their family members to receive these preventive services.
HEALTH PROMOTION INTERNATIONAL
(2022)
Review
Medicine, General & Internal
Rebecca B. Perkins, Nicolas Wentzensen, Richard S. Guido, Mark Schiffman
Summary: Each year in the US, about 100,000 people are treated for cervical precancer, 14,000 are diagnosed with cervical cancer, and 4,000 die from it. Almost all cervical cancers worldwide are caused by certain HPV genotypes. HPV vaccination at ages 9 to 12 can prevent over 90% of cervical precancers and cancers. Cervical cancer can be prevented through screening and treatment of cervical precancer in individuals with a cervix aged 21 to 65.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Education, Scientific Disciplines
Muktar H. Aliyu, Mahmoud U. Sani, Donna J. Ingles, Fatimah Tsiga-Ahmed, Baba M. Musa, Aimalohi A. Ahonkhai, Hamisu M. Salihu, Carolyn M. Audet, C. William Wester
Summary: There is a lack of structured mentoring programs targeting early-stage investigators in Africa, especially in areas with a high HIV burden. This study describes the findings from a workshop in Nigeria that aimed to build mentoring and leadership capacity in HIV and noncommunicable disease research for early-career physician scientists. The results showed that the participants identified building mentees' confidence and setting research goals as areas where they needed training the most. The workshop was rated favorably in multiple areas, and most participants stated that they learned something new and useful from each session.
JOURNAL OF CONTINUING EDUCATION IN THE HEALTH PROFESSIONS
(2022)
Article
Obstetrics & Gynecology
Zubairu Iliyasu, Hadiza S. Galadanci, Aisha Muhammad, Bilkisu Z. Iliyasu, Amina A. Umar, Muktar H. Aliyu
Summary: Most medical and allied health students in Kano, Nigeria, were willing to receive HPV vaccination despite having sub-optimal knowledge and low vaccine uptake. Factors such as gender, course of study, family history, and knowledge level of HPV were predictors of vaccine acceptance. These findings could help in the implementation and evaluation of HPV vaccine uptake as it expands across Africa.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Immunology
Zubairu Iliyasu, Aminatu A. Kwaku, Amina A. Umar, Fatimah Tsiga-Ahmed, Nafisa S. Nass, Hadiza M. Abdullahi, Taiwo G. Amole, Hamisu M. Salihu, Muktar H. Aliyu
Summary: This study aimed to assess the acceptability of COVID-19 vaccine and identify predictors and reasons for vaccine hesitancy among HIV patients in Kano, Nigeria. The results showed that vaccine acceptance was low among PLHIV and was associated with respondents' faith, risk perception, perception of the protective effects of antiretroviral treatment, concerns about COVID-19-HIV co-infection, and infertility-related rumors.
CURRENT HIV RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Zubairu Iliyasu, Hadiza S. Galadanci, Abubakar H. Musa, Bilkisu Z. Iliyasu, Nafisa S. Nass, Rayyan M. Garba, Abubakar M. Jibo, Sonia C. Okekenwa, Hamisu M. Salihu, Muktar H. Aliyu
Summary: The study found that willingness to self-test for HIV during pregnancy and postpartum was influenced by factors such as parity, employment status, and education level during pregnancy, while factors such as marital status, parity, employment status, and education level influenced willingness to self-test after delivery.
TROPICAL MEDICINE & INTERNATIONAL HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Zubairu Iliyasu, Muhammad R. Garba, Auwalu U. Gajida, Taiwo G. Amole, Amina A. Umar, Hadiza M. Abdullahi, Aminatu A. Kwaku, Hamisu M. Salihu, Muktar H. Aliyu
Summary: The study found that only 24.3% of hospital staff in a tertiary hospital in Kano, Nigeria were willing to accept the COVID-19 vaccine. Factors associated with lower acceptance included being female, nurses/midwives, not being tested for COVID-19, and perceiving oneself to be at low risk of COVID-19. On the other hand, vaccine acceptance was higher among more experienced workers who did not worry about vaccine efficacy, safety, side effects, or rumors.
PATHOGENS AND GLOBAL HEALTH
(2022)
Article
Medicine, General & Internal
Blake Angell, Olutobi Sanuade, Ifedayo M. O. Adetifa, Iruka N. Okeke, Aishatu Lawal Adamu, Muktar H. Aliyu, Emmanuel A. Ameh, Fatima Kyari, Muktar A. Gadanya, Diana A. Mabayoje, Adesola Yinka-Ogunleye, Tolu Oni, Rabiu Ibrahim Jalo, Fatimah I. Tsiga-Ahmed, Sarah L. Dalglish, Seye Abimbola, Tim Colbourn, Obinna Onwujekwe, Eme Theodora Owoaje, Gambo Aliyu, Sani H. Aliyu, Belinda Archibong, Alex Ezeh, Chikwe Ihekweazu, Zubairu Iliyasu, Stephen Obaro, Ebenezer Babatunde Obadare, Friday Okonofua, Muhammed Pate, Babatunde L. Salako, Fatima H. Zanna, Scott Glenn, Ally Walker, Maha Ezalarab, Mohsen Naghavi, Ibrahim Abubakar
Summary: Despite increased health expenditure in Nigeria, health outcomes remain poor. It is suggested that strengthening the health system and implementing targeted interventions could improve population health.
Review
Medicine, General & Internal
Ibrahim Abubakar, Sarah L. Dalglish, Blake Angell, Olutobi Sanuade, Seye Abimbola, Aishatu Lawal Adamu, Ifedayo M. O. Adetifa, Tim Colbourn, Afolabi Olaniyi Ogunlesi, Obinna Onwujekwe, Eme T. Owoaje, Iruka N. Okeke, Adebowale Adeyemo, Gambo Aliyu, Muktar H. Aliyu, Sani Hussaini Aliyu, Emmanuel A. Ameh, Belinda Archibong, Alex Ezeh, Muktar A. Gadanya, Chikwe Ihekweazu, Vivianne Ihekweazu, Zubairu Iliyasu, Aminatu Kwaku Chiroma, Diana A. Mabayoje, Mohammed Nasir Sambo, Stephen Obaro, Adesola Yinka-Ogunleye, Friday Okonofua, Tolu Oni, Olu Onyimadu, Muhammad Ali Pate, Babatunde L. Salako, Faisal Shuaib, Fatimah Tsiga-Ahmed, Fatima H. Zanna
Letter
Obstetrics & Gynecology
Zubairu Iliyasu, Jessica M. Perkins, Fatima I. Tsiga-Ahmed, Hadiza S. Galadanci, Abubakar M. Jibo, Taiwo G. Amole, Amina A. Umar, Hadiza M. Abdullahi, Aminatu A. Kwaku, Hamisu M. Salihu, Muktar H. Aliyu
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
(2022)
Article
Public, Environmental & Occupational Health
Tahir Dahiru, Zubairu Iliyasu, Muktar H. Aliyu
Summary: The burden of leprosy-related disability, stigma and social participation is high in Nigeria after completing treatment. Community-based rehabilitation is recommended to maintain self-care, reduce stigma and ensure social inclusion.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
(2022)
Article
Environmental Sciences
Zubairu Iliyasu, Rayyan M. Garba, Mansur A. Aliyu, Auwalu U. Gajida, Taiwo G. Amole, Amina A. Umar, Hadiza M. Abdullahi, Fatimah Tsiga-Ahmed, Aminatu A. Kwaku, Meira S. Kowalski, Hamisu M. Salihu, Muktar H. Aliyu
Summary: This study investigated the support for vaccine mandates and uptake among healthcare workers in a tertiary hospital in northern Nigeria. The findings revealed that less than half of the respondents supported the COVID-19 vaccine mandate, and a relatively low proportion had received the recommended doses of the vaccine. The study also identified factors such as profession, work experience, number of children, health status, and risk perception that predict support for the vaccine mandate and vaccine uptake.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Hamisu M. Salihu, Zenab Yusuf, Deepa Dongarwar, Sani H. Aliyu, Rafeek A. Yusuf, Muktar H. Aliyu, Gambo Aliyu
Summary: This study developed a dQAS tool to assess the validity of the NAIIS database and demonstrated the feasibility of remote internet-based collaboration for its development. The NAIIS database was found to be valid, reliable, and a valuable source of data.
JMIR FORMATIVE RESEARCH
(2022)
Article
Dermatology
Tahir Dahiru, Zubairu Iliyasu, Aliyu T. Mande, Anna T. Van't Noordende, Muktar H. Aliyu
Summary: The findings highlight the significance of community education and behavior change in transforming perceptions and behavior towards persons affected.
