A Mathematical Model of Tryptophan Metabolism via the Kynurenine Pathway Provides Insights into the Effects of Vitamin B-6 Deficiency, Tryptophan Loading, and Induction of Tryptophan 2,3-Dioxygenase on Tryptophan Metabolites

Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation

(2013) Ligi Paul et al.   NUTRITION REVIEWS

Tryptophan in Alcoholism Treatment I:  Kynurenine Metabolites Inhibit the Rat Liver Mitochondrial Low Km Aldehyde Dehydrogenase Activity, Elevate Blood Acetaldehyde Concentration and Induce Aversion to Alcohol

(2011) Abdulla A.-B. Badawy et al.   ALCOHOL AND ALCOHOLISM

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats

(2011) Nady Braidy et al.   FEBS Journal

Low Plasma Vitamin B-6 Status Affects Metabolism through the Kynurenine Pathway in Cardiovascular Patients with Systemic Inflammation

(2011) Øivind Midttun et al.   JOURNAL OF NUTRITION

The biological significance of substrate inhibition: A mechanism with diverse functions

(2010) Michael C. Reed et al.   BIOESSAYS

Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders

(2010) Gregory F. Oxenkrug   JOURNAL OF NEURAL TRANSMISSION

Impact of Tryptophan Metabolism on the Vulnerability to Alcohol-Related Blackouts and Violent Impulsive Behaviours

(2009) J. Vignau et al.   ALCOHOL AND ALCOHOLISM

Alterations of protein turnover underlying disuse atrophy in human skeletal muscle

(2009) S. M. Phillips et al.   JOURNAL OF APPLIED PHYSIOLOGY

Cooperative Binding of l-Trp to Human Tryptophan 2,3-Dioxygenase: Resonance Raman Spectroscopic Analysis

(2009) Eiko Fukumura et al.   JOURNAL OF BIOCHEMISTRY

A Mathematical Model Gives Insights into the Effects of Vitamin B-6 Deficiency on 1-Carbon and Glutathione Metabolism

(2009) H. Frederik Nijhout et al.   JOURNAL OF NUTRITION

Inhibitory Substrate Binding Site of Human Indoleamine 2,3-Dioxygenase

(2009) Changyuan Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased serum kynurenine/tryptophan ratio correlates with disease progression in lung cancer

(2009) Yuzo Suzuki et al.   LUNG CANCER

Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats

(2008) L. A. W. Jans et al.   AMINO ACIDS

Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II

(2008) Qian Han et al.   BIOSCIENCE REPORTS

Crystal Structure of theHomo sapiensKynureninase-3-Hydroxyhippuric Acid Inhibitor Complex: Insights into the Molecular Basis Of Kynureninase Substrate Specificity†

(2008) Santiago Lima et al.   JOURNAL OF MEDICINAL CHEMISTRY