4.6 Article

Total Zinc Absorption from a Diet Containing either Conventional Rice or Higher-Zinc Rice Does Not Differ among Bangladeshi Preschool Children

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JOURNAL OF NUTRITION
卷 143, 期 4, 页码 519-525

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OXFORD UNIV PRESS
DOI: 10.3945/jn.112.169169

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  1. HarvestPlus Challenge Program [8053]
  2. International Atomic Energy Agency [15197]

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Information is needed on zinc absorption from grain cultivars having higher zinc content. Total absorbed zinc (TAZ) from mixed diets containing high-zinc rice (HZnR), conventional rice (CR), or CR plus zinc fortificant (CR+Zn) was measured. Forty-two nonmalnourished preschool-aged children were enrolled in 1 of 2 groups. Using a crossover design, children in group A (n = 22) received for 1 d each a mixed diet containing 150 g CR or HZnR. Children in group B In = 20) received HZnR on 1 d and CR+Zn on the other day. Fractional zinc absorption (FZA) was measured during each dietary period by using a dual-isotope tracer ratio technique; TAZ was calculated as the product of zinc intake [total dietary zinc (TDZ)] and FZA. TDZ was 3.83, 4.83, and 6.03 mg/d when the children were fed the CR, HZnR, and CR+Zn containing diets, respectively. Mean FZA from the CR diet was greater than from the HZnR diet (25.1 vs. 20.1%, P < 0.001), and the mean FZA from the CR+Zn diet (18.8%) was less than from both the CR diet (P < 0.001) and the HZnR diet (P= 0.014). The mean TAZ was 0.96 +/- 0.16, 0.97 +/- 0.18, and 1.13 +/- 0.20 mg/d from the CR, HZnR and CR +Zn diets, respectively. TAZ was not different for the CR and HZnR diets (P= 0.99) but was significantly greater from the CR+Zn diet compared with the other 2 diets (P < 0.001). Rice cultivars with higher zinc and/or lower phytate content are needed to increase TAZ by young children consuming this amount of rice. J. Nutr. 143: 519-525, 2013.

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