期刊
JOURNAL OF NUTRITION
卷 142, 期 11, 页码 2010-2016出版社
AMER SOC NUTRITION-ASN
DOI: 10.3945/jn.112.163634
关键词
-
资金
- Bill and Melinda Gates Foundation
- NIH [T32HD046405]
Placental growth is a strong predictor of fetal growth, but little is known about maternal predictors of placental growth in malnourished populations. Our objective was to investigate in a prospective study the associations of maternal weight and body composition [total body water (TBW) estimated by bioelectrical impedance and fat and fat-free mass derived from upper arm fat and muscle areas (UAFA, UAMA)] and changes in these with placental and birth weights. Within a cluster-randomized trial of maternal micronutrient supplementation, a subsample of 350 women was measured 3 times across gestation. Longitudinal analysis was used to examine independent associations of similar to 10-wk measurements and similar to 10-20 wk and similar to 20-32 wk changes with birth outcomes. Weight, TBW, and UAMA, but not UAFA, at similar to 10 wk were each positively and independently associated with placental weight and birth weight (P < 0.05). Of the maternal similar to 10-20 wk changes in measurements, only TBW change and placental weight, and maternal weight and birth weight were positively associated (P < 0.05). Gains in weight, TBW, and UAMA from 20 to 32 wk were positively and UAFA gain was negatively associated with placental weight (P <= 0.01). Gains in weight and UAMA from 20 to 32 wk were positively associated with birth weight (P <= 0.01). Overall, higher maternal weight and measures of fat-free mass at similar to 10 wk gestation and gains from 20 to 32 wk are independently associated with higher placental and birth weight. J. Nutr. 142: 2010-2016, 2012.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据