The Niemann-Pick C1 Gene Is Downregulated in Livers of C57BL/6J Mice by Dietary Fatty Acids, but Not Dietary Cholesterol, through Feedback Inhibition of the SREBP Pathway

The Niemann-Pick C1 gene interacts with a high-fat diet and modifying genes to promote weight gain

(2011) David Jelinek et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance

(2010) D. Jelinek et al.   HUMAN MOLECULAR GENETICS

Polyunsaturated Fatty Acids Selectively Suppress Sterol Regulatory Element-binding Protein-1 through Proteolytic Processing and Autoloop Regulatory Circuit

(2010) Yoshinori Takeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis

(2010) J. N. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models

(2009) S. Nakav et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Decreased Npc1 Gene Dosage in Mice Is Associated With Weight Gain

(2009) David Jelinek et al.   Obesity

Cholesterol supply and SREBPs modulate transcription of the Niemann-Pick C-1 gene in steroidogenic tissues

(2008) Nicolas Gévry et al.   JOURNAL OF LIPID RESEARCH

The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts

(2008) William S. Garver et al.   JOURNAL OF LIPID RESEARCH