The eIF2 Kinase GCN2 Is Essential for the Murine Immune System to Adapt to Amino Acid Deprivation by Asparaginase1–3

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

(2010) Jiangbin Ye et al.   EMBO JOURNAL

Growing Rats Respond to a Sulfur Amino Acid–Deficient Diet by Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Heterotrimeric Complex and Induction of Adaptive Components of the Integrated Stress Response

(2010) Angelos K. Sikalidis et al.   JOURNAL OF NUTRITION

Blocking UV-Induced eIF2α Phosphorylation with Small Molecule Inhibitors of GCN2

(2009) Francis Robert et al.   Chemical Biology & Drug Design

GCN2 Protein Kinase Is Required to Activate Amino Acid Deprivation Responses in Mice Treated with the Anti-cancer Agent l-Asparaginase

(2009) Piyawan Bunpo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tryptophan Deprivation Induces Inhibitory Receptors ILT3 and ILT4 on Dendritic Cells Favoring the Induction of Human CD4+CD25+ Foxp3+ T Regulatory Cells

(2009) M. Brenk et al.   JOURNAL OF IMMUNOLOGY

Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response

(2009) M. S. Sundrud et al.   SCIENCE

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

CHR-2797: An Antiproliferative Aminopeptidase Inhibitor that Leads to Amino Acid Deprivation in Human Leukemic Cells

(2008) D. Krige et al.   CANCER RESEARCH

HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway

(2008) Jeong-In Lee et al.   PHYSIOLOGICAL GENOMICS