CCR2 Deficiency Impairs Macrophage Infiltration and Improves Cognitive Function after Traumatic Brain Injury

CCR2+Ly6Chi Inflammatory Monocyte Recruitment Exacerbates Acute Disability Following Intracerebral Hemorrhage

(2014) M. D. Hammond et al.   JOURNAL OF NEUROSCIENCE

Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases

(2013) Shambhunath Bose et al.   ARCHIVES OF PHARMACAL RESEARCH

Traumatic brain injury induces macrophage subsets in the brain

(2013) Christine L. Hsieh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Critical Role for Macrophages Near Axotomized Neuronal Cell Bodies in Stimulating Nerve Regeneration

(2013) J. P. Niemi et al.   JOURNAL OF NEUROSCIENCE

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

(2013) Douglas H. Smith et al.   Nature Reviews Neurology

The clinical spectrum of sport-related traumatic brain injury

(2013) Barry D. Jordan   Nature Reviews Neurology

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

(2012) S. Willenborg et al.   BLOOD

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

(2012) Alok Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

CCR2 Deficiency Prevents Neuronal Dysfunction and Cognitive Impairments Induced by Cranial Irradiation

(2012) K. Belarbi et al.   CANCER RESEARCH

Regulation of microglia development and homeostasis

(2012) Melanie Greter et al.   GLIA

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

(2012) Alok Kumar et al.   NEUROBIOLOGY OF AGING

Review: The long-term consequences of microglial activation following acute traumatic brain injury

(2012) C. Smith   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

(2012) Xuemei Jin et al.   PLoS One

Attenuated neurological deficit, cell death and lesion volume in Fas-mutant mice is associated with altered neuroinflammation following traumatic brain injury

(2011) Jenna M. Ziebell et al.   BRAIN RESEARCH

Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice

(2011) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Inhibitory control after traumatic brain injury in children

(2011) Katia J. Sinopoli et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood

(2011) M. Mizutani et al.   JOURNAL OF IMMUNOLOGY

Deficient CX3CR1 Signaling Promotes Recovery after Mouse Spinal Cord Injury by Limiting the Recruitment and Activation of Ly6Clo/iNOS+ Macrophages

(2011) D. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

CC Chemokine Receptor 2 Deficiency Aggravates Cognitive Impairments and Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) G. Naert et al.   JOURNAL OF NEUROSCIENCE

A mouse model of human repetitive mild traumatic brain injury

(2011) Michael J. Kane et al.   JOURNAL OF NEUROSCIENCE METHODS

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Neutrophil-dominant experimental autoimmune uveitis in CC-chemokine receptor 2 knockout mice

(2010) Koh-Hei Sonoda et al.   ACTA OPHTHALMOLOGICA

Alternatively activated myeloid (M2) cells enhance cognitive function in immune compromised mice

(2010) Noel C. Derecki et al.   BRAIN BEHAVIOR AND IMMUNITY

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Multiple roles for CCR2 during fracture healing

(2010) Z. Xing et al.   Disease Models & Mechanisms

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CCL2 modulates cytokine production in cultured mouse astrocytes

(2010) Bridgette D Semple et al.   Journal of Neuroinflammation

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Chemokines and chemokine receptors: an overview

(2009) Raffaella Bonecchi   Frontiers in Bioscience-Landmark

The phenotype of murine wound macrophages

(2009) Jean M. Daley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Chemokine Signaling and the Management of Neuropathic Pain

(2009) F. A. White et al.   MOLECULAR INTERVENTIONS

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE

Neuroprotection in traumatic brain injury

(2008) K.K. Jain   DRUG DISCOVERY TODAY

Chemokines and neuromodulation

(2008) Stéphane Mélik-Parsadaniantz et al.   JOURNAL OF NEUROIMMUNOLOGY

Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

(2008) Eric Lloyd et al.   Journal of Neuroinflammation

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA