Article
Emergency Medicine
Arjun Ganga, Eric J. Kim, Ermias S. Araia, Matthew Hagan, Belinda Shao, Konstantina Svokos, Petra M. Klinge, Deus J. Cielo, Jared S. Fridley, Ziya L. Gokaslan, Steven A. Toms, Patricia Zadnik Sullivan
Summary: The use of all-terrain vehicles (ATVs) poses significant risks, especially for children, who are more likely to suffer head injuries. This study aimed to analyze the annual incidence of ATV-related head injuries, classify injury types, and identify characteristics of the victims. The findings showed a high burden of ATV-related head injuries among children, with an increasing incidence in recent years.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Review
Clinical Neurology
Ron Gadot, Melissa A. LoPresti, David N. Smith, Lara Ouellette, Sandi Lam
Summary: Firearm-related traumatic brain injury (frTBI) is a significant cause of morbidity and mortality in pediatric populations. However, it is an understudied epidemiological entity and there is a need to increase understanding and promote interventions to reduce frTBI.
Article
Otorhinolaryngology
Elliott D. Kozin, Renata M. Knoll, Neil Bhattacharyya
Summary: There is a significant association between TBI and hearing loss in children, with those having TBI being 2.67 times more likely to have concurrent hearing complaints.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Family Studies
Katelyn M. Even, Kent P. Hymel, Veronica Armijo-Garcia, Matthew Musick, Kerri Weeks, Suzanne B. Haney, Mark Marinello, Bruce E. Herman, Terra N. Frazier, Christopher L. Carroll, Menglu Liang, Ming Wang
Summary: The study found that subcortical injury is strongly associated with the diagnosis of abusive head trauma (AHT), historical inaccuracies concerning abuse, traumatic extracranial injuries, and increased severity of illness.
CHILD ABUSE & NEGLECT
(2022)
Article
Surgery
Hannah Leblanc, Denise Danos, Rebecca Moreci, Lindsay Elliott, David C. Yu, Jessica A. Zagory
Summary: Traumatic injury is a major cause of mortality and morbidity in the United States, particularly among pediatric patients. Understanding the functional outcomes of pediatric trauma patients is crucial for planning appropriate rehabilitation care. This study aimed to describe the outcomes of pediatric and adolescent trauma patients and found that school-aged children had high rates of returning to school after various types of injuries. The length of hospital and rehabilitation stay was similar among different injury groups, and the majority of patients required durable medical equipment upon discharge. Patients with spinal cord injuries showed significant improvement in bladder function, while those with traumatic brain injuries showed improvement in memory and comprehension tasks.
JOURNAL OF SURGICAL RESEARCH
(2022)
Review
Pediatrics
Alessia Cicogna, Giulia Minca, Francesca Posocco, Federica Corno, Cecilia Basile, Liviana Da Dalt, Silvia Bressan
Summary: Minor blunt head trauma (MHT) is a common reason for children to visit the pediatric emergency department (ED). Although the incidence of clinically important traumatic brain injuries (ciTBIs) following MHT is low, many children undergo computed tomography (CT), putting them at risk of ionizing radiation. This narrative review examines the use of non-ionizing imaging modalities, including skull ultrasound, near-infrared spectroscopy (NIRS), and rapid magnetic resonance imaging (MRI), in the management of children with MHT. These imaging modalities may serve as adjuncts to the Pediatric Emergency Care Applied Research Network (PECARN) rule in helping clinicians make more accurate decisions regarding neuroimaging for children at high or intermediate PECARN risk of ciTBI.
FRONTIERS IN PEDIATRICS
(2022)
Article
Emergency Medicine
Benjamin Travers, Shanna Jones, Aveh Bastani, Michael Opsommer, Ali Beydoun, Patrick Karabon, David Donaldson
Summary: The L3TP protocol effectively and efficiently identifies intracranial hemorrhages in elderly patients with minor head trauma, resulting in shorter wait times and lengths of stay in the emergency department, without impacting health outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Clinical Neurology
Abhijith V. Matur, Laura B. Ngwenya, Charles J. Prestigiacomo
Summary: Motor vehicle collisions are a major cause of head injuries, but efforts to improve automobile design and promote helmet use have significantly reduced the number of serious head injuries. Neurosurgeons have played a crucial role in preventing head injuries and saving lives in MVCs through their recommendations and research efforts.
JOURNAL OF NEUROSURGERY
(2021)
Article
Pediatrics
Talia D. Baird, Michael R. Miller, Saoirse Cameron, Douglas D. Fraser, Janice A. Tijssen
Summary: A study on the mode of death for sTBI patients in a PCCU found that nearly half of the deaths were due to WLST, with a trend towards longer time to death in the physiologic death group. Few factors, such as higher PTT and lower albumin levels, were associated with the mode of death, both early and pre-death.
FRONTIERS IN PEDIATRICS
(2021)
Article
Surgery
Janet S. Lee, Abid D. Khan, Valerie Brockman, Thomas J. Schroeppel
Summary: The implementation of the GAP alert can reduce the utilization of trauma resources while providing timely diagnosis and treatment for elderly patients or those on anticoagulation medication with suspected TBI.
Article
Surgery
Kelli N. Patterson, Andrew Nordin, Tariku J. Beyene, Amanda Onwuka, Katherine Bergus, Kyle Z. Horvath, Eric A. Sribnick, Rajan K. Thakkar
Summary: The implementation of Level 1 Neuro (L1N) trauma activation is associated with shorter times to anesthesia and OR management for severe TBI patients. Compared to other activation levels, L1N trauma patients had shorter times for both anesthesia and OR management.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Clinical Neurology
Patrick D. Kelly, Pious D. Patel, Aaron M. Yengo-Kahn, Daniel Wolfson, Fakhry Dawoud, Ranbir Ahluwalia, Oscar D. Guillamondegui, Christopher M. Bonfield
Summary: This study assessed the accuracy of the Baylor score among patients who survived the acute phase of hospitalization for gunshot wounds to the head, finding that while the score accurately predicted mortality and functional outcome, it tended to overestimate mortality and underestimate good functional outcome.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
M. Jensen Kracht, Amy Stein, Christine Knoll, Priscila Badia Alonso, Esteban Gomez, Maa-Ohui Quarmyne, Sanjay Shah, Joanna Gendreau
Summary: This study aimed to investigate the prevalence and clinical characteristics of intracranial hemorrhage (ICH) in hemophilia patients presenting to the emergency department (ED) with head trauma. A retrospective chart review was conducted, and the prevalence of ICH was found to be 4%. The study also proposed a new algorithm to aid clinicians in determining the need for CT scan in pediatric hemophilia patients with head trauma presenting to the ED.
PEDIATRIC BLOOD & CANCER
(2022)
Article
Surgery
Cassie A. Barton, Heath J. Oetken, Nicolas L. Hall, Andrew J. Webb, Heather E. Hoops, Martin Schreiber
Summary: After demonstrating bleeding stability on the initial interval scan, tICH patients rarely experience expansion. Patients may be considered for discharge from the ICU when there is no progression on the initial interval scan.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Critical Care Medicine
Delbrynth P. Mitchao, Meghan Lewis, Dominik Jakob, Elizabeth R. Benjamin, Demetrios Demetriades
Summary: The study reveals a low rate of helmet use among skateboard injury patients, and highlights the protective effects of skate parks and helmet use against severe traumatic brain injury. Older children and males are more prone to severe TBI after skateboard-related injuries, indicating the need for targeted preventive education and legislation.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Article
Clinical Neurology
Palma Ciaramitaro, Luca Massimi, Alessandro Bertuccio, Alessandra Solari, Mariangela Farinotti, Paola Peretta, Veronica Saletti, Luisa Chiapparini, Andrea Barbanera, Diego Garbossa, Laura Valentini
Summary: This study aimed to reach a consensus among international experts on controversial issues in the diagnosis and treatment of Chiari 1 malformation and syringomyelia in adults. Through a multidisciplinary panel, a Delphi process, and face-to-face discussions, a consensus was reached on 57 out of 63 statements related to the conditions. The consensus document, consisting of 63 statements, was the result of expert discussion and serves as a guide for clinicians and researchers following adults with Chiari and syringomyelia.
NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Luca Massimi, Paola Peretta, Alessandra Erbetta, Alessandra Solari, Mariangela Farinotti, Palma Ciaramitaro, Veronica Saletti, Massimo Caldarelli, Alexandre Casagrande Canheu, Carlo Celada, Luisa Chiapparini, Daniela Chieffo, Giuseppe Cinalli, Federico Di Rocco, Marika Furlanetto, Flavio Giordano, George Jallo, Syril James, Paola Lanteri, Christian Lemarchand, Martina Messing-Juenger, Cecilia Parazzini, Giovanna Paternoster, Gianluca Piatelli, Maria A. Poca, Prab Prabahkar, Federica Ricci, Andrea Righini, Francesco Sala, Juan Sahuquillo, Marcus Stoodley, Giuseppe Talamonti, Dominic Thompson, Fabio Triulzi, Mino Zucchelli, Laura Valentini
Summary: Through the Delphi study, an international panel of experts reached consensus on the diagnosis and treatment of CM1 in children, with a total of 58 statements covering four main sections including Definition and Classification, Planning, Surgery, and Isolated Syringomyelia. The article emphasizes the need for establishing an international network and registry, as well as promoting collaborative studies to enhance the evidence base and optimize long-term care for this patient population.
NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Stefania Galimberti, Francesca Graziano, Andrew I. R. Maas, Giulia Isernia, Fiona Lecky, Sonia Jain, Xiaoying Sun, Raquel C. Gardner, Sabrina R. Taylor, Amy J. Markowitz, Geoffrey Manley, Maria Grazia Valsecchi, Giuseppe Bellelli, Giuseppe Citerio
Summary: Frailty is associated with outcomes in patients with traumatic brain injury, and a frailty index has been developed to predict 6-month outcomes.
Article
Critical Care Medicine
Iris E. Ceyisakar, Jilske A. Huijben, Andrew I. R. Maas, Hester F. Lingsma, Nikki van Leeuwen
Summary: This study aimed to investigate if European neurotrauma centers can be clustered based on their treatment preference in different domains of traumatic brain injury care in the intensive care unit (ICU). Provider profiles from 66 centers in 20 different countries in Europe and Israel were analyzed, revealing correlations within and between treatment domains, but hospitals could not be grouped based on their treatment preference.
NEUROCRITICAL CARE
(2022)
Article
Critical Care Medicine
Giovanna Maria Dimitri, Erta Beqiri, Michal M. Placek, Marek Czosnyka, Nino Stocchetti, Ari Ercole, Peter Smielewski, Pietro Lio
Summary: This study investigated simultaneous increases in HR and ICP in TBI patients and their relationship with mortality. Novel brain-heart interaction indicators were introduced, showing a negative correlation with mortality, suggesting a healthy brain-cardiovascular interaction plays a role in TBI.
NEUROCRITICAL CARE
(2022)
Article
Critical Care Medicine
Julia K. Boehm, Victoria Schaeben, Nadine Schaefer, Helge Gueting, Rolf Lefering, Sophie Thorn, Herbert Schoechl, Johannes Zipperle, Oliver Grottke, Rolf Rossaint, Simon Stanworth, Nicola Curry, Marc Maegele
Summary: Trauma-induced coagulopathy in traumatic brain injury (TBI) is associated with high rates of complications and mortality. In this study, patients with TBI were assessed for coagulation profiles and those with elevated INR values had higher mortality rates and worse outcomes. Additionally, levels of coagulation factors and thrombin generation varied between patients with different INR values.
NEUROCRITICAL CARE
(2022)
Article
Clinical Neurology
Nina M. Rzechorzek, Michael J. Thrippleton, Francesca M. Chappell, Grant Mair, Ari Ercole, Manuel Cabeleira, Jonathan Rhodes, Ian Marshall, John S. O'Neill
Summary: Temperature-based treatment after brain injury is controversial due to the undefined 'normal' human brain temperature. A study shows that human brain temperature exceeds body temperature by 2-3 degrees C and varies by age, sex, brain region, and time. Loss of daily brain temperature rhythm predicts death after traumatic brain injury. This study aimed to determine the clinical relevance of brain temperature in patients and analyzed the variations in healthy adults' brain temperature.
Article
Clinical Neurology
Angelos G. Kolias, Hadie Adams, Ivan S. Timofeev, Elizabeth A. Corteen, Iftakher Hossain, Marek Czosnyka, Jake Timothy, Ian Anderson, Diederik O. Bulters, Antonio Belli, C. Andrew Eynon, John Wadley, A. David Mendelow, Patrick M. Mitchell, Mark H. Wilson, Giles Critchley, Juan Sahuquillo, Andreas Unterberg, Jussi P. Posti, Franco Servadei, Graham M. Teasdale, John D. Pickard, David K. Menon, Gordon D. Murray, Peter J. Kirkpatrick, Peter J. Hutchinson
Summary: Through a 24-month follow-up observation of patients with traumatic intracranial hypertension, it was found that surgical treatment can continuously reduce the mortality rate and increase the incidence of vegetative state, severe disability, and moderate disability. Compared with the medical treatment group, patients in the surgical group have a higher probability of improvement in their condition.
Article
Multidisciplinary Sciences
Fabian Bockhop, Marina Zeldovich, Katrin Cunitz, Dominique Van Praag, Marjolein van der Vlegel, Tim Beissbarth, York Hagmayer, Nicole von Steinbuechel
Summary: The study examines the factorial validity and cross-linguistic equivalence of the PCL-5 in individuals with TBI. The results demonstrate the comparability of PCL-5 symptom scores between different languages, supporting the validity of the DSM-5 conceptualization of PTSD.
SCIENTIFIC REPORTS
(2022)
Review
Immunology
Paula Mc Kenna, Lindsay A. Broadfield, Annik Willems, Serge Masyn, Theresa Pattery, Ruxandra Draghia-Akli
Summary: Digital health tools can greatly benefit large-scale vaccination campaigns, especially in low- and middle-income countries. Selecting the right tool for the existing digital landscape can be challenging.
EXPERT REVIEW OF VACCINES
(2023)
Correction
Critical Care Medicine
Emanuele Rezoagli, Matteo Petrosino, Paola Rebora, David Menon, Stefania Mondello, D. James Cooper, Andrew I. R. Maas, Eveline J. A. Wiegers, Stefania Galimberti, Giuseppe Citerio, Cecilia Ackerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Gerard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Ronny Beer, Bo-Michael Bellander, Habib Benali, Maurizio Berardino, Luigi Beretta, Erta Beqiri, Morten Blaabjerg, Stine Borgen Lund, Camilla Brorsson, Andras M. Buki, Manuel Cabeleira, Alessio Caccioppola, Emiliana Calappi, Maria Rosa Calvi, Peter Cameron, Guillermo Carbayo Lozano, Marco Carbonara, Ana D. Castano-Leon, Simona Cavallo, Giorgio Chevallard, Arturo Chieregato, Hans Clusmann, Mark Steven Coburn, Jonathan Coles, Jamie Cooper, Marta Correia, Endre Czeiter, Marek Czosnyka, Claire Dahyot-Fizelier, Paul Dark, Veronique Keyser, Vincent Degos, Francesco Della Corte, Hugo Boogert, Bart Depreitere, Dula Dilvesi, Abhishek Dixit, Jens Dreier, Guy-Loup Duliere, Ari Ercole, Erzsebet Ezer, Martin Fabricius, Kelly Foks, Shirin A. Frisvold, Alex Furmanov, Damien Galanaud, Dashiell Gantner, Alexandre Ghuysen, Lelde Giga, Jagos Golubovic, Pedro Gomez, Benjamin J. Gravesteijn, Francesca Grossi, Deepak Gupta, Iain Haitsma, Raimund G. Helbok, Eirik Helseth, Jilske Huijben, Peter Hutchinson, Stefan Jankowski, Faye Johnson, Mladen Karan, Angelos Kolias, Daniel Kondziella, Evgenios Kornaropoulos, Lars-Owe Koskinen, Noemi Kovacs, Ana Kowark, Alfonso Lagares, Steven Laureys, Aurelie Lejeune, Fiona Lecky, Didier Ledoux, Roger Lightfoot, Hester Lingsma, Alex Manara, Hugues Marechal, Costanza Martino, Julia Mattern, Catherine McMahon, Tomas Menovsky, Benoit Misset, Visakh Muraleedharan, Lynnette Murray, Ancuta Negru, David Nelson, Virginia Newcombe, Jozsef Nyiradi, Fabrizio Ortolano, Jean-Francois Payen, Vincent Perlbarg, Paolo P. Persona, Wilco Peul, Anna Piippo-Karjalainen, Horia Ples, Inigo Pomposo, Jussi Posti, Louis Puybasset, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Sophie Richter, Saulius Rocka, Cecilie Roe, Olav Roise, Jeffrey Rosenfeld, Christina Rosenlund, Guy Rosenthal, Rolf Rossaint, Sandra Rossi, Juan Sahuquillo, Oliver Sakowitz, Renan Sanchez-Porras, Oddrun Sandrod, Kari Schirmer-Mikalsen, Rico Frederik W. Schou, Charlie Sewalt, Peter Smielewski, Abayomi Sorinola, Emmanuel Stamatakis, Ewout Steyerberg, Nino Stocchetti, Nina Sundstroem, Riikka Takala, Viktoria Tamas, Tomas Tamosuitis, Olli Tenovuo, Matt Thomas, Dick Tibboel, Christos Tolias, Tony Trapani, Cristina Maria Tudora, Andreas Unterberg, Peter Vajkoczy, Egils A. Valeinis, Shirley Vallance, Zoltan Vamos, Gregory Steen, T. J. M. van Dijck Jeroen, Thomas Essen, Roel Wijk, Alessia Vargiolu, Emmanuel Vega, Anne Vik, Rimantas Vilcinis, Victor Volovici, Peter Vulekovic, Eveline A. Wiegers, Guy Williams, Stefan Winzeck, Stefan Wolf, Alexander Younsi, Frederick Zeiler, Agate Ziverte, Tommaso V. Zoerle, Russel Gruen, Lynette Murray, Dinesh Varma, Christopher MacIsaac, Andrea Jordan
INTENSIVE CARE MEDICINE
(2023)
Review
Medicine, General & Internal
Juan Sahuquillo, Dulce Moncho, Alex Ferre, Diego Lopez-Bermeo, Aasma Sahuquillo-Muxi, Maria A. Poca
Summary: This review examines different classification approaches for Chiari malformations and proposes a simplified scheme to differentiate between various types of tonsillar herniations. It also explores the most appropriate terminology for acquired herniation of cerebellar tonsils and other secondary Chiari-like malformations. This paper contributes to the ongoing discussion by offering insights into the evolving understanding of Chiari malformations and proposing a simplified classification and terminology system for diagnosis and management.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
M. Angeles Sanchez Roldan, Dulce Moncho, Kimia Rahnama, Daniela Santa-Cruz, Elena Lainez, Daniel Baiget, Ivette Chocron, Dario Gandara, Agustin Bescos, Juan Sahuquillo, Maria A. Poca
Summary: This study retrospectively reviewed the neurophysiological data of syringomyelia surgery and found that multimodal IONM is feasible and reliable in preventing iatrogenic spinal cord injury.
JOURNAL OF CLINICAL MEDICINE
(2023)
Meeting Abstract
Endocrinology & Metabolism
S. Tagliabue, M. Kacprzak, I. Serra Mochales, A. Re-Perez, J. Baena, J. Fischer, F. Maruccia, M. Poca, J. Sahuquillo, T. Durduran
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Article
Clinical Neurology
Victor Volovici, Dana Pisica, Benjamin Y. Gravesteijn, Clemens M. F. Dirven, Ewout W. Steyerberg, Ari Ercole, Nino Stocchetti, David Nelson, David K. Menon, Giuseppe Citerio, Mathieu van der Jagt, Andrew I. R. Maas, Iain K. Haitsma, Hester F. Lingsma
Summary: Comparing outcomes between EVD-driven and IP monitor-driven treatment of intracranial hypertension in TBI patients, there were no major differences in functional outcomes. However, patients receiving EVD treatment had a longer length of ICU stay and a higher prevalence of complications.
ACTA NEUROCHIRURGICA
(2022)