Review
Clinical Neurology
Ibrahem Albalkhi, Sarah Garatli, Baraa Helal, Tariq Saleh, Abdullah Husain AlRamadan, Benjamin Curtis Warf
Summary: Approaches to the treatment of infant hydrocephalus vary, and traditional shunting procedures have disadvantages. The combined use of CPC and ETV has been increasingly employed as an alternative to shunt dependency. A systematic review and meta-analysis were conducted to explore the morbidity and success rates of ETV/CPC for infant hydrocephalus.
NEUROSURGICAL REVIEW
(2023)
Article
Clinical Neurology
Benjamin C. Warf, Daniel S. Weber, Emily L. Day, Coleman P. Riordan, Steven J. Staffa, Lissa C. Baird, Katie P. Fehnel, Scellig S. D. Stone
Summary: This study compared the outcomes of endoscopic third ventriculostomy (ETV) with choroid plexus cauterization (CPC) and ventriculo-peritoneal shunt (VPS) placement in infants under 12 months old with hydrocephalus. The authors found that ETV/CPC was more successful in avoiding reoperation and achieving long-term shunt freedom in infants older than 2.5 months without prior cerebrospinal fluid (CSF) diversion. However, the success rate of ETV/CPC was lower in infants under 2.5 months old with prior CSF diversion.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2023)
Review
Clinical Neurology
Ian C. Coulter, Michael C. Dewan, Jignesh Tailor, George M. Ibrahim, Abhaya Kulkarni
Summary: Choroid plexus cauterization (CPC) combined with endoscopic third ventriculostomy (ETV) has proven to be an effective treatment for hydrocephalus, especially in infants, reducing the need for shunt dependency. In recent years, there has been a growing popularity of this combination surgery worldwide, as increasing evidence highlights its efficacy in comparison to traditional shunting procedures.
CHILDS NERVOUS SYSTEM
(2021)
Article
Clinical Neurology
Randaline R. Barnett, Allie L. Harbert, Hengameh B. Pajer, Angela Wabulya, Valerie L. Jewells, Scott W. Elton, Carolyn S. Quinsey
Summary: This study retrospectively analyzed 37 pediatric patients who underwent ETV/CPC for hydrocephalus and found that 24% of them developed clinical seizures within 24 hours after surgery. Among these patients, 80% of the postoperative electrographic seizures might be associated with the hemisphere through which the endoscope was introduced. The use of prophylactic levetiracetam was shown to effectively reduce the incidence of postoperative seizures.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Article
Clinical Neurology
Omar Abdel Aleem Ragab, Hussein Fathalla, Walid El Halaby, Wael Maher, Mohamed Hafez, Ahmed Zohdi
Summary: This study reviewed a series of spontaneous third ventriculostomy (STV) cases and found that STV is a rare occurrence in cases of chronic obstructive hydrocephalus, which can arrest active hydrocephalus. The results of this study suggest that neurosurgeons should consider the possibility of STV when performing cine phase-contrast magnetic resonance imaging (PC-MRI) in patients with chronic obstructive hydrocephalus, rather than solely relying on aqueductal stenosis to determine the need for cerebrospinal fluid diversion.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Anastasia Arynchyna-Smith, Curtis J. Rozzelle, Hailey Jensen, Ron W. Reeder, Abhaya Kulkarni, Ian F. Pollack, John C. Wellons, Robert P. Naftel, Eric M. Jackson, William E. Whitehead, Jonathan A. Pindrik, David D. Limbrick, Patrick J. McDonald, Mandeep S. Tamber, Brent R. O'Neill, Jason S. Hauptman, Mark D. Krieger, Jason Chu, Tamara D. Simon, Jay Riva-Cambrin, John R. W. Kestle, Brandon G. Rocque
Summary: ETV revision had a significantly lower 1-year success rate than initial ETV+CPC and VPS placement after ETV+CPC. Complication rates were similar for all studied procedures. Younger age, but not time since initial ETV+CPC, was a risk factor for ETV revision failure.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2021)
Review
Neurosciences
Ronnie E. Baticulon, Michael C. Dewan
Summary: Pediatric hydrocephalus is a significant global burden, especially in low- and middle-income countries, and is commonly treated with ventriculoperitoneal shunting. However, the combined use of ETV and CPC has shown promise in allowing patients to live without a shunt. Success of ETV+CPC is highest in infants older than 1 month with noninfectious hydrocephalus, while failure is commonly seen within 3-6 months post-surgery in certain patient populations. Long-term studies are needed to further evaluate functional and neurocognitive outcomes.
Article
Clinical Neurology
Bamidele Oludele Adebayo, Okezie Obasi Kanu, Olufemi B. Bankole, Omotayo Abimbola Ojo, Babatunde Adetunmbi, Eghosa Morgan
Summary: This study compared the success rate and morbidity of ETV + CPC and VPS as the primary treatment for hydrocephalus in myelomeningocele patients. The results showed that ETV + CPC had similar success rate as VPS at 6 months follow-up, but with lower morbidity. ETV + CPC may be considered a viable alternative for treating myelomeningocele patients with hydrocephalus.
OPERATIVE NEUROSURGERY
(2021)
Article
Clinical Neurology
Bamidele Oludele Adebayo, Okezie Obasi Kanu, Olufemi B. Bankole, Omotayo Abimbola Ojo, Babatunde Adetunmbi, Eghosa Morgan
Summary: Myelomeningocele is often accompanied by hydrocephalus, which is commonly treated with ventriculoperitoneal shunt (VPS). However, endoscopic third ventriculostomy (ETV) with choroid plexus cauterization (CPC) is emerging as a viable alternative with similar success rates and lower morbidity.
OPERATIVE NEUROSURGERY
(2021)
Article
Clinical Neurology
H. Westley Phillips, Jia-Shu Chen, Alexander M. Tucker, Kevin Ding, Alon Kashanian, Yasunori Nagahama, Gary W. Mathern, Alexander G. Weil, Aria Fallah
Summary: To prevent posthemispherectomy hydrocephalus (PHH), open choroid plexus cauterization (CPC) was incorporated into the procedure. Patients who underwent CPC had a lower rate of cerebrospinal fluid (CSF) shunting for PHH and similar rates of seizure freedom and postoperative complications. The incorporation of routine CPC effectively prevented PHH without causing additional complications.
Article
Clinical Neurology
Maya Kono, Kyoji Tsuda, Mami Yamashita, Satoshi Ihara
Summary: The study explored the effectiveness of repeat ETV combined with choroid plexus cauterization for ETV failure, and found that all repeat ETVs were successful.
CHILDS NERVOUS SYSTEM
(2022)
Article
Clinical Neurology
Yuki Munekata, Taku Sugiyama, Yuki Ueda, Makoto Mizushima, Hiroaki Motegi, Miki Fujimura
Summary: This article presents a rare case of late-onset obstructive hydrocephalus associated with occipital encephalocele. The patient did not show any signs of hydrocephalus until the age of 7, but later developed worsened gait and enlarged ventricles. Endoscopic third ventriculostomy provided symptom relief.
CHILDS NERVOUS SYSTEM
(2022)
Review
Clinical Neurology
Syawaluddin Hilman, Eppy Buchori Aristiady, Leni Santiana, Dian Komala Dewi, Harry Galuh Nugraha
Summary: Patients with TVFB have a higher success rate in ETV surgery, and TVFB has a significant impact on surgical success.
WORLD NEUROSURGERY
(2022)
Review
Clinical Neurology
David Ben-Israel, Jennifer A. Mann, Michael M. H. Yang, Albert M. Isaacs, Magalie Cadieux, Nicholas Sader, Sandeep Muram, Abdulrahman Albakr, Branavan Manoranjan, Richard W. Yu, Benjamin Beland, Mark G. Hamilton, Eldon Spackman, Paul E. Ronksley, Jay Riva-Cambrin
Summary: This systematic review and meta-analysis provides a comprehensive overview of the ETV+CPC failure rate, showing a significant difference in failure rates based on geographic income levels. It also presents the first reported pooled estimates for ETV+CPC perioperative mortality, intraoperative abandonment, and CSF infection risks. The low quality of evidence highlights the need for further research to improve understanding of critical clinical outcomes and patient selection for ETV+CPC.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2021)
Article
Clinical Neurology
Matteo Martinoni, Giovanni Miccoli, Luca Albini Riccioli, Francesca Santoro, Giacomo Bertolini, Corrado Zenesini, Diego Mazzatenta, Alfredo Conti, Luigi Maria Cavallo, Giorgio Palandri
Summary: The aim of this study was to evaluate the neurocognitive outcome in patients with late-onset idiopathic aqueductal stenosis (LIAS) who underwent endoscopic third ventriculostomy (ETV). The results showed that ETV is a safe and effective surgical procedure for the treatment of LIAS, with improvements in neurological and neurocognitive functions observed postoperatively.
FRONTIERS IN NEUROLOGY
(2022)