Article
Surgery
Sven Zittel, Oliver Ristow, Julius Moratin, Thomas Rueckschloss, Jurgen Hoffmann, Ahmed El Damaty, Christian Freudlsperger, Michael Engel
Summary: In the surgical treatment of metopic synostosis, the use of resorbable materials for fixation is common practice. This study aimed to investigate whether there are limitations to the endocortical positioning of resorbable plates. The results showed that the risk level of using endocortical resorbable plates positioned on the inner surface of the bone is low, and there were no detected disadvantages from an aesthetic point of view.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Article
Surgery
Sarah N. Chiang, Gary B. Skolnick, Sybill D. Naidoo, Matthew D. Smyth, Kamlesh B. Patel
Summary: This study examines the outcomes of endoscopic craniosynostosis repair in syndromic patients. Syndromic craniosynostosis was associated with a higher need for secondary procedures and transfusions. The degree of patient-reported stigma was higher in syndromic patients, but cognitive function did not differ significantly.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Dentistry, Oral Surgery & Medicine
L. Chandler, K. E. Park, O. Allam, M. A. Mozaffari, S. Khetpal, J. Smetona, N. Pourtaheri, X. Lu, J. A. Persing, M. Alperovich
Summary: This study conducted a craniomorphometric analysis of patients undergoing surgery for metopic synostosis, finding that the frontal angle and aEBF were the most accurate measures of severity in this condition.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Surgery
Laura Culshaw, Katie Piggott, Helen Care, Louise Dalton, Susie Denly, Jo Horton, Patrick Kennedy-Williams, Molly Pinckston, Natasha Rooney, Hannah Thornhill, Christopher Parks, Anna Kearney
Summary: The Craniofacial Collaboration UK (CC-UK) is a joint organization established across the 4 highly specialized craniofacial centers in the UK since 2015. Its aim is to address limitations in developmental craniofacial research and utilize robust clinical data from a homogenous sample of children. This paper presents the third wave of findings from CC-UK, focusing on developmental and behavioral parent-report measures. The results indicate similar patterns to previous CC-UK work, with most children falling within the population normative means. However, children with metopic synostosis (MS) show statistically significant difficulties in various developmental and behavioral domains, particularly in prosocial skills and peer difficulties.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Editorial Material
Surgery
Seija Maniskas, Ludmila Chandler, Karl Bruckman, Navid Pourtaheri, Michael DiLuna, Derek M. Steinbacher
Summary: Metopic craniosynostosis leads to trigonocephaly, with distinct features including a triangular forehead with metopic ridge, bitemporal pinching, and narrow-set eyes with recessed lateral orbital rims. Surgical management, which may involve open expansion and vault remodeling, is controversial but aims to improve neurocognitive and aesthetic outcomes. This article and video illustrate the diagnosis and treatment of metopic craniosynostosis, showcasing the senior author's open approach, three-dimensional virtual surgical planning, and technical steps.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Clinical Neurology
Kaamya Varagur, Gary B. Skolnick, Sybill D. Naidoo, Matthew D. Smyth, Kamlesh B. Patel
Summary: This study examines facial asymmetry, desire for revision, and patient-reported outcomes at school age in children who received either endoscopic strip craniectomy with helmet therapy or fronto-orbital advancement (open repair) for unilateral coronal synostosis. The results show that children who underwent open or endoscopic repair have comparable facial symmetry at school age, but midface depth remains highly asymmetrical in both groups. Forehead asymmetry at school age correlates with parent-and physician-reported desire for revision.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Article
Clinical Neurology
Ahmed Elawadly, Luke Smith, Alessandro Borghi, Khaled Abdelaziz, Adikarige Haritha Dulanka Silva, David J. Dunaway, Noor Ul Owase Jeelani, Juling Ong, Greg James
Summary: Endoscopic strip craniectomy with postoperative helmet orthosis therapy (ESCH) is a less invasive alternative for treating trigonocephaly, and monitoring morphological changes using 3D stereophotogrammetry (3DSPG) is effective and avoids the use of ionizing radiation and anesthesia. This method can be useful for evaluating changes in head shape after ESCH treatment.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2021)
Article
Clinical Neurology
Nathan K. Leclair, William A. Lambert, Joshua Knopf, Petronella Stoltz, David S. Hersh, Jonathan E. Martin, Markus J. Bookland
Summary: This study compared the postoperative skull morphology changes in patients with sagittal craniosynostosis and metopic craniosynostosis. The results showed that patients with metopic craniosynostosis had a prolonged rate of change compared to patients with sagittal craniosynostosis, indicating that metopic craniosynostosis patients may require longer treatment and follow-up.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Article
Clinical Neurology
Qing Yan, Junping He, Zhe Gao, Dezhi Qiu, Lei Zheng, Xianli Zhang, Gang Wang
Summary: The study evaluated the efficacy of fronto-orbit reconstruction surgery on pediatric metopic synostosis using 3D reconstruction in Chinese population. Following the surgery, significant improvements were observed in frontal volume, intracranial volume, and ECA, with no obvious complications.
CHILDS NERVOUS SYSTEM
(2021)
Article
Engineering, Multidisciplinary
Qian Liu, Xueliang Peng, Xiaojia Liu, Xiaohui Mou, Yayuan Guo, Lihua Yang, Yufei Chen, Yaying Zhou, Zhuoya Shi, Zhilu Yang, Zhuoyue Chen
Summary: BMPs, members of the TGF-8 superfamily, have been extensively studied for their osteoinductive ability and multiple functions. Current research focuses on BMP delivery systems to achieve local administration and delay degradation. Researchers have combined BMPs with other growth factors to enhance their effect during osteoinduction. This paper reviews the progress in BMP research, including structure and function, binding to various materials, cells, and growth factors. It also summarizes the applications of BMPs in bone defect repair and proposes suggestions for improving their clinical application.
COMPOSITES PART B-ENGINEERING
(2023)
Article
Dentistry, Oral Surgery & Medicine
X. Lu, A. J. Forte, A. Wilson, K. E. Park, O. Allam, M. Alperovich, D. M. Steinbacher, C. Tonello, N. Alonso, J. A. Persing
Summary: This study found that airway compromise in Crouzon syndrome patients is related to different types of cranial vault suture synostosis. Patients with type III showed the most severe restriction in both nasal and pharyngeal airways during infancy, while those with type II had normal nasopharyngeal airway volume.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Clinical Neurology
Tiffany Berrington, Matthias Schulz, Hans Delye, Greg James
Summary: This study provides a snapshot of current standards of care for craniosynostosis across high-volume centers of the European Reference Networks. The results can be used to analyze and guide the development of management guidelines for patients with both single-suture and multisutural craniosynostosis.
WORLD NEUROSURGERY
(2022)
Article
Surgery
Irene M. J. Mathijssen, Eppo B. Wolvius, Jochem K. H. Spoor, Marie-Lise C. van Veelen, Sarah L. Versnel
Summary: This study aims to identify certain types of craniosynostosis and surgical procedures that are more likely to require a secondary intracranial procedure. Patients with multisutural or syndromic craniosynostosis are at higher risk of needing repeat surgery due to insufficient outcome of skull shape or raised intracranial pressure. Specific surgical techniques such as biparietal outfracturing and endoscopic stripcraniectomy with helmet therapy have shown poorer outcomes for some types of craniosynostosis.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2021)
Article
Clinical Neurology
Turki Elarjani, Othman T. Almutairi, Modhi Alhussinan, Abdulelah Alturkistani, Fahad S. Alotaibi, Mohammed Bafaquh, Fahad E. Alotaibi
Summary: Craniosynostosis presents a therapeutic challenge due to its diversity, with bibliometric analysis revealing changes in research trends focusing on neurogenetics and surgical corrections. Highly-cited publications can aid physicians in understanding evidence-based approaches in craniosynostosis.
CHILDS NERVOUS SYSTEM
(2021)
Article
Clinical Neurology
Summer Xu, Nathan K. Leclair, Sophia Angelo, Mitch Paro, Petronella Stoltz, Megan Anderson, Jonathan E. Martin, David S. Hersh, Markus J. Bookland
Summary: The study aimed to quantify frontal deformities among patients with isolated metopic ridging, metopic craniosynostosis, and normocephalic head shapes, as well as document the natural history of frontal deformities in isolated metopic ridge patients in the first year of life. Results showed that isolated metopic ridge patients with frontal bone angulations > 2.2 radians exhibited mild frontal constriction that did not significantly worsen over the first year of life.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2023)
