Article
Cell Biology
Daniel Dautan, Adrienn Kovacs, Tsogbadrakh Bayasgalan, Miguel A. Diaz-Acevedo, Balazs Pal, Juan Mena-Segovia
Summary: CnF and PPN neurons in the MLR demonstrate distinct physiological properties and connectivity patterns, contributing to short-lasting muscle activation and long-lasting muscle tone increase in motor behavior, respectively.
Article
Neurosciences
Ya-Juan Zhao, Yang Liu, Jian Wang, Qiang Li, Zhou-Ming Zhang, Teng Tu, Rong Lei, Min Zhang, Yong-Jin Chen
Summary: Psychological stress is closely associated with temporomandibular disorder (TMD), specifically masticatory muscle disorder. This study investigated the central mechanism underlying masticatory muscle overactivity induced by chronic stress. The results showed that chronic restraint stress can activate Vme neurons, enhance glutamatergic excitatory projections from Vme to Vmo, and result in masseter muscle overactivity.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Neurosciences
Hiroki Toyoda, Jonghwa Won, Wheedong Kim, Hayun Kim, Oscar Davy, Mitsuru Saito, Doyun Kim, Takuma Tanaka, Youngnam Kang, Seog Bae Oh
Summary: Noradrenergic neurons in the locus coeruleus release noradrenaline via volume transmission to activate extrasynaptic G-protein coupled receptors in target cells, affecting the currents in MTN neurons. The different modes of LC activation lead to varying degrees of current inhibition in MTN neurons.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Manuel J. Ferreira-Pinto, Harsh Kanodia, Antonio Falasconi, Markus Sigrist, Maria S. Esposito, Silvia Arber
Summary: Research has shown the existence of functionally diverse neuronal populations in the mesencephalic locomotor region, with some controlling full-body behavior and others controlling forelimb behavior, stratified by projection target and exhibiting roles in action control beyond locomotion.
Article
Mathematics, Applied
Shijie Zhou, Wei Lin
Summary: The paper introduces an adaptive scheme with heterogeneous delay interactions to suppress synchronization in a large population of oscillators, highlighting the potential advantages of using an exponential distribution. The scheme successfully demonstrates synchronization elimination in realistic neuronal networks, providing insights for deepening the understanding and refining existing techniques of deep brain stimulation in treating synchronization-induced mental disorders.
Article
Neurosciences
Qasim A. El-Dwairi, Saleh M. Al-Hussain, Ayat S. Banihani, Ziad M. Bataineh, Laiche Djouhri, Ayman G. Mustafa, Sami Zaqout
Summary: The morphological study of neurons in the spinal trigeminal nucleus of camels using the Golgi impregnation method revealed at least 12 morphological types of neurons with various sizes, shapes, and appendages. These neurons exhibited unique adaptations, such as large dilatations especially at their dendritic branching points, suggesting evolutionary modifications in pain and temperature processing pathways. This study provides insights into the neural adaptations of camels living in harsh environments with frequent exposure to painful stimuli.
Article
Mathematics, Applied
XinYue Chen, Ran Chen, YiLin Sun, Shuai Liu
Summary: In this study, we examined the effect of coupling scheme asymmetry on oscillator dynamics in a star network. Through numerical and analytical approaches, we determined stability conditions for various collective behavior states, ranging from equilibrium point to complete synchronization and quenched hub incoherence to remote synchronization. The coupling asymmetry factor alpha was found to significantly influence and determine the stable parameter region of each state. The findings, supported by theoretical analysis and validated through numerical simulations, offer practical methods for controlling, restoring, or obstructing specific collective behavior.
Article
Medicine, Research & Experimental
Kohji Sato
Summary: The paper discusses the reasons for the presence of the mesencephalic nucleus of the trigeminal nerve (Me5) inside the brain and the characteristics of its neurons. The author hypothesizes that the emergence of jaws required a new sensory system, and the appearance of Me5 met this need.
MEDICAL HYPOTHESES
(2021)
Article
Medicine, Research & Experimental
Weihua Ding, Lukas Fischer, Qian Chen, Ziyi Li, Liuyue Yang, Zerong You, Kun Hu, Xinbo Wu, Xue Zhou, Wei Chao, Peter Hu, Tewodros Mulugeta Dagnew, Daniel M. Dubreuil, Shiyu Wang, Suyun Xia, Caroline Bao, Shengmei Zhu, Lucy Chen, Changning Wang, Brian Wainger, Peng Jin, Jianren Mao, Guoping Feng, Mark T. Harnett, Shiqian Shen
Summary: Cortical neural dynamics mediate information processing for the cerebral cortex, playing a crucial role in various biological processes and diseases. Spontaneous pain in neuropathic pain activates a specific area within the primary somatosensory cortex, resulting in synchronized neural dynamics. Manipulating the cortical network or applying clinically effective pain therapies can attenuate this synchronization and alleviate pain-like behavior.
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Mathematics, Applied
Karthikeyan Rajagopal, Shaobo He, Prakash Duraisamy, Anitha Karthikeyan
Summary: This study introduces a new discrete neuron model that can be easily implemented in digital circuits. By using time series plots, bifurcation plots, and frequency bifurcations, the dynamics of the model are investigated. Different network topologies are considered to analyze wave propagation phenomenon and spiral wave formation.
Article
Multidisciplinary Sciences
Katharina Ziegler, Ross Folkard, Antonio J. Gonzalez, Jan Burghardt, Sailaja Antharvedi-Goda, Jesus Martin-Cortecero, Emilio Isaias-Camacho, Sanjeev Kaushalya, Linette Liqi Tan, Thomas Kuner, Claudio Acuna, Rohini Kuner, Rebecca Audrey Mease, Alexander Groh
Summary: The authors demonstrate that layers 5 and 6 of the somatosensory cortex control nociception through specific cortical and corticothalamic interactions. Activation of L6 drives aversive hypersensitivity and spontaneous nocifensive behavior, while L5 activation reduces sensory sensitivity and reverses inflammatory allodynia.
NATURE COMMUNICATIONS
(2023)
Article
Neurosciences
Martin Carbo-Tano, Mathilde Lapoix, Xinyu Jia, Olivier Thouvenin, Marco Pascucci, Francois Auclair, Feng B. Quan, Shahad Albadri, Vernie Aguda, Younes Farouj, Elizabeth M. C. Hillman, Ruben Portugues, Filippo Del Bene, Tod R. Thiele, Rejean Dubuc, Claire Wyart
Summary: Researchers investigate the mesencephalic locomotor region in larval zebrafish and its role in triggering forward locomotion by activating specific sets of hindbrain V2a reticulospinal neurons.
NATURE NEUROSCIENCE
(2023)
Article
Neurosciences
Susumu Tanaka, Soju Seki, Yudai Ono, Akifumi Enomoto, Mikihiko Kogo
Summary: The study revealed that orexin-A (Ox-A) can affect the membrane properties of mesencephalic trigeminal (Mes V) neurons in several ways, such as shortening the after-hyperpolarization duration, increasing interspike frequency during repetitive discharge, enhancing resonance, and increasing sodium current density. These effects indicate that Ox-A may enhance Mes V neuronal excitability by modulating various membrane properties.
NEUROSCIENCE LETTERS
(2021)
Article
Engineering, Mechanical
Qian Zhou, Du Qu Wei
Summary: Electric and chemical synapses play a crucial role in signal exchange between neurons. This paper introduces the magnetic field and electric field into the traditional neuron model to study the collective dynamics of neuronal network, and finds that varying electrical synapse coupling can change the effects of magnetic coupling strength and cell size on synchronization. Additionally, for lower magnetic field coupling strength and cell size, electrical synapse coupling can induce synchronization more effectively. The results obtained provide new insights into signal coding and transition between neurons.
NONLINEAR DYNAMICS
(2021)
Article
Biology
Jun Takatoh, Jae Hong Park, Jinghao Lu, Shun Li, P. M. Thompson, Bao-Xia Han, Shengli Zhao, David Kleinfeld, Beth Friedman, Fan Wang
Summary: This study developed a new method to track premotor circuits in the adult mouse, revealing unique spatial organizations of different premotor circuits and identifying premotor neurons that simultaneously innervate multiple motor nuclei.
Article
Otorhinolaryngology
Brian W. Blakley, Carlos E. A. Garcia, Suzete R. Da Sliva, Victor M. B. Florencio, James I. Nagy
ACTA OTO-LARYNGOLOGICA
(2015)
Article
Neurosciences
J. E. Rash, N. Kamasawa, K. G. Vanderpool, T. Yasumura, J. O'Brien, S. Nannapaneni, A. E. Pereda, J. I. Nagy
Article
Neurosciences
M. E. Rubio, J. I. Nagy
Article
Neurosciences
John E. Rash, Kimberly G. Vanderpool, Thomas Yasumura, Jordan Hickman, Jonathan T. Beatty, James I. Nagy
JOURNAL OF NEUROPHYSIOLOGY
(2016)
Article
Neurosciences
J. I. Nagy, J. E. Rash
EUROPEAN JOURNAL OF NEUROSCIENCE
(2017)
Article
Neurosciences
D. D. Tsao, S. G. Wang, B. D. Lynn, J. I. Nagy
EUROPEAN JOURNAL OF NEUROSCIENCE
(2017)
Article
Neurosciences
S. G. Wang, D. D. Tsao, K. G. Vanderpool, T. Yasumura, J. E. Rash, J. I. Nagy
EUROPEAN JOURNAL OF NEUROSCIENCE
(2017)
Article
Endocrinology & Metabolism
Lingling Lu, Adam D. Hogan-Cann, Andrea K. Globa, Ping Lu, James Nagy, Shernaz X. Bamji, Christopher M. Anderson
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2019)
Review
Neurosciences
James I. Nagy, Alberto E. Pereda, John E. Rash
NEUROSCIENCE LETTERS
(2019)
Review
Biochemistry & Molecular Biology
James I. Nagy, Alberto E. Pereda, John E. Rash
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2018)
Article
Neurosciences
J. I. Nagy, B. D. Lynn, J. M. M. Senecal, K. Stecina
Article
Neurosciences
J. I. Nagy, B. D. Lynn
Article
Neurosciences
W. Bautista, J. I. Nagy
EUROPEAN JOURNAL OF NEUROSCIENCE
(2014)
Article
Neurosciences
W. Bautista, D. A. McCrea, J. I. Nagy
Article
Neurosciences
Bruce D. Lynn, Xinbo Li, Sheriar G. Hormuzdi, Emily K. Griffiths, C. Jane McGlade, James I. Nagy
EUROPEAN JOURNAL OF NEUROSCIENCE
(2018)