Article
Multidisciplinary Sciences
Brian G. Rash, Jon I. Arellano, Alvaro Duque, Pasko Rakic
Summary: The convolutions of the mammalian cerebral cortex allow for enlargement of its surface and the addition of new functional areas while minimizing expansion of the skull. Neurodevelopmental disorders in humans are often associated with impaired cortical folding. Research suggests that the primary forces driving cortical folding include neuronal growth, formation of neuropil, glial cell intercalation, and the growth of subcortical white matter.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Neurosciences
Sophie K. Scott, Kyle Jasmin
Summary: This paper discusses the processing of sound in primate brains, proposing a general auditory processing framework that is supported by recent research findings.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Daniel Franjic, Mario Skarica, Shaojie Ma, Jon Arellano, Andrew T. N. Tebbenkamp, Jinmyung Choi, Chuan Xu, Qian Li, Yury M. Morozov, David Andrijevic, Zvonimir Vrselja, Ana Spajic, Gabriel Santpere, Mingfeng Li, Shupei Zhang, Yang Liu, Joshua Spurrier, Le Zhang, Ivan Gudelj, Lucija Rapan, Hideyuki Takahashi, Anita Huttner, Rong Fan, Stephen M. Strittmatter, Andre M. M. Sousa, Pasko Rakic, Nenad Sestan
Summary: The hippocampal-entorhinal system supports cognitive functions and has neurogenic capabilities in many species. This study profiled the single-nucleus transcriptomes in different subregions of the hippocampal-entorhinal system in humans, macaques, and pigs. The findings revealed species differences in neurogenesis and cellular diversity, as well as the association between certain proteins and Alzheimer's disease.
Article
Neurosciences
Brian Mathias, Andrea Waibel, Gesa Hartwigsen, Leona Sureth, Manuela Macedonia, Katja M. Mayer, Katharina von Kriegstein
Summary: The study found that sensorimotor-enriched training can change the representations of L2 words in the motor cortex, thereby facilitating the translation of L2 words. Different training methods have different effects on the translation speed of L2 words.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neuroimaging
Nicoletta Manzo, Giorgio Leodori, Giulia Ruocco, Daniele Belvisi, Shabbir Hussain I. Merchant, Giovanni Fabbrini, Alfredo Berardelli, Antonella Conte
Summary: This study aimed to investigate the effects of sensory trick (ST) on cortical activity in patients with cervical dystonia (CD) and explore the contribution of motor and sensory components to ST mechanisms. The results showed that ST can improve the dystonic posture in CD patients, and both motor and sensory components contribute to the ST effect.
NEUROIMAGE-CLINICAL
(2023)
Article
Multidisciplinary Sciences
Karthikeyan Balasubramanian, Fritzie I. Arce-McShane, Brian M. Dekleva, Jennifer L. Collinger, Nicholas G. Hatsopoulos
Summary: A spatiotemporal pattern of excitability propagates across the primary motor cortex prior to voluntary movements in non-human primates, and this pattern was also observed in a human participant during a wrist extension task. The propagation directions were bimodally distributed across the cortical sheet with opposite orientations, while the propagation speed was unimodally distributed and similar across tasks and species. The results suggest that this propagating pattern is a generic movement initiation signal that is invariant to kinematic or kinetic details.
Review
Biochemistry & Molecular Biology
Il Bin Kim, Seon-Cheol Park
Summary: Depression is characterized by impairments in adult neurogenesis, particularly in the hippocampus. Disruption of hippocampal neurogenesis in depression may be a consequence of neural circuitry impairments, with the entorhinal cortex playing a regulatory role. However, the exact mechanisms by which disruption of neural circuitry leads to neurogenesis impairments in depression, specifically regarding the regulatory role of the entorhinal cortex, remain unclear.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell & Tissue Engineering
Nicolas Dray, Laure Mancini, Udi Binshtok, Felix Cheysson, Willy Supatto, Pierre Mahou, Sebastien Bedu, Sara Ortica, Emmanuel Than-Trong, Monika Krecsmarik, Sebastien Herbert, Jean-Baptiste Masson, Jean-Yves Tinevez, Gabriel Lang, Emmanuel Beaurepaire, David Sprinzak, Laure Bally-Cuif
Summary: The study shows that neural stem cells coordinate their decision to divide in the adult zebrafish brain using spatiotemporally resolved local feedback signals, including short-range inhibition from transient neural progenitors and a dispersion effect from the dividing NSCs themselves. These signals are linked by lineage progression and control the spatiotemporal distribution of output neurons, generating self-propagating dynamics that maintain NSC population homeostasis.
Article
Neurosciences
Alexandra Korzeczek, Annika Primassin, Alexander Wolff von Gudenberg, Peter Dechent, Walter Paulus, Martin Sommer, Nicole E. Neef
Summary: Improved fluency in persons who stutter after one-year fluency-shaping therapy is accompanied by increased connectivity within the sensorimotor integration network, with strengthened connections between the left inferior frontal gyrus and key brain regions involved in speech production. This therapy-associated neural remediation is based on enhancing the command-to-execution pathway and auditory-to-motor coupling.
Article
Neurosciences
Dong Sun, Leena Milibari, Jin-Xiu Pan, Xiao Ren, Ling-Ling Yao, Yang Zhao, Chen Shen, Wen-Bing Chen, Fu-Lei Tang, Daehoon Lee, Jun-Shi Zhang, Lin Mei, Wen-Cheng Xiong
Summary: The research identified the critical functions of Ocn-Cre(+) dDG neurons in suppressing anxiety-like behaviors and promoting adult DG neurogenesis, likely through the activation of BDNF.
BIOLOGICAL PSYCHIATRY
(2021)
Article
Clinical Neurology
Gustavo Balbinot, Boris Touvykine, Joyce Zaftis, Clarissa Pedrini Schuch, Matthew Strider Jeffers, Guillaume Elgbeili, Numa Dancause, Dale Corbett
Summary: This study investigated the mechanisms of poststroke recovery using behavioral and kinematic analyses. The results showed that enriched rehabilitation can improve motor function recovery by restoring the function of motor-related structures. This study is important for understanding the process of motor recovery and identifying targets for optimizing poststroke recovery.
Article
Engineering, Biomedical
Wei Li, Chong Li, Aixian Liu, Ping-Ju Lin, Linhong Mo, Hongliang Zhao, Quan Xu, Xiangzun Meng, Linhong Ji
Summary: Sensory stimulation can induce lesion-specific activation patterns of S1-M1, which suggests that focal vibration could be applied in a personalized manner based on the lesion-specific activation in stroke patients with different lesion profiles and types. This study contributes to a better understanding of the underlying mechanisms of cortical reorganization.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Neurosciences
Manon Bohic, Aman Upadhyay, Jaclyn T. Eisdorfer, Jessica Keating, Rhiana C. Simon, Brandy A. Briones, Chloe Azadegan, Hannah D. Nacht, Olisemeka Oputa, Alana M. Martinez, Bridget N. Bethell, Mark A. Gradwell, Peter Romanienko, Matt S. Ramer, Garret D. Stuber, Victoria E. Abraira
Summary: Improvements in expression profiling of neuronal tissues allow for the analysis of finer subgroups of neurons. This study establishes a new workflow for dissecting adult spinal function based on developmental lineages. A brain-sparing mouse line is generated to restrict gene manipulation to the spinal cord.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Dmitry Frank, Benjamin F. Gruenbaum, Israel Melamed, Julia Grinshpun, Yair Benjamin, Ievgeni Vzhetson, Nadia Kravchenko, Michael Dubilet, Matthew Boyko, Alexander Zlotnik
Summary: After traumatic brain injury (TBI), impairments to sensory, short-term, and long-term memory are common side effects. Animal models, particularly rodent models, provide suitable alternatives to test treatment methods and study the mechanisms and complications of TBI. Test protocols such as metric tasks offer a feasible way to evaluate impairment in spatial working memory (SWM) in adult rats after TBI.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2021)
Article
Pediatrics
Jawaria Shahid, Ayesha Kashif, Muhammad Kashif Shahid
Summary: Spasticity is common in children with bilateral spastic CP. SDR is a surgical procedure used to reduce lower limb rigidity, along with other treatment options such as intrathecal medication and DBS. The aim is to improve quality of life, and this article provides information for parents' counseling and treatment planning.
Article
Neurosciences
Karen M. Fisher, Alayna Lilak, Joseph Garner, Corinna Darian-Smith
JOURNAL OF COMPARATIVE NEUROLOGY
(2018)
Article
Neurosciences
Corinna Darian-Smith, Stephanie Hopkins, Henry J. Ralston
JOURNAL OF COMPARATIVE NEUROLOGY
(2010)
Article
Neurosciences
Corinna Darian-Smith, Alayna Lilak, Christina Alarcon
JOURNAL OF COMPARATIVE NEUROLOGY
(2013)
Article
Neurosciences
Corinna Darian-Smith, Alayna Lilak, Joseph Garner, Karen-Amanda Irvine
JOURNAL OF NEUROSCIENCE
(2014)
Review
Clinical Neurology
Corinna Darian-Smith
Article
Neurosciences
Matthew Crowley, Alayna Lilak, Jamie Ahloy-Dallaire, Corinna Darian-Smith
JOURNAL OF COMPARATIVE NEUROLOGY
(2019)
Article
Neurosciences
Margaret M. McCann, Karen M. Fisher, Jamie Ahloy-Dallaire, Corinna Darian-Smith
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Karen M. Fisher, Joseph P. Garner, Corinna Darian-Smith
JOURNAL OF NEUROSCIENCE
(2020)
Article
Behavioral Sciences
Matthew Crowley, Alayna Lilak, Joseph P. Garner, Corinna Darian-Smith
Summary: The study compared behavioral data from two established spinal injury models in monkeys and found that the extent of corticospinal terminal sprouting does not directly correlate with behavioral recovery.
BEHAVIOURAL BRAIN RESEARCH
(2022)
Article
Neurosciences
Karen M. Fisher, Joseph P. Garner, Corinna Darian-Smith
Summary: Small sensory spinal injuries can significantly impact sensory and motor spinal neurons, providing new insights into the recovery process.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Veterinary Sciences
Katherine L. Lucot, Syed A. Bukhari, Ebony D. Webber, T. Adam Bonham, Corinna Darian-Smith, Thomas J. Montine, Sherril L. Green
Summary: This study found that neurodegenerative changes similar to those in Alzheimer's disease were present in the brains of aged polar bears. The use of standardized assessment methods is important for studying aging in vulnerable wildlife species.
COMPARATIVE MEDICINE
(2022)
Article
Neurosciences
Mani Vessal, Ari Aycock, Margaret Tess Garton, Melanie Ciferri, Corinna Darian-Smith
EUROPEAN JOURNAL OF NEUROSCIENCE
(2007)
Article
Neurosciences
Christina G. von der Ohe, Craig C. Garner, Corinna Darian-Smith, H. Craig Heller
JOURNAL OF NEUROSCIENCE
(2007)
Review
Veterinary Sciences
Corinna Darian-Smith