Article
Clinical Neurology
S. Sharifi, F. Luft, S. Potgieter, T. Heida, W. Mugge, A. C. Schouten, L. J. Bour, A. F. van Rootselaar
Summary: The study aimed to clarify the role of the motor cortex in tremor generation in essential tremor (ET) and familial cortical myoclonic tremor with epilepsy (FCMTE). The results showed that the majority of ET patients lacked a linear cortical drive, with weaker ascending coupling in ET compared to healthy controls around 5-6 Hz.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Ya Sun, Lihui Huang, Qiaoling Hua, Qiang Liu
Summary: This study investigated the effects of transcranial alternating current stimulation (tACS) on verbal fluency and found that 10 Hz tACS significantly improved phonemic fluency. This result is important for understanding methods to enhance language expression ability.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Medicinal
Yoo-Hun Noh, Junkee Hong, Ji-Won Lee, Sung-Su Kim, Il-Jun Kang, Wan Kyunn Whang, Soon-Chul Myung, Myung-Hee Chung, Moo-Ho Won
Summary: The mixture of Clematis mandshurica Rupr. and Erigeron annuus Pers., YES-10, has anti-inflammatory properties and can improve mental health by reducing depression and anxiety.
JOURNAL OF MEDICINAL FOOD
(2022)
Article
Physiology
S. Walker, H. Piitulainen, T. Manlangit, J. Avela, S. N. Baker
EXPERIMENTAL PHYSIOLOGY
(2020)
Article
Neurosciences
Demetris S. Soteropoulos, Stuart N. Baker
JOURNAL OF NEUROSCIENCE
(2020)
Article
Neurosciences
K. M. Riashad Foysal, Stuart N. Baker
JOURNAL OF PHYSIOLOGY-LONDON
(2020)
Article
Neurosciences
Isabel S. Glover, Stuart N. Baker
JOURNAL OF NEUROSCIENCE
(2020)
Article
Neurosciences
Bonne Habekost, Maria Germann, Stuart N. Baker
Summary: Repeated paired stimulation of two peripheral nerves can produce lasting changes in motor cortical excitability, with asynchronous stimulation enhancing task performance and neural responses while synchronous stimulation impairs them. The changes in neural activity after paired stimulation can alter the efficiency of encoding stimulus type, indicating the potential of noninvasive stimuli to affect central motor circuits in human subjects.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Karen M. Fisher, Boubker Zaaimi, Steve A. Edgley, Stuart N. Baker
Summary: The study examined the corticoreticular connections in macaque monkeys and found a high degree of convergence. Reticulospinal neurons can integrate information from both sides of the motor cortex, adapting to bilateral motor context.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Maria Germann, Stuart N. Baker
Summary: Pairing clicks and muscle stimulation for long periods induces plasticity in subcortical systems such as the reticulospinal tract (RST). Changes were similar for either of the two paired stimulus rates tested, but absent after unpaired (control) stimulation.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Steve A. Edgley, Elizabeth R. Williams, Stuart N. Baker
Summary: Renshaw cells mediate recurrent inhibition between motoneurons in the spinal cord. The study found that recurrent inhibitory connections are strongest between motoneurons innervating shoulder muscles and elbow extensors, almost absent in intrinsic hand muscles. The connectivity often spans joints, reflecting the flexible usage of the primate upper limb.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Engineering, Biomedical
Thomas Guiho, Stuart N. Baker, Andrew Jackson
Summary: The study found that ventral epidural SCS elicits movements more easily than dorsal sites, which require higher current intensities and are attenuated throughout the training process. Dorsal epidural SCS and transcutaneous SCS were effective at facilitating supraspinal-evoked responses, especially at intermediate stimulation frequencies.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Veterinary Sciences
Henri Georges Michel Justin Bertrand, Joseph Adam Middleton, Stuart Nicolas Baker, Isabel Glover, Paul Andrew Flecknell
Summary: This study investigated the effect of alphaxalone on SEPs in a rhesus macaque, revealing that alphaxalone increased latency time and decreased amplitude of SEPs but maintained waveform structure. This suggests that alphaxalone could be a suitable general anaesthetic option in neuroscience research, veterinary, or human medicine.
LABORATORY ANIMALS
(2021)
Article
Geriatrics & Gerontology
Stuart Maitland, Stuart N. Baker
Summary: The study found that younger adults had a negative correlation between grip strength and connectivity of corticospinal and reticulospinal pathways, while older adults had a positive correlation. Older individuals who maintain or strengthen their reticulospinal tract are stronger than their peers.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Neurosciences
J. Ibanez, A. Del Vecchio, J. C. Rothwell, S. N. Baker, D. Farina
Summary: This study investigates the transmission speeds of cortical beta rhythms to arm and leg muscles during mild contractions in humans. Two improvements for estimating corticomuscular beta transmission delays are proposed, leading to the discovery that descending corticomuscular beta transmission is only slightly slower than expected from the fastest corticospinal pathways. Simulation results suggest two possible scenarios to explain fast corticomuscular transmission, with implications for our understanding of corticomuscular interactions.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Karen M. Fisher, Stuart N. Baker
Summary: Homonymous facilitation of the H reflex in the flexor carpi radialis can be produced by segmental spinal mechanisms and a supranormal period of nerve excitability, rather than propriospinal circuits specifically.
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2021)
Article
Clinical Neurology
Simin Rahman, Ummatul Siddique, Supriyo Choudhury, Nazrul Islam, Akash Roy, Purba Basu, Sidharth Shankar Anand, Mohammad Ariful Islam, Mohammad Selim Shahi, Abu Nayeem, Md Tauhidul Islam Chowdhury, Mohammad Shah Jahirul Hoque Chowdhury, John-Paul Taylor, Mark R. Baker, Stuart N. Baker, Hrishikesh Kumar
Summary: The study suggests that the subcortical networks encompassing dopaminergic pathways in the basal ganglia play a more important role than cortical networks in movement stopping. ocSSRT can be used to differentiate between AD and PD patients, and combining with other indices or biomarkers may increase early diagnostic accuracy.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2022)
Article
Neurosciences
Banashree Mondal, Supriyo Choudhury, Rebecca Banerjee, Akash Roy, Koustav Chatterjee, Purba Basu, Ravi Singh, Saptak Halder, Shantanu Shubham, Stuart N. Baker, Mark R. Baker, Hrishikesh Kumar
Summary: Non-invasive vagus nerve stimulation has shown significant efficacy in improving gait and motor function in patients with Parkinson's disease, with improvements in key gait parameters such as walking speed, stance time, and step length. Additionally, levels of inflammatory markers TNF-alpha and glutathione decreased, while BDNF levels increased significantly in serum after treatment with nVNS.
NPJ PARKINSONS DISEASE
(2021)