Article
Neurosciences
Kun Cheng, Qi Duan, Jianxing Hu, Chenxi Li, Xiaoxiao Ma, Xiangbing Bian, Caohui Duan, Yongqin Xiong, Jiaji Lin, Haoxuan Lu, Linlin Deng, Ze Li, Mengting Wei, Jinhao Lyu, Ling Chen, Xin Lou
Summary: This study aimed to evaluate the diagnostic value of ultrahigh-field MRI for brain tumors. The results showed that 7T MRI can provide better visualization of brain tumor details and increase tumor detail diagnostic confidence.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Review
Neurosciences
Mingguo Xie, Xiongfei Wang, Zejun Duan, Guoming Luan
Summary: Brain tumors involving cortical neurons can often lead to seizures, especially intractable focal seizures. Low-grade epilepsy-associated neuroepithelial tumors (LEATs), such as ganglioglioma (GG) and dysembryoplastic neuroepithelial tumor (DNET), have common clinicopathological features including seizure onsets at a young age, involvement of the temporal lobe, and a slow growth pattern. Surgical treatments with complete resection of tumors and epileptogenic zones offer the best chance for seizure control and recurrence-free survival in patients with LEATs. However, there is ongoing debate among experts regarding the classification and diagnosis of LEAT entities.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Joevin Sourdon, Tangi Roussel, Claire Costes, Patrick Viout, Maxime Guye, Jean-Philippe Ranjeva, Monique Bernard, Frank Kober, Stanislas Rapacchi
Summary: This study compared three single-voxel H-1-CMRS techniques for quantifying myocardial FA and Cr at 3 T. sLASER showed the lowest deviation and PRESS provided the highest SNR in FB scans. sLASER demonstrated better correlation with myocardial Cr content compared to PRESS, while FA measurements showed similar regression line slopes.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2021)
Review
Clinical Neurology
Eleonora Aronica, Emilio Ciusani, Antonietta Coppola, Cinzia Costa, Emilio Russo, Andrea Salmaggi, Fabio Perversi, Marta Maschio
Summary: Epilepsy is a common symptom in brain tumor patients. Understanding the shared mechanisms between tumors and epilepsy can help develop targeted therapies. Currently, anti-seizure medications show potential efficacy, but more high-quality clinical trials are needed to confirm their use in practice.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zi-Yang Fan, Yan-Wei Lin, Ruo-Yang Shi, Ling-Zhan Yu, Rui Wu, Qiu-Ying Yao, Luke D. Wesemann, Jiani Hu, Qi Liu, Yan Zhou, Sheng Chen, Lian-Ming Wu
Summary: Creatine distribution in myocardial segments of idiopathic inflammatory myopathy (IIM) patients was measured using cardiovascular magnetic resonance (CMR) chemical exchange saturation transfer (CEST) creatine mapping. CEST showed increased sensitivity in detecting subclinical myocardial changes compared to conventional CMR mapping sequences, making it a promising CMR sequence for screening subclinical myocardial damage.
EUROPEAN RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Jinyuan Zhou, Moritz Zaiss, Linda Knutsson, Phillip Zhe Sun, Sung Soo Ahn, Silvio Aime, Peter Bachert, Jaishri O. Blakeley, Kejia Cai, Michael A. Chappell, Min Chen, Daniel F. Gochberg, Steffen Goerke, Hye-Young Heo, Shanshan Jiang, Tao Jin, Seong-Gi Kim, John Laterra, Daniel Paech, Mark D. Pagel, Ji Eun Park, Ravinder Reddy, Akihiko Sakata, Sabine Sartoretti-Schefer, A. Dean Sherry, Seth A. Smith, Greg J. Stanisz, Pia C. Sundgren, Osamu Togao, Moriel Vandsburger, Zhibo Wen, Yin Wu, Yi Zhang, Wenzhen Zhu, Zhongliang Zu, Peter C. M. van Zijl
Summary: This paper reviews the current clinical APTw imaging approaches and provides recommendations for optimizing APTw brain tumor imaging. These recommendations will help achieve uniform clinical application and interpretation, and facilitate multi-center trials and routine clinical use.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Biophysics
Dinesh K. Deelchand, Adam Berrington, Ralph Noeske, James M. Joers, Arvin Arani, Joseph Gillen, Michael Schar, Jon-Fredrik Nielsen, Scott Peltier, Navid Seraji-Bozorgzad, Karl Landheer, Christoph Juchem, Brian J. Soher, Douglas C. Noll, Kejal Kantarci, Eva M. Ratai, Thomas H. Mareci, Peter B. Barker, Guelin Oz
Summary: The study developed a short-echo sLASER sequence that could be executed on different platforms within a B-1 limit of 15 μT, demonstrating good reproducibility across vendors.
NMR IN BIOMEDICINE
(2021)
Article
Clinical Neurology
Kenichiro Asano, Seiko Hasegawa, Masashi Matsuzaka, Hiroki Ohkuma
Summary: This study retrospectively analyzed the incidence of BTE in 601 patients with metastatic brain tumors, finding that significant risk factors for BTE included young age, male sex, breast cancer, tumors involving eloquent areas, brain edema, dissemination, and giant tumors.
JOURNAL OF NEUROSURGERY
(2022)
Review
Oncology
Nils Stenvagnes Hauff, Anette Storstein
Summary: This article provides an overview of the current knowledge in the management of tumor related epilepsy. Tumor molecular markers such as IDH1 mutation and MGMT methylation status may become future treatment targets. Prophylactic treatment is recommended for all brain tumor patients after the first seizure, and seizure control should be considered when evaluating tumor treatment efficacy. A multidisciplinary team is necessary for treating patients with brain tumors and epilepsy.
CURRENT ONCOLOGY REPORTS
(2023)
Article
Clinical Neurology
Gianfranco Natale, Federico Cucchiara, Guido Bocci
Summary: This review critically examines the historical link between seizures and endocranic neoplasms, from ancient folklore to modern studies, highlighting key milestones and developments in the research field.
Article
Neurosciences
Steve C. N. Hui, Mark Mikkelsen, Helge J. Zollner, Vishwadeep Ahluwalia, Sarael Alcauter, Laima Baltusis, Deborah A. Barany, Laura R. Barlow, Robert Becker, Jeffrey Berman, Adam Berrington, Pallab K. Bhattacharyya, Jakob Udby Blicher, Wolfgang Bogner, Mark S. Brown, Vince D. Calhoun, Ryan Castillo, Kim M. Cecil, Yeo Bi Choi, Winnie C. W. Chu, William T. Clarke, Alexander R. Craven, Koen Cuypers, Michael Dacko, Camilo de la Fuente-Sandoval, Patricia Desmond, Aleksandra Domagalik, Julien Dumont, Niall W. Duncan, Ulrike Dydak, Katherine Dyke, David A. Edmondson, Gabriele Ende, Lars Ersland, C. John Evans, Alan S. R. Fermin, Antonio Ferretti, Ariane Fillmer, Tao Gong, Ian Greenhouse, James T. Grist, Meng Gu, Ashley D. Harris, Katarzyna Hatz, Stefanie Heba, Eva Heckova, John P. Hegarty, Kirstin-Friederike Heise, Shiori Honda, Aaron Jacobson, Jacobus F. A. Jansen, Christopher W. Jenkins, Stephen J. Johnston, Christoph Juchem, Alayar Kangarlu, Adam B. Kerr, Karl Landheer, Thomas Lange, Phil Lee, Swati Rane Levendovszky, Catherine Limperopoulos, Feng Liu, William Lloyd, David J. Lythgoe, Maro G. Machizawa, Erin L. MacMillan, Richard J. Maddock, Andrei Manzhurtsev, Maria L. Martinez-Gudino, Jack J. Miller, Heline Mirzakhanian, Marta Moreno-Ortega, Paul G. Mullins, Shinichiro Nakajima, Jamie Near, Ralph Noeske, Wibeke Nordhoy, Georg Oeltzschner, Raul Osorio-Duran, Maria C. G. Otaduy, Erick H. Pasaye, Ronald Peeters, Scott J. Peltier, Ulrich Pilatus, Nenad Polomac, Eric C. Porges, Subechhya Pradhan, James Joseph Prisciandaro, Nicolaas A. Puts, Caroline D. Rae, Francisco Reyes-Madrigal, Timothy P. L. Roberts, Caroline E. Robertson, Jens T. Rosenberg, Diana-Georgiana Rotaru, Ruth L. O'Gorman Tuura, Muhammad G. Saleh, Kristian Sandberg, Ryan Sangill, Keith Schembri, Anouk Schrantee, Natalia A. Semenova, Debra Singel, Rouslan Sitnikov, Jolinda Smith, Yulu Song, Craig Stark, Diederick Stoffers, Stephan P. Swinnen, Rongwen Tain, Costin Tanase, Sofie Tapper, Martin Tegenthoff, Thomas Thiel, Marc Thioux, Peter Truong, Pim van Dijk, Nolan Vella, Rishma Vidyasagar, Andrej Vovk, Guangbin Wang, Lars T. Westlye, Timothy K. Wilbur, William R. Willoughby, Martin Wilson, Hans-Jorg Wittsack, Adam J. Woods, Yen-Chien Wu, Junqian Xu, Maria Yanez Lopez, David K. W. Yeung, Qun Zhao, Xiaopeng Zhou, Gasper Zupan, Richard A. E. Edden
Summary: The study aimed to assess the need for real-time field-frequency locking on MRI scanners by analyzing frequency drift data from 95 3T MRI scanners. The results showed relatively low levels of drift with differences across scanners, and both linear and nonlinear drifts were observed.
Article
Clinical Neurology
Marta Maschio, Andrea Maialetti, Diana Giannarelli, Tatiana Koudriavtseva, Edvina Galie, Alessandra Fabi
Summary: This retrospective observational study evaluated the efficacy, safety, and interactions with cancer treatment of different anti-seizure medications (ASMs) in patients with epilepsy-related brain metastases (BM). The study found a significant correlation between tumor site and the likelihood of seizures in this patient population. Additionally, over 50% of the patients responded well to monotherapy with new generation ASMs.
FRONTIERS IN NEUROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chongxue Bie, Peter C. M. van Zijl, Deng Mao, Nirbhay N. Yadav
Summary: This study presents a new approach to improve the application of ultrafast Z-spectroscopy (UFZ) in the human body, making it more stable and accurate. By applying saturation gradients and readout gradients in the slice direction and phase encoding in the in-plane directions, high-resolution Z-spectra can be obtained. The results show that this method allows for better quantification and mapping of saturation transfer effects, opening up new possibilities for brain imaging.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Editorial Material
Oncology
Kiarash Shamardani, Michelle Monje
Summary: In this study, Sanchez-Aguilera et al. utilized in vivo electrocorticography and machine learning to investigate the effects of brain metastases on neural circuit dynamics. They found that the electrophysiological profile could predict the presence and type of brain metastasis.
Article
Biochemistry & Molecular Biology
Maxim Azarkin, Martin Kirakosyan, Vladimir Ryabov
Summary: This paper presents an assessment of nuclear reaction yields in human tissue-equivalent material during proton therapy, using Geant 4 simulation. The study also examines the effect of radiosensitizer nanoparticles on the enhancement of nuclear reactions. The results show that proton beams induce noticeable nuclear reactions in the tissue, but the contribution of radiosensitizer nanoparticles is negligible.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)