Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

Phenotyping the Function of TRPV1-Expressing Sensory Neurons by Targeted Axonal Silencing

(2013) C. Brenneis et al.   JOURNAL OF NEUROSCIENCE

Rapid optical control of nociception with an ion-channel photoswitch

(2012) Alexandre Mourot et al.   NATURE METHODS

TRPA1 Mediates Mechanical Sensitization in Nociceptors during Inflammation

(2012) Richard C. Lennertz et al.   PLoS One

The Quaternary Lidocaine Derivative, QX-314, Exerts Biphasic Effects on Transient Receptor Potential Vanilloid Subtype 1 Channels In Vitro

(2011) Ricardo E. Rivera-Acevedo et al.   ANESTHESIOLOGY

Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review

(2011) DP Roberson et al.   BRITISH JOURNAL OF PHARMACOLOGY

Acid Solution Is a Suitable Medium for Introducing QX-314 into Nociceptors through TRPV1 Channels to Produce Sensory-Specific Analgesic Effects

(2011) He Liu et al.   PLoS One

Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation

(2010) T. G. Banke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Activation of CaMKII and ERK1/2 contributes to the time-dependent potentiation of Ca2+ response elicited by repeated application of capsaicin in rat DRG neurons

(2010) Xiulin Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Experimental Characterization and Mathematical Modeling of P2X7 Receptor Channel Gating

(2010) Z. Yan et al.   JOURNAL OF NEUROSCIENCE

Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells

(2010) R. X. Faria et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Selectively targeting pain in the trigeminal system

(2010) Hyun Yeong Kim et al.   PAIN

Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels

(2009) Jun Chen et al.   Molecular Pain

Defining features of the hair cell mechanoelectrical transducer channel

(2009) Robert Fettiplace   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Properties of the Inner Pore Region of TRPV1 Channels Revealed by Block with Quaternary Ammoniums

(2008) Andrés Jara-Oseguera et al.   JOURNAL OF GENERAL PHYSIOLOGY

TRPV1 shows dynamic ionic selectivity during agonist stimulation

(2008) Man-Kyo Chung et al.   NATURE NEUROSCIENCE