Article
Neurosciences
Jaakko O. Nieminen, Alexey S. Pospelov, Lari M. Koponen, Pauliina Yrjola, Anastasia Shulga, Stanislav Khirug, Claudio Rivera
Summary: This study developed an experimental set-up for transcranial magnetic stimulation on rodents, overcoming technical difficulties caused by their small head size. The upside-down placement allowed easy navigation of the stimulation, and consistent motor evoked potentials were obtained.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Physiology
Olivier Girard, Martin Buchheit, Stuart Goodall, Sebastien Racinais
Summary: Exercise capacity decreases with increasing severity of hypoxia during exhaustive intermittent cycling, but neuromuscular fatigue characteristics do not differ significantly at task failure, and cardiovascular solicitation approaches maximal values in all conditions.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Engineering, Biomedical
Gansheng Tan, Jixian Wang, Jinbiao Liu, Yixuan Sheng, Qing Xie, Honghai Liu
Summary: This study proposes a corticomuscular network (CMN) approach to relate the electrophysiology of motor recovery and transcranial magnetic stimulation (TMS). Results showed that corticomuscular coherence (CMC) correlated positively with the Fugl-Meyer Assessment (FMA) for upper extremity. Compared to healthy controls, CMN of patients tended to be a small-world network with higher connectivity and coherence. Moreover, the impact of TMS on CMN parameters related to motor recovery was limited.
JOURNAL OF NEURAL ENGINEERING
(2022)
Review
Medicine, General & Internal
Leandro Ryuchi Iuamoto, Fabio Luis Kenji Ito, Thales Augusto Tome, Wu Tu Hsing, Alberto Meyer, Marta Imamura, Linamara Rizzo Battistella
Summary: This study contributes to a better understanding of the neurophysiological changes associated with knee osteoarthritis by observing neuroplasticity. These findings may aid in the early diagnosis of knee OA in the future. However, further research is still needed.
Article
Neurosciences
Brice T. Cleland, Sangeetha Madhavan
Summary: Motor overflow is a common occurrence after stroke, especially in the non-paretic upper limb. Two potential cortical mechanisms for this phenomenon are the control of both limbs by the contralesional hemisphere and the diminished inhibition from the ipsilesional to the contralesional hemisphere. However, there is limited research on differentiating between these hypotheses or studying motor overflow in the lower limb after stroke.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Clinical Neurology
Santosh A. Helekar, Jason Thonhoff, Blessy S. John, Lisa Nguyen, David B. Rosenfield, Stanley H. Appel
Summary: This study used a newly developed wearable transcranial rotating permanent magnet stimulator to measure the modulation of spontaneous motor unit potentials in hand muscles of patients with amyotrophic lateral sclerosis. The results showed a correlation between the modulation and the severity of the disease.
JOURNAL OF NEUROLOGY
(2022)
Article
Neurosciences
Kiana M. Young, Justin L. Rush, Adam S. Lepley, Adam M. Girmann, Grant E. Norte
Summary: Recording transcranial magnetic stimulation-derived measures during a closed kinetic chain task can assess corticomotor function for physically active individuals. The study aimed to determine the intersession reliability of quadriceps corticospinal excitability during a single-leg squat. The findings showed moderate-to-good reliability in dominant limb AMTs, but poor-to-moderate reliability in non-dominant limb AMTs and both limb MEPs. Further standardization is needed before incorporating this technique into clinical outcomes research.
Article
Geriatrics & Gerontology
Giorgio Varesco, Eric Luneau, Leonard Feasson, Thomas Lapole, Vianney Rozand
Summary: The study aimed to investigate age-related differences in fatigability during an isometric quadriceps intermittent fatiguing test. Older adults performed more relative contractions but had lower absolute force compared to young adults, with similar alterations in contractile function with age. Fatigue resistance was not maintained in very old adults, likely due to impairments in contractile function for all age groups.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
Jose E. Tecuapetla-Trejo, Jessica Cantillo-Negrete, Paul Carrillo-Mora, Raquel Valdes-Cristerna, Emmanuel Ortega-Robles, Oscar Arias-Carrion, Ruben I. Carino-Escobar
Summary: This study introduces an automatic method based on time-frequency features for extracting MEP amplitude and latency in stroke patients, which has the potential to reduce processing time and improve calculation accuracy.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2021)
Article
Physiology
Panpan Lu, Nicholas J. Hanson, Lin Wen, Feng Guo, Xiaoyu Tian
Summary: This study demonstrated the significant impact of transcranial direct current stimulation on muscle strength and explosive force of the non-dominant knee joint, potentially due to increased recruitment of motor units.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Psychiatry
Parmis Fatih, M. Utku Kucuker, Jennifer L. Vande Voort, Deniz Doruk Camsari, Faranak Farzan, Paul E. Croarkin
Summary: Based on 113 articles, it is suggested that LICI may serve as a biomarker of GABA(B) functioning, but more rigorous research is required. The existing LICI literature shows methodological heterogeneity and inconsistencies in findings, which are also non-specific to diseases. Future studies should address these weaknesses and focus on high-quality test-retest reliability.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Seung Yeon Jeon, Jung Ho Choi, Sun Seong Kang, Yong-Hwi An, Hyun Joon Shim
Summary: Personalized neuromodulation, where treatment modalities are chosen based on the patient's responses in a pilot trial, is an advantageous strategy for treating tinnitus. The study found that the improvement in Tinnitus Handicap Inventory (THI) score after 10 sessions of each neuromodulation was significantly greater in the personalized group compared to the randomized group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Neurosciences
Tingting Zhang, Bingqi Guo, Zhentao Zuo, Xiaojing Long, Shimin Hu, Siran Li, Xin Su, Yuping Wang, Chunyan Liu
Summary: This study aimed to evaluate the modulatory effects of transcranial focus ultrasound stimulation (tFUS) on human motor cortex excitability and explore the mechanism of neurotransmitter-related intracortical circuitry and plasticity. The results showed that tFUS can significantly increase M1 excitability, decrease intracortical inhibition, and change the concentration of GABA and Glx in the brain. These findings provide new insights into how tFUS can modulate cortical excitability and plasticity.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Medicine, General & Internal
Seong Hoon Bae, Seo Jin Moon, Jeong Gum Lee, Yun Kyung Yim, Hee So Oh, Dong Hee Han, In Seok Moon
Summary: The study compared the effects of rTMS and tDCS treatments for chronic tinnitus, showing comparable results in reducing tinnitus symptoms, with tDCS possibly being more cost-effective.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Physiology
Kosuke Hirata, Mari Ito, Yuta Nomura, Tsukasa Yoshida, Yosuke Yamada, Ryota Akagi
Summary: Maintenance and improvement of neuromuscular functions is crucial for everyone. Bioelectrical impedance analysis (BIA) can assess body electrical properties, such as phase angle (PhA), which is regarded as a muscle quantity/quality index. This study found that both thigh and whole-body PhA were associated with maximal voluntary muscle strength of the knee extensors, and this association may be due to intrinsic contractile properties but not neural aspects.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Physiology
Brodie J. Hand, George M. Opie, Simranjit K. Sidhu, John G. Semmler
Summary: The study found that endurance-trained cyclists had longer movement times, increased M1 plasticity, but no effect on visuomotor skill acquisition in a sequential visuomotor task.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Physiology
Jeroen Aeles, M. Bellett, G. A. Lichtwark, A. G. Cresswell
Summary: When the rate of force development is increased, neural drive also increases. Our experimental study provides evidence that a small increase in rate of force development leads to increased muscle fascicle shortening velocity, reducing the muscle's force-generating capacity, and resulting in the recruitment of active motor units at lower forces and with increased discharge frequencies.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Physiology
Lavender A. Otieno, John G. Semmler, Ashleigh E. Smith, Simranjit K. Sidhu
Summary: Age-related changes in the neuromuscular system can result in differences in fatigability between young and older adults. However, this study found that there were no age-related differences in GABA(B)-mediated inhibition following single-joint isometric fatiguing exercise of the elbow flexors, suggesting that GABA(B) modulation with aging may be muscle group dependent. Furthermore, variations in SP duration and LICI modulation during and post fatigue in both age groups suggest that these measures are likely mediated by divergent mechanisms.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Neurosciences
Aaron N. McInnes, An T. Nguyen, Timothy J. Carroll, Ottmar V. Lipp, Welber Marinovic
Summary: Intense sound can influence motor responses during muscle contraction, with different effects observed during action preparation. This study explores the impact of sustaining a muscle contraction during preparation for a ballistic action on the facilitation of motor output by a loud acoustic stimulus (LAS), known as the StartReact effect. The findings suggest that maintaining a low-force contraction in the contralateral limb enhances the facilitation by the LAS, which may have implications for stroke rehabilitation.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Article
Neurosciences
Samuele Contemori, Gerald E. Loeb, Brian D. Corneil, Guy Wallis, Timothy J. Carroll
Summary: This study demonstrates that symbolic cues can modulate express arm muscle responses in humans, suggesting cortical modulation of subcortical sensorimotor transformation nodes in the tecto-reticulo-spinal pathway.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Article
Sport Sciences
Ben W. Hoffman, Brent J. Raiteri, Mark J. Connick, Emma M. Beckman, Angelo Macaro, Vincent G. Kelly, Lachlan P. James
Summary: Combined heavy- and light-load ballistic training can improve athletic performance and induce adaptations in muscle structure. Little is known about the effects of training on muscle-tendon unit (MTU) kinetics during the execution of sport-specific skills. This study aimed to investigate the kinematics of the vastus lateralis (VL) MTU during a countermovement jump (CMJ) following combined ballistic training.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2022)
Article
Physiology
Brodie J. Hand, George M. Opie, Simranjit K. Sidhu, John G. Semmler
Summary: Previous research has shown that regular exercise increases plasticity in primary motor cortex (M1) and a single session of aerobic exercise can also increase M1 plasticity in untrained individuals. This study found that the effect of acute exercise on M1 plasticity is greater in endurance-trained cyclists compared to untrained individuals. Exercise history is an important factor in exercise-induced cortical plasticity.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Review
Neurosciences
Markus Amann, Simranjit K. Sidhu, Chris J. McNeil, Simon C. Gandevia
Summary: This review summarizes the changes in the corticomotoneuronal pathway during different types of exercise and discusses their relevance to the development of central fatigue, as well as the potential of non-invasive brain stimulation to enhance exercise performance.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Multidisciplinary Sciences
Eric Yung-Sheng Su, Timothy J. Carroll, Dominic J. Farris, Glen A. Lichtwark
Summary: Through computer modeling and simulation, we explored the potential influence of accentuated eccentric loading (AEL) on enhanced power and energy storage during vertical jumping. However, our model did not show improved jump performance with AEL, and there was no additional tendon-loading effect compared to non-AEL condition.
Article
Physiology
Patricio A. Pincheira, Dean L. Mayfield, Aaron S. Fox, Nicholas A. T. Brown, Timothy J. Carroll, Andrew G. Cresswell, Glen A. Lichtwark
Summary: This study investigated the effect of muscle force during active stretch on exercise-induced muscle damage. The results showed that adding 30% body weight during eccentric contractions did have some impact on muscle damage, but did not increase torque loss or intensify muscle soreness.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Physiology
Muneeb Iqbal, Edward Bliss, Eliza Whiteside, Ben Hoffman, Dean E. Mills
Summary: Respiratory muscle damage following inspiratory pressure threshold loading (ITL) can be assessed using markers such as CKM and fast/slow sTnI. CKM and fast sTnI are indicative of immediate (1h) damage, while CKM and slow sTnI can assess damage at 24 and 48h after ITL.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Biology
Luke N. Jessup, Luke A. Kelly, Andrew G. Cresswell, Glen A. Lichtwark
Summary: Many models have been developed to predict metabolic energy expenditure based on biomechanical proxies of muscle function. However, these models have not been rigorously tested across various locomotion tasks and have not adequately characterized different forms of locomotion. In this study, frequency and height constraints were imposed on hopping, and the effects on metabolic power and muscle function were evaluated. The results showed that a decrease in hop frequency and an increase in hop height led to an increase in metabolic power, which could be explained by changes in muscle activation and work requirements.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2023)
Article
Biology
Cristian D. Riveros-Matthey, Timothy J. Carroll, Glen A. Lichtwark, Mark J. Connick
Summary: People tend to choose higher cadences than metabolic optimal during bicycling, which may allow for optimal muscle power. However, it is unclear whether this is consistent across different power outputs.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2023)
Letter
Sport Sciences
Ben Hoffman, Brent Raiteri
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Meeting Abstract
Sport Sciences
Dean E. Mills, Ben Hoffman, Michael A. Johnson, Graham R. Sharpe, Joshua Rands, Shoena E. Wotherspoon, Yaroslav Gevorkov, Tracy L. Kolbe-Alexander, William MacAskill
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)